CAS 554-01-8

5-Methylcytosine

Description:

5-Methylcytosine is a modified nucleobase derived from cytosine, characterized by the addition of a methyl group at the carbon 5 position of the pyrimidine ring. This modification plays a crucial role in the regulation of gene expression and is a key component of epigenetic mechanisms in various organisms, including plants and mammals. It is commonly found in DNA, where it contributes to the stability of the double helix and influences the binding of transcription factors. The presence of 5-methylcytosine can affect chromatin structure and gene accessibility, thereby impacting cellular processes such as differentiation and development. In terms of physical properties, 5-methylcytosine is a white to off-white crystalline solid that is soluble in water and polar organic solvents. Its chemical formula is C5H6N2O, and it has a molecular weight of approximately 126.11 g/mol. The compound is of significant interest in molecular biology and genetics, particularly in studies related to DNA methylation patterns and their implications in health and disease.

Formula: C₅H₇N₃O

InChI: InChI=1S/C5H7N3O/c1-3-2-7-5(9)8-4(3)6/h2H,1H3,(H3,6,7,8,9)

InChI key: InChIKey=LRSASMSXMSNRBT-UHFFFAOYSA-N

SMILES: NC1=C(C)C=NC(=O)N1

Synonyms:

• 2(1H)-Pyrimidinone, 4-amino-5-methyl-
• 2(1H)-Pyrimidinone, 6-amino-5-methyl-
• 4-Amino-2-hydroxy-5-methylpyrimidine
• 4-Amino-5-methyl-2(1H)-pyrimidinone
• 5-Methylcytosin
• 5-Metilcitosina
• 6-Amino-5-methyl-2(1H)-pyrimidinone
• 6-amino-5-methylpyrimidin-2(1H)-one
• 6-amino-5-methylpyrimidin-2(1H)-one hydrochloride (1:1)
• Cytosine, 5-methyl-
• Nsc 137776

5-Methylcytosine, 97%

CAS: 554-01-8

5-Methylcytosine is used as a marker to protect DNA from being cut by native methylation-sensitive restriction enzymes. It is also employed in the production of 4-amino-5-hydroxy-5-methyl-2-oxo-2,5-dihydro-imidazole-1-carbaldehyde. This Thermo Scientific Chemicals brand product was originally part o

Formula: C₅H₇N₃O

Purity: 97%

Color and Shape: White to cream, Powder

Molecular weight: 125.13

Ref: 02-043492

2(1H)-Pyrimidinone, 4-amino-5-methyl-

CAS: 554-01-8

Formula: C₅H₇N₃O

Purity: 97%

Color and Shape: Solid

Molecular weight: 125.1286

Ref: IN-DA00I9VR

5-Methylcytosine

CAS: 554-01-8

5-Methylcytosine

Purity: 98%

Molecular weight: 125.13g/mol

Ref: 54-OR1011913

5-Methylcytosine

CAS: 554-01-8

5-Methylcytosine

Purity: ≥98%

Molecular weight: 125.13g/mol

Ref: 54-BUP17754

5-Methylcytosine

CAS: 554-01-8

5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA.

Formula: C₅H₇N₃O

Purity: 99.17%

Color and Shape: Solid

Molecular weight: 125.13

Ref: TM-T5270

5-Methylcytosine (~90%)

Controlled Product

CAS: 554-01-8

Applications 5-Methylcytosine (cas# 554-01-8) is a useful research chemical.

Formula: C₅H₇N₃O

Purity: ~90%

Color and Shape: Neat

Molecular weight: 125.13

Ref: TR-M294873

5-Methylcytosine

CAS: 554-01-8

5-Methylcytosine is a nucleic acid that is found in the DNA and RNA of the cell. It is an important component of methylation, which is the process by which a methyl group is added to a molecule. This process can lead to cellular transformation, a process that can cause cancer. 5-Methylcytosine has also been shown as a molecular pathogenesis factor in infectious diseases such as HIV and herpes simplex virus type 1. The presence of 5-methylcytosine in nuclear DNA has been detected by analytical techniques such as gas chromatography/mass spectrometry (GC/MS). There are many analytical methods, including GC/MS, that can be used to detect 5-methylcytosine in cellular nuclei.

Formula: C₅H₇N₃O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 125.13 g/mol

Ref: 3D-FM63889

5-Methylcytosine

CAS: 554-01-8

Formula: C₅H₇N₃O

Purity: 95%

Color and Shape: Solid

Molecular weight: 125.131

Ref: 10-F222199