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CAS 554-92-7

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Trimethobenzamide hydrochloride

Description:
Trimethobenzamide hydrochloride is a chemical compound primarily used as an antiemetic, effective in preventing nausea and vomiting, particularly in patients undergoing surgery or chemotherapy. It is a white to off-white crystalline powder that is soluble in water and exhibits a moderate level of stability under standard conditions. The compound functions by blocking dopamine receptors in the central nervous system, thereby inhibiting the vomiting reflex. Its chemical structure includes a benzamide moiety, which contributes to its pharmacological properties. Trimethobenzamide hydrochloride is typically administered orally or via injection, and its dosage may vary based on the clinical context and patient response. Side effects can include drowsiness, dizziness, and gastrointestinal disturbances. As with any medication, it is essential to consider contraindications and potential interactions with other drugs. Overall, Trimethobenzamide hydrochloride is a valuable therapeutic agent in managing nausea and vomiting, with a well-established profile in clinical use.
Formula:C21H28N2O5·ClH
InChI:InChI=1S/C21H28N2O5.ClH/c1-23(2)10-11-28-17-8-6-15(7-9-17)14-22-21(24)16-12-18(25-3)20(27-5)19(13-16)26-4;/h6-9,12-13H,10-11,14H2,1-5H3,(H,22,24);1H
InChI key:InChIKey=WIIZEEPFHXAUND-UHFFFAOYSA-N
SMILES:C(NCC1=CC=C(OCCN(C)C)C=C1)(=O)C2=CC(OC)=C(OC)C(OC)=C2.Cl
Synonyms:
  • 4-(2-Dimethylaminoethoxy)-N-(3,4,5-trimethoxybenzoyl)benzylamine hydrochloride
  • Anaus
  • Benzamide, N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxy-, hydrochloride (1:1)
  • Benzamide, N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxy-, monohydrochloride
  • Benzamide, N-[p-[2-(dimethylamino)ethoxy]benzyl]-3,4,5-trimethoxy-, hydrochloride
  • Benzamide, N-[p-[2-(dimethylamino)ethoxy]benzyl]-3,4,5-trimethoxy-, monohydrochloride
  • N-(4-(2-dimethylaminoethoxy)benzyl)-3,4,5-trimethoxybenzamide hydrochloride
  • N-[p-[2-(Dimethylamino)ethoxy]benzyl]-3,4,5-trimethoxybenzamide hydrochloride
  • Ro 2-9578
  • Tigan
  • See more synonyms
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