CAS 5542-92-7

Cladribine EP Impurity D

CAS: 5542-92-7

Formula: C₁₀H₁₂ClN₅O₃

Color and Shape: White To Off-White Solid

Molecular weight: 285.69

Ref: 4Z-C-160007

1’-epi-Cladribine

CAS: 5542-92-7

Applications 1’-epi-Cladribine is an impurity of Cladribine (C557500), a substituted purine nucleoside with antileukemic activity.
References Seto, S., et al.: J. Clin. Invest., 75, 377 (1985), Piro, L.D., et al.: N. Engl. J. Med., 322, 1117 (1990),

Formula: C₁₀H₁₂ClN₅O₃

Color and Shape: Neat

Molecular weight: 285.69

Ref: TR-C557495

Cladribine Impurity D

CAS: 5542-92-7

Cladribine Impurity D is a polymerase chain reaction (PCR) diagnostic agent that is used to identify the presence of Cladribine in the blood. Cladribine Impurity D binds to an RNA polymerase enzyme, which prevents it from synthesizing DNA and RNA, resulting in a lack of cell proliferation. This drug has been shown to be effective in treating bowel disease and solid tumours. It also has a number of side effects including interactions with other medications, such as natural compounds and autoimmune diseases, as well as bronchiolitis obliterans and lymphoma. Cladribine Impurity D also interacts with the IL-2 receptor on cells, which may cause allergic reactions. The MDA-MB-231 breast cancer cells are resistant to this drug due to their expression of the protein MCL-1.

Formula: C₁₀H₁₂ClN₅O₃

Purity: Min. 95%

Molecular weight: 285.69 g/mol

Ref: 3D-IC179959

Cladribine EP Impurity D

CAS: 5542-92-7

Formula: C₁₀H₁₂ClN₅O₃

Molecular weight: 285.69

Ref: ST-EA-CP-C40004