CAS 55466-04-1

Jujuboside A

Description:

Jujuboside A is a natural compound primarily derived from the jujube fruit (Ziziphus jujuba), which is known for its traditional medicinal properties. It belongs to the class of saponins and is characterized by its glycosidic structure, which contributes to its bioactivity. Jujuboside A exhibits various pharmacological effects, including anxiolytic, sedative, and neuroprotective properties, making it of interest in herbal medicine and pharmacology. The compound has been studied for its potential to modulate neurotransmitter systems, particularly in relation to stress and anxiety relief. Additionally, it may possess antioxidant and anti-inflammatory effects, contributing to its therapeutic potential. Jujuboside A is typically found in the form of a white to off-white powder and is soluble in water and organic solvents, which facilitates its extraction and use in various formulations. Its safety profile and efficacy are subjects of ongoing research, particularly in the context of traditional herbal remedies and modern therapeutic applications.

Formula: C₅₈H₉₄O₂₆

InChI: InChI=1S/C58H94O26/c1-23(2)15-25-16-56(8,72)47-26-9-10-32-54(6)13-12-33(53(4,5)31(54)11-14-55(32,7)57(26)21-58(47,84-25)76-22-57)80-51-46(83-50-43(71)38(66)34(62)24(3)77-50)44(28(61)19-74-51)81-52-45(82-49-41(69)35(63)27(60)18-73-49)40(68)37(65)30(79-52)20-75-48-42(70)39(67)36(64)29(17-59)78-48/h15,24-52,59-72H,9-14,16-22H2,1-8H3/t24-,25-,26+,27+,28-,29+,30+,31-,32+,33-,34-,35-,36+,37+,38+,39-,40-,41+,42+,43+,44-,45+,46+,47-,48+,49-,50-,51-,52-,54-,55+,56-,57-,58-/m0/s1

InChI key: InChIKey=KVKRFLVYJLIZFD-OQVAHBRNSA-N

SMILES: C[C@]12[C@@]34[C@@]([C@@]5([C@@](C3)(OC4)O[C@@H](C=C(C)C)C[C@]5(C)O)[H])(CC[C@@]1([C@]6(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]7[C@H](O[C@H]8[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O8)[C@@H](O[C@H]9[C@H](O[C@H]%10[C@H](O)[C@@H](O)[C@H](O)CO%10)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]%11O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%11O)O9)[C@@H](O)CO7)CC6)[H])[H])[H]

Synonyms:

• (3beta,14xi,16beta,23R)-20-hydroxy-16,23:16,30-diepoxydammar-24-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->6)-[beta-D-xylopyranosyl-(1->2)]-beta-D-glucopyranosyl-(1->3)]-L-arabinopyranoside
• (3β,16β,23R)-16,23:16,30-Diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl-(1→2)-O-[O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[β-<smallcap>D</smallcap>-xylopyranosyl-(1→2)]-β-<smallcap>D</smallcap>-glucopyranosyl-(1→3)]-α-<smallcap>L</span>-arabinopyranoside
• α-<span class="text-smallcaps">L</smallcap>-Arabinopyranoside, (3β,16β,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→2)-O-[O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[β-<smallcap>D</smallcap>-xylopyranosyl-(1→2)]-β-<smallcap>D</span>-glucopyranosyl-(1→3)]-
• α-L-Arabinopyranoside, (3β,16β,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-β-D-glucopyranosyl-(1→6)-O-[β-D-xylopyranosyl-(1→2)]-β-D-glucopyranosyl-(1→3)]-
• Jujuboside A
• (3β,16β,23R)-16,23:16,30-Diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-β-D-glucopyranosyl-(1→6)-O-[β-D-xylopyranosyl-(1→2)]-β-D-glucopyranosyl-(1→3)]-α-L-arabinopyranoside

Jujuboside A

CAS: 55466-04-1

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Formula: C₅₈H₉₄O₂₆

Color and Shape: White Powder

Molecular weight: 1206.60333

Ref: 45-1354717

α-​L-​Arabinopyranoside, (3β,​16β,​23R)​-​16,​23:16,​30-​diepoxy-​20-​hydroxydammar-​24-​en-​3-​yl O-​6-​deoxy-​α-​L-​mannopyranosyl-​(1→2)​-​O-​[O-​β-​D-​glucopyranosyl-​(1→6)​-​O-​[β-​D-​xylopyranosyl-​(1→2)​]​-​β-​D-​glucopyranosyl-​(1→3)​]​-

CAS: 55466-04-1

Formula: C₅₈H₉₄O₂₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 1207.3514

Ref: IN-DA00I9WH

Jujuboside A

CAS: 55466-04-1

Formula: C₅₈H₉₄O₂₆

Molecular weight: 1207.36

Ref: 7W-GY1525

Jujuboside A

CAS: 55466-04-1

Jujuboside A

Purity: ≥98%

Molecular weight: 1207.35g/mol

Ref: 54-BUP11056

Jujuboside A

CAS: 55466-04-1

Jujuboside A, a neuroprotective agent, can ameliorates behavioral disorders of the dementia mouse model induced by Aβ1-42. It possesses sedative , anticonvulsant , antianxiety, anti-proliferation, antioxidant, and anti-inflammatory effects, it can notably reduce the damage cause by ISO via promoting the phosphorylation of PI3K, Akt, and mTOR and inhibiting LC3 conversion, which may be a potential choice for the treatment of heart diseases. Jujuboside A can inhibit gamma aminobutyric acid type A receptor, and the hyperactivity of hippocampal CAl area induced by penicillin sodium.

Formula: C₅₈H₉₄O₂₆

Purity: 95%~99%

Molecular weight: 1207.36

Ref: BP-BP0813

Jujuboside A

CAS: 55466-04-1

Jujuboside A: glycoside from Semen Ziziphi Spinosae, may treat Alzheimer's, has neuro-inhibitory effects.

Formula: C₅₈H₉₄O₂₆

Purity: 98% - >99.99%

Color and Shape: Solid

Molecular weight: 1207.35

Ref: TM-T3782

Jujuboside a

CAS: 55466-04-1

Natural glycoside

Formula: C₅₈H₉₄O₂₆

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 1207.37

Ref: 5G-89719

Jujuboside A

CAS: 55466-04-1

Jujuboside A is a saponin compound, which is derived from the seeds of Ziziphus jujuba, commonly known as the jujube or Chinese date. It exhibits a range of biological activities, primarily through its modulation of neurotransmitter systems in the brain. Jujuboside A has been shown to interact with the gamma-aminobutyric acid (GABA)ergic system, enhancing the inhibitory neurotransmission that may lead to its calming and anxiolytic effects.

Formula: C₅₈H₉₄O₂₆

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 1,207.37 g/mol

Ref: 3D-OJ09904