CAS 55481-88-4

Mollugin

Description:

Mollugin is a naturally occurring compound primarily derived from the plant species *Mollugo nudicaulis*, belonging to the family Molluginaceae. It is characterized by its complex chemical structure, which includes multiple functional groups that contribute to its biological activity. Mollugin has garnered interest in the field of medicinal chemistry due to its potential pharmacological properties, including anti-inflammatory, antioxidant, and anticancer activities. The compound exhibits a range of biological effects, which may be attributed to its ability to modulate various cellular pathways. Additionally, Mollugin's solubility and stability in different solvents can vary, influencing its bioavailability and efficacy in therapeutic applications. Research into Mollugin is ongoing, with studies focusing on its mechanisms of action, potential therapeutic uses, and the synthesis of analogs to enhance its properties. As with many natural products, the exploration of Mollugin's characteristics continues to reveal its significance in both traditional medicine and modern pharmacology.

Formula: C₁₇H₁₆O₄

InChI: InChI=1/C17H16O4/c1-17(2)9-8-12-13(16(19)20-3)14(18)10-6-4-5-7-11(10)15(12)21-17/h4-9,18H,1-3H3

InChI key: InChIKey=VLGATXOTCNBWIT-UHFFFAOYSA-N

SMILES: C(OC)(=O)C1=C2C(=C3C(=C1O)C=CC=C3)OC(C)(C)C=C2

Synonyms:

• 2H-naphtho[1,2-b]pyran-5-carboxylic acid, 6-hydroxy-2,2-dimethyl-, methyl ester
• Methyl 6-hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate
• Rubimaillin
• Smb 00431
• Mollugin
• 2H-Naphtho[1,2-b]pyran-5-carboxylic acid
• Mollugin/rubiMaillin
• 6-Hydroxy-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5-carboxylic acid methyl ester
• Mollugin, 98%, from Rubia cordifolia L.
• 6-hydroxy-2, 2-dimethyl-, methylester
• RUBIMAILLIN; MOLLUGIN
• 2-DiMethyl-6-hydroxy-2H-naphtho[1,2-b]pyran-5-carboxylic acid Methyl ester
• 6-Hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylic Acid Methyl Ester
• 2,2-Dimethyl-6-hydroxy-2H-naphtho[1,2-b]pyran-5-carboxylic acid methyl ester
• MOLLUGIN(SH)

Mollugin

CAS: 55481-88-4

Formula: C₁₇H₁₆O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 284.3065

Ref: IN-DA00DE0G

Mollugin

CAS: 55481-88-4

Mollugin

Purity: ≥95%

Molecular weight: 284.31g/mol

Ref: 54-BUP10672

Mollugin

CAS: 55481-88-4

Formula: C₁₇H₁₆O₄

Molecular weight: 284.31

Ref: 7W-GY1430

Methyl 6-Hydroxy-2,2-Dimethyl-2H-Benzo[H]Chromene-5-Carboxylate

CAS: 55481-88-4

Methyl 6-Hydroxy-2,2-Dimethyl-2H-Benzo[H]Chromene-5-Carboxylate

Purity: 99%

Molecular weight: 284.31g/mol

Ref: 54-OR1013849

Mollugin

CAS: 55481-88-4

Mollugin is a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Mollugin has anticancer efficacy, can modulate the HER2, HO-1, Nrf2 , and NF- κB pathways.

Formula: C₁₇H₁₆O₄

Purity: 95%~99%

Molecular weight: 284.311

Ref: BP-BP1228

Mollugin

CAS: 55481-88-4

Formula: C₁₇H₁₆O₄

Purity: >98.0%(HPLC)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 284.31

Ref: 3B-M3091

Mollugin

CAS: 55481-88-4

Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.

Formula: C₁₇H₁₆O₄

Purity: 99.87% - ≥95%

Color and Shape: Solid

Molecular weight: 284.31

Ref: TM-T3673

Mollugin

CAS: 55481-88-4

Oxygen-heterocyclic compound

Formula: C₁₇H₁₆O₄

Purity: ≥ 95.0 % (HPLC)

Molecular weight: 284.31

Ref: 5G-80499

Mollugin

Controlled Product

CAS: 55481-88-4

Applications Mollugin is an anti-tumor agent inducing apoptosis and autophagy in various cancer models.
References Zhang, L. et al.: Biochem. Biophys. Res. Comm., 450, 247 (2014); Idhayadhulla, A. et al.: Bioorg. Chem., 52, 77 (2014);

Formula: C₁₇H₁₆O₄

Color and Shape: Neat

Molecular weight: 284.31

Ref: TR-M487600

Mollugin

CAS: 55481-88-4

Mollugin is a bioactive compound, which is derived from the plant Rubia cordifolia. As a phytochemical, it is part of the anthraquinone family, isolated through extraction processes from the root of its source plant. Its mode of action involves modulating various biochemical pathways, notably exhibiting anti-inflammatory, anticancer, and antioxidant activities. These effects are primarily mediated through the inhibition of specific enzymes and signaling pathways, including the NF-κB and MAPK pathways, which are central to inflammatory and cancer processes.

Purity: Min. 95%

Ref: 3D-FM145252