CAS 55487-93-9

4-Methylumbelliferyl β-D-fucoside

Description:

4-Methylumbelliferyl β-D-fucoside is a synthetic glycoside commonly used as a substrate in biochemical assays, particularly for the detection of fucosidase enzymes. This compound features a 4-methylumbelliferone moiety, which is a fluorescent marker, linked to a fucose sugar through a glycosidic bond. Its fluorescence can be measured upon enzymatic hydrolysis, making it a valuable tool in enzyme activity studies. The substance is typically a white to off-white powder and is soluble in water and organic solvents, facilitating its use in various laboratory settings. It is important to handle this compound with care, as with any chemical, following appropriate safety protocols. The CAS number 55487-93-9 uniquely identifies this compound in chemical databases, aiding in its recognition and procurement for research purposes. Overall, 4-Methylumbelliferyl β-D-fucoside serves as an important reagent in glycosidase activity assays, contributing to our understanding of carbohydrate metabolism and enzyme kinetics.

Formula: C₁₆H₁₈O₇

InChI: InChI=1S/C16H18O7/c1-7-5-12(17)23-11-6-9(3-4-10(7)11)22-16-15(20)14(19)13(18)8(2)21-16/h3-6,8,13-16,18-20H,1-2H3/t8-,13+,14+,15-,16+/m1/s1

InChI key: InChIKey=CQKHENXHLAUMBH-OSLYUKSHSA-N

SMILES: CC=1C=2C(=CC(O[C@H]3[C@H](O)[C@@H](O)[C@@H](O)[C@@H](C)O3)=CC2)OC(=O)C1

Synonyms:

• 2H-1-Benzopyran-2-one, 7-[(6-deoxy-β-<span class="text-smallcaps">D</span>-galactopyranosyl)oxy]-4-methyl-
• 4-Methylumbelliferone β-<span class="text-smallcaps">D</span>-fucopyranoside
• 4-Methylumbelliferyl β-<span class="text-smallcaps">D</span>-fucopyranoside
• 4-Methylumbelliferyl β-<span class="text-smallcaps">D</span>-fucoside
• 4-methyl-2-oxo-2H-chromen-7-yl 6-deoxy-beta-D-galactopyranoside
• 7-((6-Deoxy-beta-D-galactopyranosyl)oxy)-4-methyl-2H-1-benzopyran-2-one
• 7-[(6-Deoxy-β-<span class="text-smallcaps">D</span>-galactopyranosyl)oxy]-4-methyl-2H-1-benzopyran-2-one
• 2H-1-Benzopyran-2-one, 7-[(6-deoxy-β-D-galactopyranosyl)oxy]-4-methyl-
• 7-[(6-Deoxy-β-D-galactopyranosyl)oxy]-4-methyl-2H-1-benzopyran-2-one
• 4-Methylumbelliferyl β-D-fucoside
• 4-Methylumbelliferyl β-D-fucopyranoside

4-Methylumbelliferyl b-D-fucopyranoside

CAS: 55487-93-9

Ref: 7W-GC8963

4-Methylumbelliferyl β-D-Fucoside

CAS: 55487-93-9

Stability Hygroscopic
Applications 4-Methylumbelliferyl β-D-Fucoside is a fluorogenic substrate for β-D-Fucosidase, producing a blue fluorescent solution upon cleavage.

Formula: C₁₆H₁₈O₇

Color and Shape: Neat

Molecular weight: 322.31

Ref: TR-M337640

4-Methylumbelliferyl-β-D-fucopyranoside

CAS: 55487-93-9

4-Methylumbelliferyl-beta-D-fucopyranoside is a fluorogenic substrate for beta-fucosidase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl-beta-D-fucopyranosideas a substrate for measuring the beta-fucosidase activity is used for the diagnosis of fucosidosis and the study of glycoprotein metabolism disorder.

Formula: C₁₆H₁₈O₇

Purity: Min. 99 Area-%

Molecular weight: 322.31 g/mol

Ref: 3D-M-5540