CAS 555-30-6: Methyldopa
Description:Methyldopa, with the CAS number 555-30-6, is an antihypertensive medication primarily used to treat high blood pressure, particularly in pregnant women. It is classified as a centrally acting alpha-2 adrenergic agonist, which means it works by stimulating alpha-2 receptors in the central nervous system, leading to a decrease in sympathetic outflow and a subsequent reduction in blood pressure. Methyldopa is a white to off-white crystalline powder that is soluble in water and has a molecular formula of C10H13N3O4S. Its mechanism of action involves conversion to alpha-methyl norepinephrine, which mimics the action of norepinephrine but with a more pronounced effect on blood pressure regulation. Common side effects may include sedation, dry mouth, and potential liver function alterations. Methyldopa is typically administered orally and is known for its safety profile during pregnancy, making it a preferred choice in managing hypertension in expectant mothers.
Formula:C10H13NO4
InChI:InChI=1S/C10H13NO4/c1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6/h2-4,12-13H,5,11H2,1H3,(H,14,15)/t10-/m0/s1
InChI key:InChIKey=CJCSPKMFHVPWAR-JTQLQIEISA-N
SMILES:O=C(O)C(N)(C)CC1=CC=C(O)C(O)=C1
- Synonyms:
- (-)-α-Methyl-3,4-dihydroxyphenylalanine
- (-)-α-Methyldopa
- (2S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid
- (S)-(-)-alpha-Methyldopa
- (S)-(-)-α-Methyldopa
- 2-Methyl-3-(3,4-dihydroxyphenyl)alanine
- 3-Hydroxy-alpha-methyl-L-tyrosine
- 3-Hydroxy-α-methyl-<span class="text-smallcaps">L</span>-tyrosine
- 3-Hydroxy-α-methyl-L-tyrosine
- 3-hydroxy-N-methyltyrosine
- See more synonyms
- <span class="text-smallcaps">L</span>-(-)-α-Methyl-β-(3,4-dihydroxyphenyl)alanine
- <span class="text-smallcaps">L</span>-(-)-β-(3,4-Dihydroxyphenyl)-α-methylalanine
- <span class="text-smallcaps">L</span>-2-Amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic acid
- <span class="text-smallcaps">L</span>-3,4-Dihydroxy-α-methylphenylalanine
- <span class="text-smallcaps">L</span>-3,4-Dihydroxyphenyl-2-methylalanine
- <span class="text-smallcaps">L</span>-Methyldopa
- <span class="text-smallcaps">L</span>-Tyrosine, 3-hydroxy-α-methyl-
- <span class="text-smallcaps">L</span>-α-Methyl-3,4-dihydroxyphenylalanine
- <span class="text-smallcaps">L</span>-α-Methyl-3-(3,4)-dihydroxyphenylalanine
- <span class="text-smallcaps">L</span>-α-Methyldopa
- AMD
- Alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-, <span class="text-smallcaps">L</span>-
- Alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-, L-
- Aldochlor
- Aldomet
- Aldometil
- Aldomin
- Aldomine
- Alpha medopa
- Alphamethyldopa
- Bayer 1440L
- Baypresol
- Dopamet
- Dopatec
- Dopegyt
- Elanpres
- Equibar
- L-(-)-α-Methyl-β-(3,4-dihydroxyphenyl)alanine
- L-(-)-β-(3,4-Dihydroxyphenyl)-α-methylalanine
- L-2-Amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic acid
- L-3,4-Dihydroxy-α-methylphenylalanine
- L-3,4-Dihydroxyphenyl-2-methylalanine
- L-3-(3,4-Dihydroxyphenyl)-2-methylalanine
- L-Methyldopa
- L-Tyrosine, 3-hydroxy-α-methyl-
- L-α-Methyl-3,4-dihydroxyphenylalanine
- L-α-Methyl-3-(3,4)-dihydroxyphenylalanine
- Lederdopa
- Levo-3-(3,4-Dihydroxyphenyl)-2-methylalanine
- Medomet
- Medopa
- Medopren
- Methoplain
- Methyl-<span class="text-smallcaps">L</span>-dopa
- Methyl-L-dopa
- Methyldopa
- Metildopa
- Mk 351
- Nr.C 2294
- Nsc 169916
- Presinol
- Presolisin
- Sembrina
- l-α-Methyldopa
- α-Methyl-<span class="text-smallcaps">L</span>-3,4-dihydroxyphenylalanine
- α-Methyl-<span class="text-smallcaps">L</span>-dopa
- α-Methyl-L-3,4-dihydroxyphenylalanine
- α-Methyl-L-dopa
