CAS 55524-56-6

motilin, Nle(13)-

Description:

Motilin, Nle(13)- is a synthetic derivative of the natural peptide motilin, which plays a crucial role in gastrointestinal motility. This substance is characterized by its ability to stimulate gastric and intestinal motility, making it significant in the study of digestive processes. The modification at position 13, where leucine is replaced by norleucine (Nle), enhances its biological activity and stability compared to the native form. Motilin and its analogs are primarily involved in regulating the migrating motor complex, which is essential for the proper functioning of the digestive system. The CAS number 55524-56-6 uniquely identifies this compound, facilitating its recognition in scientific literature and databases. In terms of structure, motilin, Nle(13)- consists of a sequence of amino acids that contribute to its function as a hormone. Its pharmacological properties are of interest in both basic research and potential therapeutic applications, particularly in conditions related to gastrointestinal motility disorders.

Formula: C₁₂₁H₁₉₀N₃₄O₃₅

Synonyms:

• motilin, Nle(13)-
• L-Glutamine, L-phenylalanyl-L-valyl-L-prolyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-tyrosylglycyl-L-α-glutamyl-L-leucyl-L-glutaminyl-L-arginyl-L-norleucyl-L-glutaminyl-L-α-glutamyl-L-lysyl-L-α-glutamyl-L-arginyl-L-asparaginyl-L-lysylglycyl-

[Nle13]-Motilin

CAS: 55524-56-6

[Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist [1] [2] .

Formula: C₁₂₁H₁₉₀N₃₄O₃₅

Color and Shape: Solid

Molecular weight: 2681.01

Ref: TM-T76359