CAS 55541-30-5

Dexamethasone dipropionate

Description:

Dexamethasone dipropionate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is a derivative of dexamethasone, characterized by the addition of two propionate ester groups, which enhance its lipophilicity and prolong its action. This compound is typically used in various medical applications, including the treatment of inflammatory conditions, allergies, and certain autoimmune disorders. Dexamethasone dipropionate exhibits high potency and effectiveness in reducing inflammation and modulating immune responses. It is often administered via topical formulations or injections, depending on the condition being treated. The substance is known for its relatively low systemic side effects compared to other corticosteroids, although potential adverse effects can still occur, particularly with prolonged use. Its chemical structure contributes to its pharmacokinetic properties, allowing for sustained release and action at the site of inflammation. As with all corticosteroids, careful consideration of dosage and duration of treatment is essential to minimize risks associated with long-term use.

Formula: C₂₈H₃₇FO₇

InChI: InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19+,20+,21+,25+,26+,27+,28+/m1/s1

InChI key: InChIKey=CIWBQSYVNNPZIQ-PKWREOPISA-N

SMILES: C(COC(CC)=O)(=O)[C@]1(OC(CC)=O)[C@]2(C)[C@@](C[C@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]

Synonyms:

• (11Beta,16Alpha)-9-Fluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Diene-17,21-Diyl Dipropanoate
• (11β,16α)-9-Fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione
• 9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate)
• 9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate
• Dexamethasone 17,21-dipropionate
• Dexamethasone dipropionate
• Dexamethasone dipropionate [USAN]
• Methaderm
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-alpha-methyl-, 17,21-dipropionate
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11beta,16alpha)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11β,16α)-
• St 12
• St12
• Ths-101

Dexamethasone-17,21-Dipropionate

CAS: 55541-30-5

Formula: C₂₈H₃₇FO₇

Color and Shape: White To Off-White Solid

Molecular weight: 504.60

Ref: 4Z-D-3650

Dexamethasone Dipropionate

CAS: 55541-30-5

Applications A corticosteroid used in dermatology as a topical vasoconstrictor.
References Ikeda S., et al.: J. Dermatol. Sci., 5, 205 (1993), Tanigawa, K., et al.: Int. Immunopharmacol., 2, 941 (2002), Chen, B., et al.: Steroids, 74, 30 (2009),

Formula: C₂₈H₃₇FO₇

Color and Shape: Neat

Molecular weight: 504.59

Ref: TR-D298815

Dexamethasone dipropionate

Controlled Product

CAS: 55541-30-5

Dexamethasone dipropionate is a synthetic glucocorticoid with anti-inflammatory, immunosuppressive and antiproliferative properties. It is used to treat a number of inflammatory diseases such as rheumatoid arthritis, psoriasis, or ulcerative colitis. Dexamethasone dipropionate has also been used in the treatment of various types of cancers such as lymphomas or ovarian cancer. It has been shown to be effective against a range of different cancers in animal models. Dexamethasone dipropionate binds to receptors on cells that are involved in the inflammatory response and acts by blocking the production of prostaglandins and leukotrienes. This drug is biocompatible with human tissues and can be used for diagnostic purposes.

Formula: C₂₈H₃₇FO₇

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 504.59 g/mol

Ref: 3D-FD21404

Dexamethasone-17,21-dipropionate

CAS: 55541-30-5

Formula: C₂₈H₃₇FO₇

Molecular weight: 504.6

Ref: ST-EA-CP-D17056