CAS 55560-96-8

Tixocortol pivalate

Description:

Tixocortol pivalate is a synthetic corticosteroid primarily used for its anti-inflammatory and immunosuppressive properties. It is characterized by its ability to modulate the immune response and reduce inflammation, making it effective in treating various dermatological conditions. The substance is a derivative of prednisolone and is often utilized in topical formulations due to its favorable pharmacokinetic profile, which allows for localized action with minimal systemic absorption. Tixocortol pivalate exhibits a relatively low potential for skin irritation and is considered to have a lower risk of side effects compared to other corticosteroids. Its chemical structure includes a pivalate ester, which enhances its stability and solubility. The compound is typically administered in the form of ointments or creams, and its efficacy is often evaluated through clinical studies focusing on conditions such as eczema, psoriasis, and dermatitis. As with all corticosteroids, it is important to use tixocortol pivalate under medical supervision to avoid potential adverse effects associated with prolonged use.

Formula: C₂₆H₃₈O₅S

InChI: InChI=1S/C26H38O5S/c1-23(2,3)22(30)32-14-20(29)26(31)11-9-18-17-7-6-15-12-16(27)8-10-24(15,4)21(17)19(28)13-25(18,26)5/h12,17-19,21,28,31H,6-11,13-14H2,1-5H3/t17-,18-,19-,21+,24-,25-,26-/m0/s1

InChI key: InChIKey=BISFDZNIUZIKJD-XDANTLIUSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@H]3O)[C@](C(CSC(C(C)(C)C)=O)=O)(O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]

Synonyms:

• (11β)-21-[(2,2-Dimethyl-1-oxopropyl)thio]-11,17-dihydroxypregn-4-ene-3,20-dione
• 11beta,17-Dihydroxy-21-mercaptopregn-4-ene-3,20-dione 21-pivalate
• Jo 1016
• Pivalone
• Pregn-4-ene-3,20-dione, 21-((2,2-dimethyl-1-oxopropyl)thio)-11,17-dihydroxy-, (11beta)-
• Pregn-4-ene-3,20-dione, 21-[(2,2-dimethyl-1-oxopropyl)thio]-11,17-dihydroxy-, (11β)-
• Rectovalone
• S-(11beta,17-Dihydroxypregn-4-ene-3,20-dione) 21-(thiopivalate)
• S-[(11beta,14xi)-11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl] 2,2-dimethylpropanethioate
• S-[(11β)-11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl] 2,2-dimethylpropanethioate
• Tiovalon
• Tixocortol pivalate
• Tixocortol pivalate [USAN]

Tixocortol 21-Pivalate

CAS: 55560-96-8

Formula: C₂₆H₃₈O₅S

Molecular weight: 462.65

Ref: 4Z-T-259002

Tixocortol pivalate

CAS: 55560-96-8

Formula: C₂₆H₃₈O₅S

Purity: ≥ 97%

Color and Shape: White, off-white or light-yellow powder

Molecular weight: 462.64

Ref: 7W-GX2940

Tixocortol 21-Pivalate

Controlled Product

CAS: 55560-96-8

Applications Tixocortol 21-Pivalate is an anti-inflammatory agent. Tixocortol 21-Pivalate is used in fluorescent chemoaffinity labeling.
References Torossian, D.R., et al.: Arzneim.-Forsch., 31, 453 (1981),

Formula: C₂₆H₃₈O₅S

Color and Shape: Neat

Molecular weight: 462.64

Ref: TR-T447500

Tixocortol 21-Pivalate-d9

Controlled Product

CAS: 55560-96-8

Tixocortol 21-pivalate-d9 is a corticosteroid that is chemically stable at room temperature. It has been shown to have anti-inflammatory effects in the treatment of inflammatory bowel disease. Tixocortol 21-pivalate-d9 binds to the glucocorticoid receptor, which regulates many aspects of the immune response and inflammation. It also has been used for alopecia areata, allergic symptoms, and bowel disease. Tixocortol 21-pivalate-d9 is a low potency corticosteroid that has clinical relevance in the treatment of skin cancer and benzalkonium chloride.

Formula: C₂₆H₂₉D₉O₅S

Purity: Min. 95%

Molecular weight: 471.7 g/mol

Ref: 3D-FCA56096