Neodigoxin is a cardiac glycoside, a class of compounds known for their ability to influence heart contractions. It is derived from the plant Digitalis lanata and is structurally related to digoxin, which is commonly used in the treatment of heart conditions such as atrial fibrillation and heart failure. Neodigoxin exhibits similar pharmacological properties, including positive inotropic effects, which enhance the force of heart muscle contractions, and negative chronotropic effects, which can slow down heart rate. Its mechanism of action primarily involves the inhibition of the sodium-potassium ATPase pump, leading to increased intracellular calcium levels in cardiac cells. This results in improved cardiac output. Neodigoxin is characterized by its relatively high bioavailability and a narrow therapeutic index, necessitating careful monitoring of blood levels to avoid toxicity. Additionally, it may interact with various medications and is contraindicated in certain conditions, making it essential for healthcare providers to evaluate patient-specific factors before prescribing. Overall, neodigoxin represents an important therapeutic option in cardiology, albeit with careful consideration of its pharmacokinetics and potential side effects.

Neodigoxin

55576-67-5: Neodigoxin is a cardiac glycoside, a class of compounds known for their ability to influence heart contractions. It is derived from the plant Digitalis lanata and is structurally related to digoxin, which is commonly used in the treatment of heart conditions such as atrial fibrillation and heart failure. Neodigoxin exhibits similar pharmacological properties, including positive inotropic effects, which enhance the force of heart muscle contractions, and negative chronotropic effects, which can slow down heart rate. Its mechanism of action primarily involves the inhibition of the sodium-potassium ATPase pump, leading to increased intracellular calcium levels in cardiac cells. This results in improved cardiac output. Neodigoxin is characterized by its relatively high bioavailability and a narrow therapeutic index, necessitating careful monitoring of blood levels to avoid toxicity. Additionally, it may interact with various medications and is contraindicated in certain conditions, making it essential for healthcare providers to evaluate patient-specific factors before prescribing. Overall, neodigoxin represents an important therapeutic option in cardiology, albeit with careful consideration of its pharmacokinetics and potential side effects.

CAS 55576-67-5

Neodigoxin

Digoxin EP Impurity G

Ref: ST-EA-CP-D1200006

Digoxin EP Impurity G (Neodigoxin)

Ref: 4Z-D-757