CAS 55612-18-5

5-bromo-2'-deoxy-2'-fluorouridine

Description:

5-Bromo-2'-deoxy-2'-fluorouridine is a nucleoside analog that incorporates both bromine and fluorine substituents into the uridine structure. This compound is characterized by its ability to mimic natural nucleosides, which makes it of interest in antiviral and anticancer research. The presence of the bromine atom at the 5-position and the fluorine atom at the 2'-position alters the nucleoside's properties, potentially affecting its incorporation into nucleic acids and its interaction with enzymes involved in nucleic acid metabolism. This modification can enhance the compound's stability and bioactivity compared to its natural counterparts. 5-Bromo-2'-deoxy-2'-fluorouridine is typically studied for its effects on viral replication and its potential therapeutic applications in treating viral infections or cancer. Its chemical structure allows it to participate in various biochemical pathways, making it a valuable tool in molecular biology and medicinal chemistry. As with many nucleoside analogs, its pharmacokinetics, toxicity, and efficacy are important areas of ongoing research.

Formula: C₉H₁₀BrFN₂O₅

InChI: InChI=1/C9H10BrFN2O5/c10-3-1-13(9(17)12-7(3)16)8-5(11)6(15)4(2-14)18-8/h1,4-6,8,14-15H,2H2,(H,12,16,17)/t4-,5-,6-,8?/m1/s1

SMILES: c1c(c(nc(=O)n1C1[C@@H]([C@@H]([C@@H](CO)O1)O)F)O)Br

Synonyms:

• Uridine, 5-Bromo-2'-Deoxy-2'-Fluoro-
• 5-Bromo-2'-deoxy-2'-fluorouridine

5-Bromo-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS: 55612-18-5

5-Bromo-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Purity: 99%

Molecular weight: 325.09g/mol

Ref: 54-PC1006220

5-Bromo-2'-fluoro-2'-deoxyuridine

CAS: 55612-18-5

5-Bromo-2'-fluoro-2'-deoxyuridine is a Nucleoside, fluoro-modified nucleoside, halo-nucleoside.

Formula: C₉H₁₀BrFN₂O₅

Color and Shape: Solid

Molecular weight: 325.09

Ref: TM-TNU0621

5-Bromo-2'-deoxy-2'-fluorouridine

CAS: 55612-18-5

5-Bromo-2'-deoxy-2'-fluorouridine is a phosphoramidite that can be used as an anticancer, antiviral, and antimalarial agent. It is modified form of nucleosides with a high purity and quality. It has been shown to have antiviral activity against HIV type 1 and influenza A virus in vitro. 5-Bromo-2'-deoxy-2'-fluorouridine is a novel synthetic nucleoside that binds to the ribonucleotide reductase enzyme and inhibits its activity, which prevents the production of RNA. This drug also has anticancer properties due to its ability to inhibit DNA synthesis by binding to DNA polymerase and blocking the incorporation of deoxythymidylate into DNA. It also has been shown to cause cancer cell death by inhibiting protein synthesis.

Purity: Min. 95%

Ref: 3D-NB15625

5-Bromo-2'-deoxy-2'-fluorouridine

Controlled Product

CAS: 55612-18-5

Formula: C₉H₁₀BrFN₂O₅

Color and Shape: Neat

Molecular weight: 325.09

Ref: TR-B683715