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CAS 55612-21-0

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2'-deoxy-2'-fluoro-5-iodouridine

Description:
2'-Deoxy-2'-fluoro-5-iodouridine is a nucleoside analog that features a fluorine atom at the 2' position and an iodine atom at the 5' position of the uridine structure. This compound is characterized by its ability to mimic natural nucleosides, which makes it of interest in medicinal chemistry, particularly in antiviral and anticancer research. The presence of the fluorine atom enhances its stability and bioavailability, while the iodine substitution can influence its interaction with nucleic acid targets. This compound is typically used in studies related to nucleic acid synthesis and can exhibit unique biological activities due to its structural modifications. Its chemical properties include solubility in polar solvents and potential reactivity under specific conditions, making it a valuable tool in biochemical assays and drug development. As a nucleoside analog, it may interfere with nucleic acid metabolism, providing insights into cellular processes and therapeutic applications.
Formula:C9H10FIN2O5
InChI:InChI=1/C9H10FIN2O5/c10-5-6(15)4(2-14)18-8(5)13-1-3(11)7(16)12-9(13)17/h1,4-6,8,14-15H,2H2,(H,12,16,17)/t4-,5-,6-,8?/m1/s1
SMILES:c1c(c(nc(=O)n1C1[C@@H]([C@@H]([C@@H](CO)O1)O)F)O)I
Synonyms:
  • Uridine, 2'-Deoxy-2'-Fluoro-5-Iodo-
  • 5-Iodo-1-(2-Fluoro-2-Deoxyribofuranosyl)Uracil
  • 2'-Deoxy-2'-fluoro-5-iodouridine
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