CAS 55648-20-9
:Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,13E,15S)-, compd. with α-cyclodextrin (1:1)
Description:
Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,13E,15S)-, complexed with α-cyclodextrin, is a chemical compound that exhibits characteristics typical of both prostaglandin derivatives and cyclodextrin complexes. This substance is likely to possess anti-inflammatory and analgesic properties due to its prostaglandin-like structure, which is known to play a role in various physiological processes, including the modulation of pain and inflammation. The presence of hydroxyl groups enhances its solubility and potential reactivity, while the cyclodextrin component aids in improving the stability and bioavailability of the active compound by forming a host-guest complex. Cyclodextrins are cyclic oligosaccharides that can encapsulate hydrophobic molecules, thus facilitating their transport in biological systems. The specific stereochemistry indicated by the (11α,13E,15S) notation suggests a defined spatial arrangement that may influence the compound's biological activity and interaction with receptors. Overall, this compound represents a unique combination of bioactive properties and enhanced delivery potential due to its formulation with α-cyclodextrin.
Formula:C56H94O35
InChI:InChI=1/C36H60O30.C20H34O5/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44;1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h7-54H,1-6H2;12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b;13-12+/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-;15-,16+,17+,19+/m10/s1
InChI key:InChIKey=LYRPNNXUPAXZGU-CCCDWOKUSA-N
SMILES:C(O)[C@@H]1[C@@]2([C@H](O)[C@@H](O)[C@](O1)(O[C@@]3([C@@H](CO)O[C@@]([C@H](O)[C@H]3O)(O[C@@]4([C@@H](CO)O[C@@]([C@H](O)C4O)(O[C@]5([C@H](O)[C@@H](O)[C@@](O[C@]6([C@H](O)[C@@H](O)[C@@](O[C@]7([C@H](O)[C@@H](O)[C@@](O2)(O[C@@H]7CO)[H])[H])(O[C@@H]6CO)[H])[H])(O[C@@H]5CO)[H])[H])[H])[H])[H])[H])[H])[H].C(CCCCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)CC1=O
Synonyms:- Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,13E,15S)-, compd. with α-cyclodextrin (1:1)
- α-Cyclodextrin, compd. with (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid (1:1)
- Prostaglandin E1-α-cyclodextrin compd.
- PGE1-α-cyclodextrin inclusion compd.
- 2,4,7,9,12,14,17,19,22,24,27,29-Dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane, α-cyclodextrin deriv.
- Prost-13-en-1-oic acid,11,15-dihydroxy-9-oxo-,(11R,13E,15S)- ,coMpd. with R-cyclodextrin
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Found 4 products.
Alprostadil Alfadex
CAS:Controlled Product<p>Applications Alprostadil Alfadex is found to have a protective effect on radiation-induced proliferative inhibition and apoptosis in keratinocytes and healing of radiation-induced skin injury.<br>References Takikawa, M., et al.: Radiat. Res. 53, 385 (2012)<br></p>Formula:C36H60O30·C20H34O5Color and Shape:NeatMolecular weight:972.84 + 354.48Alprostadil alfadex
CAS:Alprostadil alfadex is a medicinal drug that has been found to have anticancer properties. It works by inhibiting the growth of cancer cells and inducing apoptosis, or programmed cell death. This drug is an analog of a naturally occurring protein that acts as a tumor inhibitor in humans. Alprostadil alfadex has been shown to be effective against various types of cancer, including those found in the urinary tract and prostate. It works by blocking the action of certain enzymes and proteins involved in the cell cycle, thereby preventing cancer cells from dividing and multiplying. Chinese researchers have also found that this drug has a kinase-inhibiting effect, which may contribute to its anticancer activity.Formula:C36H60O30•C20H34O5Purity:Min. 95%Color and Shape:PowderMolecular weight:1,327.3 g/mol
