CAS 5570-77-4

4-Chloro-1-methylpiperidine

Description:

4-Chloro-1-methylpiperidine is a chemical compound characterized by its piperidine ring structure, which is a six-membered saturated nitrogen-containing heterocycle. The presence of a chlorine atom at the fourth position and a methyl group at the first position of the piperidine ring defines its unique properties. This compound is typically a colorless to pale yellow liquid with a distinctive amine-like odor. It is soluble in organic solvents and exhibits moderate polarity due to the nitrogen atom. 4-Chloro-1-methylpiperidine is primarily used in organic synthesis and as an intermediate in the production of pharmaceuticals and agrochemicals. Its reactivity is influenced by the electron-withdrawing nature of the chlorine atom, which can affect nucleophilic substitution reactions. Safety considerations include handling it with care, as it may be harmful if inhaled or absorbed through the skin. Proper storage in a cool, dry place away from incompatible substances is essential to maintain its stability and prevent degradation.

Formula: C₆H₁₂ClN

InChI: InChI=1/C5H11ClN2/c6-5-1-3-8(7)4-2-5/h5H,1-4,7H2

InChI key: InChIKey=MYGXGCCFTPKWIH-UHFFFAOYSA-N

SMILES: ClC1CCN(C)CC1

Synonyms:

• 1-Methyl-4-chloropiperidine
• 1-Methyl-4-piperidinyl chloride
• 1-Methyl-4-piperidyl chloride
• 4-Chloro-1-Methyl-Piperidin
• 4-Chloro-1-Methylpiperidine
• 4-Chloro-1-Methylpiperidinium
• 4-Chloro-N-methylpiperidine
• 4-Chloropiperidin-1-Amine
• 4-chloro-N-Methyl piperidine
• N-Methyl-4-Chloropiperdine
• N-Methyl-4-chloro
• N-Methyl-4-chloropiperidene
• N-Methyl-4-chloropiperidine
• Piperidine, 4-chloro-1-methyl-
• N-Methyl-4-chloro piperidine
• 1-METHYL-4-CHLORO-PIPERIDINE
• N-Methyl-4-Chloropiperdine/4-Chloro-1-Methylpiperidine
• 4-CHLORO-N-METHYLPIPERIDINE HYDROCHLORIDE 97%

4-Chloro-1-methylpiperidine

CAS: 5570-77-4

Formula: C₆H₁₂ClN

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Light yellow to Light orange clear liquid to slightly cloudy liquid

Molecular weight: 133.62

Ref: 3B-C2465

4-Chloro-N-Methylpiperidine

CAS: 5570-77-4

Formula: C₆H₁₂ClN

Purity: 97%

Color and Shape: Liquid

Molecular weight: 133.6192

Ref: IN-DA003407

4-Chloro-1-methylpiperidine

CAS: 5570-77-4

4-Chloro-1-methylpiperidine

Purity: 98%

Color and Shape: Liquid

Molecular weight: 133.62g/mol

Ref: 54-OR8801

Loratadine Impurity 36

CAS: 5570-77-4

Formula: C₆H₁₂ClN

Molecular weight: 133.62

Ref: 4Z-L-1097

Ketotifen Impurity 2

CAS: 5570-77-4

Formula: C₆H₁₂ClN

Molecular weight: 133.62

Ref: ST-EA-CP-K1009

4-Chloro-1-methylpiperidine

CAS: 5570-77-4

Formula: C₆H₁₂ClN

Purity: 97%

Color and Shape: Solid

Molecular weight: 133.62

Ref: 10-F043308

4-Chloro-1-methylpiperidine

Controlled Product

CAS: 5570-77-4

Applications 4-Chloro-1-methylpiperidine is a reactant in the synthesis of indole and benzimidazole piperazines as histamine H4 receptor antagonist.
References Terzioglu, N., et. al.: Bioorg. Med. Chem. Lett., 14, 5251 (2004)

Formula: C₆H₁₂ClN

Color and Shape: Neat

Molecular weight: 133.62

Ref: TR-C371070

4-Chloro-N-methylpiperidine

CAS: 5570-77-4

4-Chloro-N-methylpiperidine is an inorganic acid that can be used as a reagent for the synthesis of organic compounds. It is also an anticholinergic drug and a halogenating agent. 4-Chloro-N-methylpiperidine can be used to treat bronchial asthma, chronic obstructive pulmonary disease, and other respiratory disorders by inhibiting the production of histamine in the body. It also has antihistaminic effects that may be due to its ability to inhibit histamine release from mast cells or block H1 receptors. This drug also has antiallergic effects, which may be due to its ability to inhibit IgE synthesis or function. 4-Chloro-N-methylpiperidine is found in loratadine (Claritin), which is used for allergies, hives, and other allergic reactions.

Formula: C₆H₁₂ClN

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 133.62 g/mol

Ref: 3D-FC29367