CAS 55721-11-4

24R,25-Dihydroxyvitamin D3

Description:

24R,25-Dihydroxyvitamin D3, with the CAS number 55721-11-4, is a biologically active metabolite of vitamin D3 (cholecalciferol) that plays a crucial role in calcium and phosphate metabolism in the body. This compound is characterized by the presence of two hydroxyl groups at the 24 and 25 positions of the vitamin D3 molecule, which enhances its solubility and biological activity. It is primarily produced in the liver and kidneys and is involved in various physiological processes, including bone health and immune function. The compound exhibits a unique mechanism of action, influencing gene expression through the vitamin D receptor (VDR). Its synthesis is regulated by factors such as sunlight exposure and dietary intake of vitamin D. Additionally, 24R,25-Dihydroxyvitamin D3 has been studied for its potential therapeutic effects in conditions like osteoporosis and certain autoimmune diseases. Overall, this metabolite is essential for maintaining optimal health and plays a significant role in the endocrine system.

Formula: C₂₇H₄₄O₃

InChI: InChI=1S/C27H44O3/c1-18-8-12-22(28)17-21(18)11-10-20-7-6-16-27(5)23(13-14-24(20)27)19(2)9-15-25(29)26(3,4)30/h10-11,19,22-25,28-30H,1,6-9,12-17H2,2-5H3/b20-10+,21-11-/t19-,22+,23-,24+,25-,27-/m1/s1

InChI key: InChIKey=FCKJYANJHNLEEP-XRWYNYHCSA-N

SMILES: C[C@@]12[C@](\C(=C\C=C\3/C(=C)CC[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](CC[C@H](C(C)(C)O)O)C)[H])[H]

Synonyms:

• (24R)-24,25-Dihydroxyvitamin D₃
• (24R)-Hydroxycalcidiol
• (3-Beta,5Z,7E,24R)-9,10-Secocholesta-5,7,10(19)-Triene-3,24,25-Triol
• (3R,5Z,7E,14xi,17xi,20xi,24R)-9,10-secocholesta-5,7,10-triene-3,24,25-triol
• (3R,6R)-2-Methyl-6-[(1R,3aS,4E,7aR)-octahydro-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]-7a-methyl-1H-inden-1-yl]-2,3-heptanediol
• (3R,6R)-6-[(1R,3aR,4E,7aR)-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylidene-cyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2-methyl-heptane-2,3-diol
• (3S,5Z,7E,14xi,17xi,20xi,24R)-9,10-secocholesta-5,7,10-triene-3,24,25-triol
• 2,3-Heptanediol, 2-methyl-6-[(1R,3aS,4E,7aR)-octahydro-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylenecyclohexylidene]ethylidene]-7a-methyl-1H-inden-1-yl]-, (3R,6R)-
• 24(R),25-Dihydroxycholecalciferol
• 24,25-Dihydroxycholecalciferol
• 24R,25-Dihydroxyvitamin D₃
• 24R,25R-dihydroxycholecalciferol
• 7,10(19)-Triene-3,24,25-Triol,(3-Beta,5Z,7E,24R)-10-Secocholesta-5
• 9,10-Secocholesta-5,7,10(19)-triene-3,24,25-triol, (3β,5Z,7E,24R)-
• K-Dr
• Osteo D
• Osteod
• Pri 1201
• Ro 21-5816
• Ro21-5816
• K-DR (Heptanediol)

Secalciferol

CAS: 55721-11-4

Secalciferol is a Vitamin D metabolite,Secalciferol is a possibly anti-inflammatory steroid which is involved in bone ossification.

Formula: C₂₇H₄₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 416.64

Ref: TM-T12874

Secalciferol

CAS: 55721-11-4

Formula: C₂₇H₄₄O₃

Molecular weight: 416.65

Ref: 4Z-S-182001

(24R)-24,25-Dihydroxyvitamin D3

CAS: 55721-11-4

Formula: C₂₇H₄₄O₃

Purity: ≥ 94%

Color and Shape: White to off-white solid

Molecular weight: 416.64

Ref: 7W-GV6226

Secalciferol

Controlled Product

CAS: 55721-11-4

Stability Light Sensitive, Temperature Sensitive
Applications A metabolite of Vitamin D, a possibly anti-inflammatory steroid.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Boyan, B., et al.: Steroids, 66, 363 (2001), Holick, M., et al.: J. Cell Biochem., 88, 296 (2003), Vogeser, M., et al.: Clin. Chem., 50, 1415 (2004), Singh, R., et al.: J. Clin. Endocrinol. Metab., 91, 3055 (2006),

Formula: C₂₇H₄₄O₃

Color and Shape: Neat

Molecular weight: 416.64

Ref: TR-S211500

Secalciferol

CAS: 55721-11-4

Secalciferol is a synthetic Vitamin D analog, which is derived from the structural modification of naturally occurring vitamin D compounds. It acts by binding to the vitamin D receptor (VDR) in target tissues, modulating gene expression to influence calcium and phosphate homeostasis. This mechanism is crucial in the regulation of bone mineralization and resorption processes.

Formula: C₂₇H₄₄O₃

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 416.64 g/mol

Ref: 3D-FS158458

Secalciferol

CAS: 55721-11-4

Formula: C₂₇H₄₄O₃

Molecular weight: 416.65

Ref: ST-EA-CP-C167006