CAS 55721-31-8

Salinomycin sodium

Description:

Salinomycin sodium is a polyether ionophore antibiotic that is primarily used in veterinary medicine, particularly for the prevention and treatment of coccidiosis in poultry. It is derived from the fermentation of the bacterium *Streptomyces albus*. Salinomycin functions by disrupting ion transport across cell membranes, leading to the inhibition of coccidian parasites. The compound is characterized by its ability to form complexes with monovalent cations, such as sodium and potassium, which facilitates the transport of these ions across lipid membranes. This mechanism of action not only affects parasites but can also influence mammalian cells, which has led to research into its potential anticancer properties. Salinomycin sodium is typically administered as a feed additive and is known for its relatively low toxicity in target animals. However, its use is regulated, and care must be taken to avoid residues in food products. Overall, salinomycin sodium is a significant compound in veterinary pharmacology with implications for both animal health and potential therapeutic applications in humans.

Formula: C₄₂H₇₀O₁₁·Na

InChI: InChI=1S/C42H70O11.Na/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33;/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47);/t23-,24-,25+,26-,27-,28-,29+,30-,31+,32+,33+,34+,36+,37-,39-,40+,41-,42-;/m0./s1

InChI key: InChIKey=PNDPFHFAPNOECJ-UZHRAPRISA-N

SMILES: O[C@H]1[C@]2(O[C@@]3(O[C@]([C@H](C([C@H]([C@H]([C@H](C)[C@@]4(O[C@@]([C@H](C(O)=O)CC)(CC[C@@H]4C)[H])[H])O)C)=O)CC)([C@@H](C)C[C@H]3C)[H])C=C1)O[C@@](C)(CC2)[C@@]5(O[C@@H](C)[C@](CC)(O)CC5)[H].[Na]

Synonyms:

• 1,6,8-Trioxadispiro[4.1.5.3]pentadecane, salinomycin deriv.
• Kokcisan
• Kokcisan 120G
• Sacox
• Salinomycin sodium
• Salinomycin, monosodium salt
• Salinomycin, sodium salt (1:1)
• Salinopharm-premix
• Sodium salinomycin
• Synvertas plv. a.u.v.
• Salinomycin, Sodium Salt

Salinomycin (sodium salt)

CAS: 55721-31-8

Formula: C₄₂H₆₉NaO₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 772.9804

Ref: IN-DA019FSO

Salinomycin sodium salt

CAS: 55721-31-8

Salinomycin sodium salt (Sodium salinomycin), an antibiotic potassium ionophore, is an effective inhibitor of Wnt/β-catenin signaling.

Formula: C₄₂H₆₉NaO₁₁

Purity: 98.76% - 99.11%

Color and Shape: White Or Light Yellow Crystalline Powder With Special Smel

Molecular weight: 772.98

Ref: TM-TQ0215

Salinomycin Sodium Salt

CAS: 55721-31-8

Formula: C₄₂H₆₉O₁₁·Na

Color and Shape: White To Off-White Solid

Molecular weight: 750.00 22.99

Ref: 4Z-S-241

Salinomycin sodium salt

CAS: 55721-31-8

Salinomycin sodium salt

Purity: ≥98%

Molecular weight: 772.98g/mol

Ref: 54-BUP16413

Salinomycin sodium salt

CAS: 55721-31-8

Formula: C₄₂H₆₉NaO₁₁·xH₂O

Purity: ≥ 97.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 772.98 (anhydrous)

Ref: 7W-GA1100

Salinomycin sodium

Controlled Product

CAS: 55721-31-8

Formula: C₄₂H₆₉O₁₁·Na

Color and Shape: Neat

Molecular weight: 772.98

Ref: 04-C16904500

Salinomycin sodium 100 µg/mL in Acetonitrile

CAS: 55721-31-8

Formula: C₄₂H₆₉O₁₁·Na

Color and Shape: Single Solution

Molecular weight: 772.98

Ref: 04-A16904500AL-100

Salinomycin Sodium Salt (12% min.)

Controlled Product

CAS: 55721-31-8

Applications Salinomycin is an ionophore antibiotic used in farming for the prevention of coccidiodomycosis in poultry and to alter gut flora in order to improve nutrient absorption in ruminants. An anticoccidial agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Porter, C., et al.: Poult Sci., 34, 995 (1955), Hancock, R., et al.: Lancet, 349, 418 (1997), Ogita, A., et al.: Toxicology, 215, 205 (2005), Usuki, Y., et al.: Bioorg. Med. Chem. Lett., 16, 1553 (2006), Ogita, A., et al.: J. Antibiot., 60, 511 (2007),

Formula: C₄₂H₆₉O₁₁·Na

Color and Shape: Neat

Molecular weight: 772.98

Ref: TR-S088800

Salinomycin Sodium Salt

Controlled Product

CAS: 55721-31-8

Applications Salinomycin is an ionophore antibiotic used in farming for the prevention of coccidiodomycosis in poultry and to alter gut flora in order to improve nutrient absorption in ruminants. An anticoccidial agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Porter, C., et al.: Poult Sci., 34, 995 (1955), Hancock, R., et al.: Lancet, 349, 418 (1997), Ogita, A., et al.: Toxicology, 215, 205 (2005), Usuki, Y., et al.: Bioorg. Med. Chem. Lett., 16, 1553 (2006), Ogita, A., et al.: J. Antibiot., 60, 511 (2007),

Formula: C₄₂H₆₉O₁₁·Na

Color and Shape: Off-White

Molecular weight: 772.98

Ref: TR-S088805

Salinomycin sodium

CAS: 55721-31-8

Salinomycin sodium is a model system for the study of the toxicity of drugs and chemicals. Salinomycin sodium can be used to study the effects of sublethal doses of salinomycin on metabolic enzymes in vitro. Salinomycin sodium has been shown to inhibit complex enzymes by intramolecular hydrogen bonding. This inhibition may lead to cell death or cytotoxicity.
Salinomycin is a compound that inhibits bacterial protein synthesis, which may be due to its interference with ribosome function or the binding of tRNA molecules to the ribosome. It also inhibits DNA replication, leading to cell death by inhibiting RNA synthesis or preventing DNA from being replicated. Salinomycin can also disrupt membrane permeability and induce lipid peroxidation in cells, leading to cell death.

Formula: C₄₂H₆₉NaO₁₁

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 772.98 g/mol

Ref: 3D-FS65155

Salinomycin Sodium

CAS: 55721-31-8

Formula: C₄₂H₆₉O₁₁Na

Molecular weight: 750.0 : 23.0

Ref: ST-EA-CP-S69001