CAS 55726-47-1

Enocitabine

Description:

Enocitabine, also known by its chemical name 4-amino-1-(2-deoxy-β-D-ribofuranosyl) pyrimidin-2(1H)-one, is a nucleoside analog that exhibits antiviral and antitumor properties. It is structurally similar to cytidine, featuring a modified ribose sugar that enhances its stability and bioavailability. Enocitabine functions primarily as an inhibitor of viral replication and has been investigated for its potential use in treating various viral infections and certain types of cancer. The compound is characterized by its ability to interfere with nucleic acid synthesis, thereby disrupting the proliferation of rapidly dividing cells, including those of tumors. Its mechanism of action involves incorporation into viral RNA or DNA, leading to termination of the nucleic acid chain. Enocitabine has been studied in clinical settings, although its therapeutic applications are still under evaluation. As with many nucleoside analogs, it may exhibit side effects related to its impact on both healthy and malignant cells, necessitating careful consideration in treatment regimens.

Formula: C₃₁H₅₅N₃O₆

InChI: InChI=1S/C31H55N3O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-27(36)32-26-22-23-34(31(39)33-26)30-29(38)28(37)25(24-35)40-30/h22-23,25,28-30,35,37-38H,2-21,24H2,1H3,(H,32,33,36,39)/t25-,28-,29+,30-/m1/s1

InChI key: InChIKey=SAMRUMKYXPVKPA-VFKOLLTISA-N

SMILES: O[C@@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(NC(CCCCCCCCCCCCCCCCCCCCC)=O)C=C2

Synonyms:

• 1-(beta-D-arabinofuranosyl)-4-(docosanoylamino)pyrimidin-2(1H)-one
• 4-(docosanoylamino)-1-pentofuranosylpyrimidin-2(1H)-one
• Behenoylcytosine arabinoside
• Bh-Ac
• Docosanamide, N-(1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-
• N-(1-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)docosanamide
• N4-Behenoyl-Ara-C
• N⁴-Behenoyl-1-β-<span class="text-smallcaps">D</span>-arabinofuranosylcytosine
• N⁴-Behenoylcytosine arabinoside
• NSC 239336
• Sunrabin
• N-(1-β-D-Arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)docosanamide
• N4-Behenoylcytosine arabinoside
• Docosanamide, N-(1-β-D-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-

Docosanamide,N-(1-b-D-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-

CAS: 55726-47-1

Formula: C₃₁H₅₅N₃O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 565.7849

Ref: IN-DA00I9XV

Enocitabine

CAS: 55726-47-1

Enocitabine

Purity: ≥95%

Molecular weight: 565.78g/mol

Ref: 54-BUP01269

Enocitabine

CAS: 55726-47-1

Formula: C₃₁H₅₅N₃O₆

Molecular weight: 565.78

Ref: 7W-GP9628

Enocitabine

CAS: 55726-47-1

Inhibitor of DNA polymerase; anti-leukemic agent

Formula: C₃₁H₅₅N₃O₆

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 565.40909

Ref: 3D-NE05152

Enocitabine

Controlled Product

CAS: 55726-47-1

Applications An antineoplastic. A derivative of Cytarabine.
References Aoshima, M., et al.: Cancer Res., 36, 2726 (1976), Akiyama, M., et al.: Chem. Pharm. Bull., 26, 981 (1978),

Formula: C₃₁H₅₅N₃O₆

Color and Shape: Neat

Molecular weight: 565.78

Ref: TR-E557500

Enocitabine

CAS: 55726-47-1

Enocitabine is a nucleoside analog.

Formula: C₃₁H₅₅N₃O₆

Purity: 97.22%

Color and Shape: Solid

Molecular weight: 565.78

Ref: TM-T15235