CAS 55726-47-1: Enocitabine

Description: Enocitabine, also known by its chemical name 4-amino-1-(2-deoxy-β-D-ribofuranosyl) pyrimidin-2(1H)-one, is a nucleoside analog that exhibits antiviral and antitumor properties. It is structurally similar to cytidine, featuring a modified ribose sugar that enhances its stability and bioavailability. Enocitabine functions primarily as an inhibitor of viral replication and has been investigated for its potential use in treating various viral infections and certain types of cancer. The compound is characterized by its ability to interfere with nucleic acid synthesis, thereby disrupting the proliferation of rapidly dividing cells, including those of tumors. Its mechanism of action involves incorporation into viral RNA or DNA, leading to termination of the nucleic acid chain. Enocitabine has been studied in clinical settings, although its therapeutic applications are still under evaluation. As with many nucleoside analogs, it may exhibit side effects related to its impact on both healthy and malignant cells, necessitating careful consideration in treatment regimens.

Formula: C₃₁H₅₅N₃O₆

InChI: InChI=1S/C31H55N3O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-27(36)32-26-22-23-34(31(39)33-26)30-29(38)28(37)25(24-35)40-30/h22-23,25,28-30,35,37-38H,2-21,24H2,1H3,(H,32,33,36,39)/t25-,28-,29+,30-/m1/s1

InChI key: InChIKey=SAMRUMKYXPVKPA-VFKOLLTISA-N

SMILES: O=C1N=C(C=CN1C2OC(CO)C(O)C2O)NC(=O)CCCCCCCCCCCCCCCCCCCCC

Synonyms:

• 1-(beta-D-arabinofuranosyl)-4-(docosanoylamino)pyrimidin-2(1H)-one
• 4-(docosanoylamino)-1-pentofuranosylpyrimidin-2(1H)-one
• Behenoylcytosine arabinoside
• Bh-Ac
• Docosanamide, N-(1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-
• N-(1-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)docosanamide
• N4-Behenoyl-Ara-C
• N⁴-Behenoyl-1-β-<span class="text-smallcaps">D</span>-arabinofuranosylcytosine
• N⁴-Behenoylcytosine arabinoside
• NSC 239336
• Sunrabin
• N-(1-β-D-Arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)docosanamide
• N4-Behenoylcytosine arabinoside
• Docosanamide, N-(1-β-D-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-
• N4-Behenoyl-1-β-D-arabinofuranosylcytosine

Docosanamide,N-(1-b-D-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)-

CAS: 55726-47-1

• Formula: C₃₁H₅₅N₃O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 565.7849

Enocitabine

CAS: 55726-47-1

• Purity: 98.01%
• Molecular weight: 565.78g/mol

Enocitabine

CAS: 55726-47-1

• Formula: C₃₁H₅₅N₃O₆
• Molecular weight: 565.78

Enocitabine

CAS: 55726-47-1

Inhibitor of DNA polymerase; anti-leukemic agent

• Formula: C₃₁H₅₅N₃O₆
• Purity: Min. 95%
• Color and Shape: Off-White Powder
• Molecular weight: 565.40909

Enocitabine

CAS: 55726-47-1

Applications An antineoplastic. A derivative of Cytarabine. References Aoshima, M., et al.: Cancer Res., 36, …

• Formula: C₃₁H₅₅N₃O₆
• Color and Shape: Neat
• Molecular weight: 565.78

Enocitabine

CAS: 55726-47-1

Enocitabine is a nucleoside analog.

• Formula: C₃₁H₅₅N₃O₆
• Purity: 98.02%
• Color and Shape: Solid
• Molecular weight: 565.78