CAS 55750-62-4: Succinimidyl 3-maleimidopropionate

Description: Succinimidyl 3-maleimidopropionate (SMP) is a chemical compound commonly used in bioconjugation and protein labeling applications. It features a succinimidyl ester group, which is reactive towards amine groups, allowing for the formation of stable amide bonds with proteins or other biomolecules. The maleimide group in SMP is particularly significant as it can selectively react with thiol groups, facilitating the conjugation of proteins or peptides that contain cysteine residues. This dual reactivity makes SMP a versatile crosslinker in biochemical research and therapeutic development. SMP is typically a white to off-white solid and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), but less soluble in water. It is important to handle SMP with care, as it can be sensitive to moisture and should be stored in a cool, dry place. Overall, SMP is a valuable tool in the field of biochemistry for creating stable conjugates for various applications, including drug delivery and diagnostic assays.

Formula: C₁₁H₁₀N₂O₆

InChI: InChI=1S/C11H10N2O6/c14-7-1-2-8(15)12(7)6-5-11(18)19-13-9(16)3-4-10(13)17/h1-2H,3-6H2

InChI key: InChIKey=JKHVDAUOODACDU-UHFFFAOYSA-N

SMILES: O=C1C=CC(=O)N1CCC(=O)ON2C(=O)CCC2=O

Synonyms:

• (2,5-Dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)propanoate
• 1-{3-[(2,5-dioxopyrrolidin-1-yl)oxy]-3-oxopropyl}-1H-pyrrole-2,5-dione
• 1H-Pyrrole-1-propanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
• 1H-Pyrrole-2,5-dione, 1-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]-
• 2,5-Dioxopyrrolidin-1-yl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate
• 2,5-Dioxopyrrolidin-1-yl 3-(2,5-dioxo-2,5-dihydro-lH-pyrrol-1-yl)propanoate
• 3-(2,5-Dioxo-2,5-dihydropyrrol-1-yl)propionic acid 2,5-dioxopyrrolidiny-1-yl ester
• 3-Maleimidopropionic acid N-hydroxysuccinimide ester
• 3-Maleimidopropionic acid N-succinimidyl ester
• 3-Maleimidopropionic acid hydroxysuccinimide ester
• BMPS (crosslinking agent)
• N-Succinimidyl 3-(N-maleimido)propionate
• Succinimidyl 3-maleimidopropanoate
• Succinimidyl 3-maleimidopropionate
• β-Maleimidopropionic acid N-hydroxysuccinimide ester
• N-Succinimidyl 3-maleimidopropionate

N-Succinimidyl 3-Maleimidopropionate [Cross-linking Reagent]

CAS: 55750-62-4

• Formula: C₁₁H₁₀N₂O₆
• Purity: >98.0%(HPLC)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 266.21

3-Maleimidopropionic acid N-hydroxysuccinimide ester, 99%

CAS: 55750-62-4

3-Maleimidopropionic acid N-hydroxysuccinimide ester is a reagent that is widely used for generating stable maleimide-activated …

• Formula: C₁₁H₁₀N₂O₆
• Purity: 99%
• Color and Shape: White to cream or pale yellow, Powder
• Molecular weight: 266.21

3-Maleimidopropionic acid N-hydroxysuccinimide ester

CAS: 55750-62-4

• Formula: C₁₁H₁₀N₂O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 266.2069

Maleimidopropionic acid N-hydroxysuccinimide ester

CAS: 55750-62-4

• Formula: C₁₁H₁₀N₂O₆
• Purity: 99% (hplc) (Typical Value in Batch COA)
• Color and Shape: white to off-white powder
• Molecular weight: 266.21g/mol

BMPS

CAS: 55750-62-4

BMPS, a non-cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).

• Formula: C₁₁H₁₀N₂O₆
• Color and Shape: Solid
• Molecular weight: 266.21

3-Maleimidopropionic acid N-hydroxysuccinimide ester, 99%

CAS: 55750-62-4

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₁H₁₀N₂O₆
• Purity: 99%
• Color and Shape: White to light yellow, Powder
• Molecular weight: 266.21

3-(Maleimido)propionic acid N-hydroxysuccinimide ester

CAS: 55750-62-4

• Purity: 97.0%
• Color and Shape: Solid, Crystalline Powder
• Molecular weight: 266.2090148925781

3-Maleimidopropionic Acid N-Succinimidyl Ester

CAS: 55750-62-4

Applications A short, sulfhydryl and amino reactive heterobifunctional crosslinking reagent. Also used in immunodiagnostics.Spacer Arm: …

• Formula: C₁₁H₁₀N₂O₆
• Color and Shape: Neat
• Molecular weight: 266.21

3-Maleimidopropionic acid N-succinimidyl ester

CAS: 55750-62-4

Please enquire for more information about 3-Maleimidopropionic acid N-succinimidyl ester including the price, delivery time …

• Formula: C₁₁H₁₀N₂O₆
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 266.21 g/mol

NHS-S-S-dPEG®4-Biotin (Cleavable)

CAS: 55750-62-4

NHS-S-S-dPEG®4-Biotin (Cleavable) is a biotinylated dextran sulfate that has been shown to have transfection activity …

• Formula: C₁₁H₁₀N₂O₆
• Purity: Min. 95%
• Molecular weight: 266.21 g/mol