CAS 5578-73-4

Sanguinarine hydrochloride

Description:

Sanguinarine hydrochloride is a quaternary ammonium salt derived from the plant Sanguinaria canadensis, commonly known as bloodroot. It is characterized by its yellow-orange crystalline appearance and is soluble in water, which enhances its bioavailability. This compound exhibits a range of biological activities, including antimicrobial, anti-inflammatory, and potential anticancer properties, making it of interest in both pharmacological and therapeutic research. Sanguinarine acts primarily by inhibiting various cellular processes, including those involved in cell proliferation and inflammation. Its mechanism of action often involves the modulation of signaling pathways and the induction of apoptosis in certain cancer cell lines. However, it is important to note that while sanguinarine has potential therapeutic benefits, it can also exhibit cytotoxic effects at higher concentrations. As with many bioactive compounds, further studies are necessary to fully understand its safety profile and efficacy in clinical applications. Proper handling and dosage are essential due to its potent biological effects.

Formula: C₂₀H₁₄NO₄·Cl

InChI: InChI=1S/C20H14NO4.ClH/c1-21-8-15-12(4-5-16-20(15)25-10-22-16)13-3-2-11-6-17-18(24-9-23-17)7-14(11)19(13)21;/h2-8H,9-10H2,1H3;1H/q+1;/p-1

InChI key: InChIKey=GIZKAXHWLRYMLE-UHFFFAOYSA-M

SMILES: C[N+]=1C2=C(C=3C(C1)=C4C(=CC3)OCO4)C=CC=5C2=CC6=C(C5)OCO6.[Cl-]

Synonyms:

• 13-Methyl[1,3]Benzodioxolo[5,6-C][1,3]Dioxolo[4,5-I]Phenanthridin-13-Ium Chloride
• 13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium chloride
• Sanguinarine hydrochloride
• Sanguinarium Chloride
• [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium, 13-methyl-, chloride
• [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium, 13-methyl-, chloride (1:1)
• Sanguinarine, chloride

Sanguinarine chloride

CAS: 5578-73-4

Sanguinarine chloride analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₂₀H₁₄NO₄Cl

Purity: (HPLC) ≥90%

Color and Shape: Powder

Molecular weight: 367.79

Ref: 11-1845

Sanguinarine chloride

CAS: 5578-73-4

Sanguinarine chloride (Pseudochelerythrine chloride), a benzophenanthridine alkaloid, stimulates apoptosis by activating the production of reactive oxygen

Formula: C₂₀H₁₄ClNO₄

Purity: 98% - 99.41%

Color and Shape: Solid

Molecular weight: 367.78

Ref: TM-T0129

[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium,13-methyl-, chloride (1:1)

CAS: 5578-73-4

Formula: C₂₀H₁₄ClNO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 367.7825

Ref: IN-DA0038NA

13-Methyl-[1,3]Dioxolo[4',5':4,5]Benzo[1,2-C][1,3]Dioxolo[4,5-I]Phenanthridin-13-Ium Chloride

CAS: 5578-73-4

13-Methyl-[1,3]Dioxolo[4',5':4,5]Benzo[1,2-C][1,3]Dioxolo[4,5-I]Phenanthridin-13-Ium Chloride

Purity: 99+%

Molecular weight: 367.78g/mol

Ref: 54-OR1025452

Sanguinarine chloride

CAS: 5578-73-4

Sanguinarine chloride

Purity: ≥98%

Molecular weight: 367.78g/mol

Ref: 54-BUP00054

Sanguinarine Chloride

CAS: 5578-73-4

Formula: C₂₀H₁₄NO₄·Cl

Molecular weight: 332.33 35.45

Ref: 4Z-S-190002

Sanguinarine chloride hydrate

CAS: 5578-73-4

Formula: C₂₀H₁₄ClNO₄·xH₂O

Purity: ≥ 98.0%

Color and Shape: Red to orange crystalline powder

Molecular weight: 367.78 (anhydrous)

Ref: 7W-GL9271

Sanguinarium chloride

CAS: 5578-73-4

Formula: C₂₀H₁₄NO₄Cl

Purity: 95%~99%

Molecular weight: 367.79

Ref: BP-BP1254

Sanguinarine Chloride Hydrate

CAS: 1099738-80-3, 2447-54-3, 5578-73-4

Formula: C₂₀H₁₄ClNO₄·xH₂O

Purity: >98.0%(HPLC)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 367.79 (as Anhydrous)

Ref: 3B-A3229

Sanguinarine chloride

CAS: 5578-73-4

Natural alkaloid

Formula: C₂₀H₁₄NO₄Cl

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 367.79

Ref: 5G-89327

Sanguinarium-13CD3 Chloride

Controlled Product

CAS: 5578-73-4

Formula: C₁₉CH₁₁D₃ClNO₄

Color and Shape: Neat

Molecular weight: 371.8

Ref: TR-S112502

Sanguinarium Chloride

CAS: 5578-73-4

Stability Hygroscopic
Applications Sanguinarium Chloride is a natural product with antimicrobial, anti-inflammatory, and anti-oxidant properties. Sanguinarium Chloride has antiproliferative, pro-apoptosis effects in some cancer cell lines.
References Ahmad, N., et al.: Clin. Cancer Res., 6, 1524 (2000), Adhami, V., et al.: Mol. Cancer Ther., 3, 933 (2004),

Formula: C₂₀H₁₄NO₄·Cl

Color and Shape: Neat

Molecular weight: 367.78

Ref: TR-S112500

Sanguinarium chloride

CAS: 5578-73-4

Sanguinarium chloride is a bioactive compound, which is an alkaloid derived from plants of the Papaveraceae family, particularly the bloodroot (Sanguinaria canadensis). This compound exhibits its mode of action primarily through its ability to disrupt cellular processes by binding to DNA and interfering with the transcriptional machinery of microbes and existing as an antimicrobial agent. Furthermore, Sanguinarium chloride has shown inhibitory effects on bacterial proliferation, making it of interest in the development of antimicrobial and antiplaque products.

Formula: C₂₀H₁₄ClNO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 367.78 g/mol

Ref: 3D-FS27791