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CAS 5578-73-4

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Sanguinarine hydrochloride

Description:
Sanguinarine hydrochloride is a quaternary ammonium salt derived from the plant Sanguinaria canadensis, commonly known as bloodroot. It is characterized by its yellow-orange crystalline appearance and is soluble in water, which enhances its bioavailability. This compound exhibits a range of biological activities, including antimicrobial, anti-inflammatory, and potential anticancer properties, making it of interest in both pharmacological and therapeutic research. Sanguinarine acts primarily by inhibiting various cellular processes, including those involved in cell proliferation and inflammation. Its mechanism of action often involves the modulation of signaling pathways and the induction of apoptosis in certain cancer cell lines. However, it is important to note that while sanguinarine has potential therapeutic benefits, it can also exhibit cytotoxic effects at higher concentrations. As with many bioactive compounds, further studies are necessary to fully understand its safety profile and efficacy in clinical applications. Proper handling and dosage are essential due to its potent biological effects.
Formula:C20H14NO4·Cl
InChI:InChI=1S/C20H14NO4.ClH/c1-21-8-15-12(4-5-16-20(15)25-10-22-16)13-3-2-11-6-17-18(24-9-23-17)7-14(11)19(13)21;/h2-8H,9-10H2,1H3;1H/q+1;/p-1
InChI key:InChIKey=GIZKAXHWLRYMLE-UHFFFAOYSA-M
SMILES:C[N+]=1C2=C(C=3C(C1)=C4C(=CC3)OCO4)C=CC=5C2=CC6=C(C5)OCO6.[Cl-]
Synonyms:
  • 13-Methyl[1,3]Benzodioxolo[5,6-C][1,3]Dioxolo[4,5-I]Phenanthridin-13-Ium Chloride
  • 13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium chloride
  • Sanguinarine hydrochloride
  • Sanguinarium Chloride
  • [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium, 13-methyl-, chloride
  • [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium, 13-methyl-, chloride (1:1)
  • Sanguinarine, chloride
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Found 13 products.
  • Sanguinarine chloride

    CAS:
    Sanguinarine chloride analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.
    Formula:C20H14NO4Cl
    Purity:(HPLC) ≥90%
    Color and Shape:Powder
    Molecular weight:367.79

    Ref: 11-1845

    10mg
    109.00€
  • Sanguinarine chloride

    CAS:
    <p>Sanguinarine chloride (Pseudochelerythrine chloride), a benzophenanthridine alkaloid, stimulates apoptosis by activating the production of reactive oxygen</p>
    Formula:C20H14ClNO4
    Purity:98% - 99.41%
    Color and Shape:Solid
    Molecular weight:367.78
  • [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium,13-methyl-, chloride (1:1)

    CAS:
    Formula:C20H14ClNO4
    Purity:95%
    Color and Shape:Solid
    Molecular weight:367.7825

    Ref: IN-DA0038NA

    1g
    271.00€
    50mg
    80.00€
    100mg
    115.00€
    250mg
    190.00€
  • 13-Methyl-[1,3]Dioxolo[4',5':4,5]Benzo[1,2-C][1,3]Dioxolo[4,5-I]Phenanthridin-13-Ium Chloride

    CAS:
    13-Methyl-[1,3]Dioxolo[4',5':4,5]Benzo[1,2-C][1,3]Dioxolo[4,5-I]Phenanthridin-13-Ium Chloride
    Purity:99+%
    Molecular weight:367.78g/mol

    Ref: 54-OR1025452

    1g
    323.00€
    100mg
    97.00€
    250mg
    162.00€
  • Sanguinarine chloride

    CAS:
    Sanguinarine chloride
    Purity:≥98%
    Molecular weight:367.78g/mol

    Ref: 54-BUP00054

    1g
    446.00€
    2g
    652.00€
    20mg
    80.00€
  • Sanguinarine Chloride

    CAS:
    Formula:C20H14NO4·Cl
    Molecular weight:332.33 35.45

    Ref: 4Z-S-190002

    5mg
    To inquire
    10mg
    444.00€
    25mg
    635.00€
    50mg
    825.00€
    100mg
    To inquire
  • Sanguinarine chloride hydrate

    CAS:
    Formula:C20H14ClNO4·xH2O
    Purity:≥ 98.0%
    Color and Shape:Red to orange crystalline powder
    Molecular weight:367.78 (anhydrous)

    Ref: 7W-GL9271

    25mg
    185.00€
  • Sanguinarium chloride

    CAS:
    Formula:C20H14NO4Cl
    Purity:95%~99%
    Molecular weight:367.79

    Ref: BP-BP1254

    20mg
    56.00€
    100mg
    103.00€
  • Sanguinarine Chloride Hydrate

    CAS:
    Formula:C20H14ClNO4·xH2O
    Purity:>98.0%(HPLC)
    Color and Shape:Light yellow to Brown powder to crystal
    Molecular weight:367.79 (as Anhydrous)

    Ref: 3B-A3229

    10mg
    182.00€
    50mg
    568.00€
  • Sanguinarine chloride

    CAS:
    Natural alkaloid
    Formula:C20H14NO4Cl
    Purity:≥ 95.0 % (HPLC)
    Color and Shape:Powder
    Molecular weight:367.79

    Ref: 5G-89327

    10mg
    183.00€
    50mg
    637.00€
    250mg
    2,908.00€
    500mg
    5,473.00€
    1000mg
    10,262.00€
  • Sanguinarium-13CD3 Chloride

    Controlled Product
    CAS:
    Formula:C19CH11D3ClNO4
    Color and Shape:Neat
    Molecular weight:371.8

    Ref: TR-S112502

    250µg
    313.00€
    2500µg
    2,057.00€
  • Sanguinarium Chloride

    CAS:
    <p>Stability Hygroscopic<br>Applications Sanguinarium Chloride is a natural product with antimicrobial, anti-inflammatory, and anti-oxidant properties. Sanguinarium Chloride has antiproliferative, pro-apoptosis effects in some cancer cell lines.<br>References Ahmad, N., et al.: Clin. Cancer Res., 6, 1524 (2000), Adhami, V., et al.: Mol. Cancer Ther., 3, 933 (2004),<br></p>
    Formula:C20H14NO4·Cl
    Color and Shape:Neat
    Molecular weight:367.78

    Ref: TR-S112500

    5mg
    130.00€
    10mg
    203.00€
    50mg
    711.00€
  • Sanguinarium chloride

    CAS:
    <p>Sanguinarium chloride is a bioactive compound, which is an alkaloid derived from plants of the Papaveraceae family, particularly the bloodroot (Sanguinaria canadensis). This compound exhibits its mode of action primarily through its ability to disrupt cellular processes by binding to DNA and interfering with the transcriptional machinery of microbes and existing as an antimicrobial agent. Furthermore, Sanguinarium chloride has shown inhibitory effects on bacterial proliferation, making it of interest in the development of antimicrobial and antiplaque products.</p>
    Formula:C20H14ClNO4
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:367.78 g/mol

    Ref: 3D-FS27791

    25mg
    239.00€
    50mg
    350.00€
    100mg
    501.00€
    250mg
    841.00€
    500mg
    1,302.00€