CAS 5578-98-3

5-Methyl-5-phenylpyrrolidin-2-one

CAS: 5578-98-3

5-Methyl-5-phenylpyrrolidin-2-one (MPP+) is an analog of butyric acid and the active substance in the neurotoxin MPTP. MPP+ causes death by inhibiting dopamine production, leading to Parkinson's disease. It also inhibits GABA synthesis and activates glutamate receptors. MPP+ has been shown to be toxic to rat brain cells in culture, causing neuronal degeneration. Injection of rats with MPP+ leads to decreased reflexes and a decrease in γ-aminobutyric acid (GABA) concentrations in the brain.

Formula: C₁₁H₁₃NO

Purity: Min. 95%

Molecular weight: 175.23 g/mol

Ref: 3D-FAA57898