CAS 55837-27-9

Piretanide

Description:

Piretanide is a pharmaceutical compound classified as a loop diuretic, primarily used in the management of edema associated with heart failure and other conditions. Its mechanism of action involves the inhibition of the sodium-potassium-chloride co-transporter in the thick ascending limb of the loop of Henle in the kidneys, leading to increased excretion of sodium, chloride, and water. This diuretic effect helps reduce fluid overload and lower blood pressure. Piretanide is known for its rapid onset of action and relatively short duration, making it effective for acute situations. The compound is typically administered orally and is characterized by its solubility in water, which facilitates its absorption in the gastrointestinal tract. As with other diuretics, potential side effects may include electrolyte imbalances, dehydration, and renal function impairment. It is essential for patients to be monitored for these effects during treatment. Overall, Piretanide is an important therapeutic agent in the management of fluid retention and hypertension.

Formula: C₁₇H₁₈N₂O₅S

InChI: InChI=1S/C17H18N2O5S/c18-25(22,23)15-11-12(17(20)21)10-14(19-8-4-5-9-19)16(15)24-13-6-2-1-3-7-13/h1-3,6-7,10-11H,4-5,8-9H2,(H,20,21)(H2,18,22,23)

InChI key: InChIKey=UJEWTUDSLQGTOA-UHFFFAOYSA-N

SMILES: O(C1=C(C=C(C(O)=O)C=C1S(N)(=O)=O)N2CCCC2)C3=CC=CC=C3

Synonyms:

• 3-(Aminosulfonyl)-4-phenoxy-5-(1-pyrrolidinyl)benzoic acid
• 4-Phenoxy-3-(Pyrrolidin-1-Yl)-5-Sulfamoylbenzoic Acid
• 4-Phenoxy-3-(pyrrolidinyl)-5-sulfamoylbenzoic acid
• Arelix
• Arlix
• Benzoic acid, 3-(aminosulfonyl)-4-phenoxy-5-(1-pyrrolidinyl)-
• Diumax
• Eurelix
• Hoe 118
• S 73-4118
• Tauliz

PIRETANIDE FOR SYSTEM SUITABILITY CRS

CAS: 55837-27-9

PIRETANIDE FOR SYSTEM SUITABILITY CRS

Formula: C₁₇H₁₈N₂O₅S

Molecular weight: 362.4002

Ref: 41-Y0001458

PIRETANIDE CRS

CAS: 55837-27-9

PIRETANIDE CRS

Formula: C₁₇H₁₈N₂O₅S

Color and Shape: White. Yellow. Powder.

Molecular weight: 362.4002

Ref: 41-P2120000

4-phenoxy-3-(pyrrolidin-1-yl)-5-sulfamoylbenzoic acid

CAS: 55837-27-9

Formula: C₁₇H₁₈N₂O₅S

Purity: 99%

Color and Shape: Solid

Molecular weight: 362.4002

Ref: IN-DA00I9YT

Piretanide

CAS: 55837-27-9

Formula: C₁₇H₁₈N₂O₅S

Molecular weight: 362.40

Ref: 7W-GP6474

Piretanide

CAS: 55837-27-9

Piretanide, an oral loop diuretic, effective and potassium-sparing, heart failure and hypertension with reduced electrolyte imbalance risk.

Formula: C₁₇H₁₈N₂O₅S

Color and Shape: Pale Yellow Powder

Molecular weight: 362.4

Ref: TM-T19788

Piretanide

CAS: 55837-27-9

Formula: C₁₇H₁₈N₂O₅S

Molecular weight: 362.40

Ref: 4Z-P-262001

Piretanide

CAS: 55837-27-9

Applications High-ceiling loop diuretic; structurally related to Bumetanide (B689550). Diuretic.
References Merkel, W., et al.: Eur. J. Med. Chem., 11, 399 (1976), Pozet, N., et al.: Br. J. Clin. Pharmacol., 9, 577 (1980), Clissold, S.P., et al.: Drugs, 29, 489 (1985),

Formula: C₁₇H₁₈N₂O₅S

Color and Shape: Light Yellow Solid

Molecular weight: 362.40

Ref: TR-P508700