CAS 5585-59-1

nitrocycline

Description:

Nitrocycline, with the CAS number 5585-59-1, is a synthetic antibiotic belonging to the tetracycline class of compounds. It is characterized by its broad-spectrum antibacterial activity, which makes it effective against a variety of Gram-positive and Gram-negative bacteria. Nitrocycline functions by inhibiting bacterial protein synthesis, thereby preventing the growth and reproduction of bacteria. The compound is typically administered in its hydrochloride form and is known for its stability in acidic environments, which enhances its bioavailability. In addition to its antibacterial properties, nitrocycline has been studied for its potential anti-inflammatory effects. However, like other tetracyclines, it may cause side effects such as gastrointestinal disturbances and photosensitivity. Nitrocycline is not commonly used in clinical practice today, as newer antibiotics with improved efficacy and safety profiles have emerged. Its use is more prevalent in veterinary medicine, particularly in the treatment of infections in livestock. As with all antibiotics, the development of resistance is a concern, necessitating careful consideration of its use in both human and veterinary medicine.

Formula: C₂₁H₂₁N₃O₉

InChI: InChI=1/C21H21N3O9/c1-23(2)15-9-6-7-5-8-10(24(32)33)3-4-11(25)13(8)16(26)12(7)18(28)21(9,31)19(29)14(17(15)27)20(22)30/h3-4,7,9,15,25,27-28,31H,5-6H2,1-2H3,(H2,22,30)/t7-,9-,15-,21-/m0/s1

Synonyms:

• Nitrocycline [USAN:INN]
• 4-(Dimethylamino)-1,3,3a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-nitro-1,11-dioxo-2-naphthacene-carboxamide
• UNII-2JH9LR1Y6S
• 7-Nitro-6-demethyl-6-deoxytetracycline
• Nitrocyclina
• Nitrocyclinum
• 4beta-Dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12abeta-tetrahydroxy-7-nitro-1,11-dioxo-2-naphthacencarboxamid
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-nitro-1,11-dioxo-, (4S-(4alpha,4aalpha,5aalpha,12aalpha))-
• Nitrocycline
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-7-nitro-1,11-dioxo-, (4S,4aS,5aR,12aS)-
• (2Z,4S,4aS,5aR,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-10,11,12a-trihydroxy-7-nitro-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione

Nitrocycline

CAS: 5585-59-1

Nitrocycline is a broad-spectrum antibiotic, which is a synthetic derivative of tetracycline with enhanced antibacterial properties. As a chemically synthesized compound, nitrocycline has been engineered to overcome resistance mechanisms common in bacterial pathogens. Its mode of action involves the inhibition of protein synthesis, achieved by binding to the 30S ribosomal subunit, effectively preventing the addition of new amino acids to nascent peptide chains. This binding action interrupts bacterial growth and replication, providing robust activity against both Gram-positive and Gram-negative bacteria.

Formula: C₂₁H₂₁N₃O₉

Purity: Min. 95%

Molecular weight: 459.4 g/mol

Ref: 3D-FN181101

7-Nitrosancycline

CAS: 5585-59-1

Formula: C₂₁H₂₁N₃O₉

Molecular weight: 459.41

Ref: ST-EA-CP-M54023