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CAS 55852-84-1

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Bacitracin methylenedisalicylate

Description:
Bacitracin methylenedisalicylate is a complex chemical compound derived from bacitracin, which is a polypeptide antibiotic produced by the bacterium Bacillus subtilis. This substance is primarily used for its antibacterial properties, particularly in topical applications. It exhibits a broad spectrum of activity against Gram-positive bacteria and some Gram-negative bacteria, making it valuable in treating skin infections and preventing bacterial growth in various formulations. The methylenedisalicylate component enhances its stability and solubility, facilitating its use in pharmaceutical preparations. Bacitracin methylenedisalicylate is typically administered topically and is known for its low toxicity profile, although allergic reactions can occur in sensitive individuals. Its mechanism of action involves inhibiting bacterial cell wall synthesis, which ultimately leads to cell lysis and death. In addition to its antimicrobial properties, it may also possess anti-inflammatory effects, contributing to its efficacy in wound healing. As with any antibiotic, appropriate usage is essential to prevent the development of resistance.
Formula:C15H12O6·Unspecified
InChI:InChI=1/C66H105N17O17S.C15H12O6/c1-9-35(6)52(70)65-81-48(32-101-65)62(96)76-43(26-34(4)5)58(92)74-42(22-23-50(85)86)57(91)83-53(36(7)10-2)63(97)75-40(20-15-16-24-67)55(89)73-41(21-17-25-68)56(90)82-54(37(8)11-3)64(98)79-44(27-38-18-13-12-14-19-38)59(93)77-45(28-39-31-71-33-72-39)60(94)78-46(30-51(87)88)61(95)80-47(66(99)100)29-49(69)84;16-12-7-3-1-5-10(12)14(18)20-9-21-15(19)11-6-2-4-8-13(11)17/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67-68,70H2,1-8H3,(H2,69,84)(H,71,72)(H,73,89)(H,74,92)(H,75,97)(H,76,96)(H,77,93)(H,78,94)(H,79,98)(H,80,95)(H,82,90)(H,83,91)(H,85,86)(H,87,88)(H,99,100);1-8,16-17H,9H2/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46+,47-,48?,52?,53-,54-;/m0./s1
Synonyms:
  • Methylenebis(2-hydroxybenzoate)bacitracin
  • Bacitracin, methylenebis(2-hydroxybenzoate) (salt)
  • Bacitracin, methylenebis[2-hydroxybenzoate]
  • bacitracin methylenedisalicylic acid
  • Caswell No. 066D
  • ALTRACIN
  • BMD
  • BACIDRIN
  • Bacitracin methylenedisalicylate
  • Bacitracin, compd. with methylenedisalicylic acid
  • See more synonyms
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