CAS 55854-46-1

5-Bromo-2-thiophenesulfonyl chloride

Description:

5-Bromo-2-thiophenesulfonyl chloride is an organic compound characterized by its thiophene ring structure, which is a five-membered aromatic heterocycle containing sulfur. The presence of a bromine atom at the 5-position and a sulfonyl chloride group at the 2-position contributes to its reactivity and utility in various chemical reactions. This compound is typically a solid at room temperature and is known for its ability to act as a sulfonating agent, making it valuable in synthetic organic chemistry, particularly in the preparation of sulfonamide derivatives and other functionalized thiophenes. It is important to handle this compound with care due to its reactive nature, especially the sulfonyl chloride group, which can react with water and amines, releasing hydrochloric acid. Additionally, it may exhibit moderate toxicity, necessitating appropriate safety precautions during handling and use. Overall, 5-Bromo-2-thiophenesulfonyl chloride serves as a versatile building block in the synthesis of various chemical entities in research and industrial applications.

Formula: C₄H₂BrClO₂S₂

InChI: InChI=1S/C4H2BrClO2S2/c5-3-1-2-4(9-3)10(6,7)8/h1-2H

InChI key: InChIKey=WGYBIEOLAFYDEC-UHFFFAOYSA-N

SMILES: S(Cl)(=O)(=O)C=1SC(Br)=CC1

Synonyms:

• 2-Thiophenesulfonyl chloride, 5-bromo-
• 5-Bromo-2-thiophenesulfonyl chloride
• 5-Bromo-thiophene-2-sulfonyl chloride
• 5-Bromothiophene-2-Sulfonylchloride
• 5-Bromothiophene-2-Sulphonyl Chloride
• 5-Bromothiophene-2-sulfonyl chloride

2-​Thiophenesulfonyl chloride, 5-​bromo-

CAS: 55854-46-1

Formula: C₄H₂BrClO₂S₂

Purity: 97%

Color and Shape: Liquid

Molecular weight: 261.5445

Ref: IN-DA003ML9

5-Bromothiophene-2-sulfonyl chloride

CAS: 55854-46-1

Formula: C₄H₂BrClO₂S₂

Molecular weight: 261.55

Ref: 7W-GK4601

5-Bromothiophene-2-sulphonyl chloride

CAS: 55854-46-1

5-Bromothiophene-2-sulphonyl chloride

Formula: C₄H₂BrClO₂S₂

Purity: 96%

Color and Shape: faint brown/beige crystalline solid

Molecular weight: 261.54g/mol

Ref: 54-OR9008

5-Bromothiophene-2-sulfonyl chloride

CAS: 55854-46-1

Formula: C₄H₂BrClO₂S₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 261.53

Ref: 10-F005201

5-Bromo-2-thiophenesulfonyl chloride

CAS: 55854-46-1

5-Bromo-2-thiophenesulfonyl chloride (5BrTSCl) is a chemical compound that belongs to the class of matrix metalloproteinase inhibitors. This drug inhibits the activity of MMPs and has anticancer activity. 5BrTSCl blocks the activation of MMPs by binding to their active site, which prevents the cleavage of collagen and other proteins. It also inhibits cell proliferation in a number of cancer cell lines, including human breast cancer cells. 5BrTSCl has been shown to be effective in inhibiting angiogenesis and tumor growth in animal models.

Formula: C₄H₂BrClO₂S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 261.55 g/mol

Ref: 3D-FB03112

5-Bromothiophene-2-sulfonyl chloride, 96%

CAS: 55854-46-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Formula: C₄H₂BrClO₂S₂

Purity: 96%

Color and Shape: Crystals or powder or crystalline powder, Pale cream to cream to yellow to dark yellow

Molecular weight: 261.53

Ref: 02-A14677