CAS 55869-99-3

Anisodamine

Description:

Anisodamine, with the CAS number 55869-99-3, is a chemical compound that belongs to the class of tropane alkaloids. It is primarily derived from the plant Anisodus tanguticus and exhibits anticholinergic properties, which means it can inhibit the action of acetylcholine at muscarinic receptors. This characteristic makes anisodamine useful in various medical applications, particularly in treating conditions such as bradycardia and certain types of shock. The compound is known for its ability to induce vasodilation and improve blood circulation, which can be beneficial in managing cardiovascular issues. Anisodamine also has potential neuroprotective effects and may be explored for its role in treating neurological disorders. Its chemical structure features a tropane ring, which is typical of many alkaloids, contributing to its biological activity. As with many pharmacological agents, the safety profile, dosage, and potential side effects of anisodamine should be carefully considered in clinical settings.

Formula: C₁₇H₂₃NO₄

InChI: InChI=1S/C17H23NO4/c1-18-12-7-13(9-15(18)16(20)8-12)22-17(21)14(10-19)11-5-3-2-4-6-11/h2-6,12-16,19-20H,7-10H2,1H3/t12-,13-,14+,15+,16-/m0/s1

InChI key: InChIKey=WTQYWNWRJNXDEG-RBZJEDDUSA-N

SMILES: CN1[C@]2([C@@H](O)C[C@@]1(C[C@H](OC([C@H](CO)C3=CC=CC=C3)=O)C2)[H])[H]

Synonyms:

• (-)-(3S,6S,2′S)-6β-Hydroxyhyoscyamine
• (-)-6β-Hydroxyhyoscyamine
• 6-Hydroxyhyoscyamine
• Anisodamine
• Benzeneacetic acid, α-(hydroxymethyl)-, (1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-
• Benzeneacetic acid, α-(hydroxymethyl)-, 6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [1R-[1α,3β(S*),5α,6α]]-
• Bicyclo[3.2.1]Oct-3-Yl 3-Hydroxy-2-Phenylpropanoate
• Bicyclo[3.2.1]oct-3-yl tropate
• Hyoscyamine, 6-hydroxy-
• (αS)-α-(Hydroxymethyl)benzeneacetic acid (1R,5R)-6β-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3α-yl ester
• 6-hydroxy-hyoscyamin
• Hyoscyamine, 6-hydroxy-(6ci, 7ci)
• aceanisodaMine
• alpha-(hydroxymethyl)-benzeneaceticaci6-hydroxy-8-methyl-8-azabicyclo(3.2
• (1r-(1-alpha,3-beta(s*),5-alpha,6-alpha))-.1)oct-3-yleste
• alpha-(Hydroxymethyl)benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester
• (αS)-α-(Hydroxymethyl)benzeneacetic acid (1R,5R)-6β-hydroxy-8-methyl-8-azabicyclo[3.2.1]octa-3α-yl ester
• Benzeneacetic acid, alpha-(hydroxymethyl)-, 6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, (1R-(1-alpha,3-beta(S*),5-alpha,6-alpha))-
• (αS)-α-Hydroxymethylbenzeneacetic acid (1β,5β)-6β-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-3α-yl ester
• Atropine iMpurity E (7-hydroxyhyoscyaMine)
• Benzeneacetic acid, alpha-(hydroxymethyl)-, (1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, (alphas)-
• [S,(-)]-α-(Hydroxymethyl)benzeneacetic acid (1R,5R)-6β-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-3α-yl ester

[(1S,3S,5S,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate

CAS: 55869-99-3

Formula: C₁₇H₂₃NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 305.3688

Ref: IN-DA01DNA6

Atropine EP Impurity D and E (Mixture of 6-β-Hydroxyhyoscyamine and 7-β-Hydroxyhyoscyamine)

CAS: 126371-43-5, 55869-99-3

Formula: C₁₇H₂₃NO₄

Color and Shape: White To Off-White Solid

Molecular weight: 305.37

Ref: 4Z-A-151007

Anisodamine

CAS: 55869-99-3

Anisodamine

Purity: ≥98%

Molecular weight: 305.37g/mol

Ref: 54-BUP12119

6-Hydroxyhyoscyamine (Mixture of Diastereomers)

CAS: 126371-43-5, 55869-99-3

Stability Hygroscopic
Applications Mixture of 6R-Hydroxyhyoscyamine (H942815) and 6S-Hydroxyhyoscyamine (H942820). A derivative of Hyoscyamine (H674300).

Formula: C₁₇H₂₃NO₄

Color and Shape: Neat

Molecular weight: 305.37

Ref: TR-H942900

6-Hydroxyhyoscyamine

CAS: 55869-99-3

6-Hydroxyhyoscyamine is a natural molecule that can bind to DNA. It has been shown to have high affinity for the 5'-GCAT-3' sequence and high specificity for the G-quadruplex structure. 6-Hydoxyhyoscyamine also has a phase transition temperature of 146°C, which may be due to the hydrogen bonds it forms with water molecules. It has been shown that 6-hydroxyhyoscyamine inhibits tumor cell growth by binding to a specific region of the promoter region of the gene encoding for growth factor β1 (GFβ1) and preventing transcription. This agent also has an inhibitory effect on tumor angiogenesis and vascular permeability, which may be related to its ability to inhibit nitric oxide production in endothelial cells. The compound is also known as anisodamine and can be used as an injection solution for patients who have had a myocardial infarct.

Formula: C₁₇H₂₃NO₄

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 305.37 g/mol

Ref: 3D-FH44857

Anisodamine

CAS: 55869-99-3

Anisodamine is similar to scopolamine & atropine, blocks muscarinic/nicotinic receptors, aids shock-related microcirculation & organophosphate studies.

Formula: C₁₇H₂₃NO₄

Purity: 98% - 98.16%

Color and Shape: Solid

Molecular weight: 305.37

Ref: TM-T21532

Atropine EP Impurity D

CAS: 55869-99-3

Formula: C₁₇H₂₃NO₄

Molecular weight: 305.37

Ref: ST-EA-CP-A206004