CAS 5588-16-9

Althiazide

Description:

Althiazide is a thiazide diuretic, primarily used in the management of hypertension and edema associated with various conditions, such as heart failure. It functions by inhibiting sodium reabsorption in the distal convoluted tubule of the nephron, leading to increased excretion of sodium and water, which helps to lower blood pressure and reduce fluid retention. The chemical structure of Althiazide includes a sulfonamide group, which is characteristic of thiazide diuretics, contributing to its pharmacological activity. It is typically administered orally and is known for its relatively long duration of action. Common side effects may include electrolyte imbalances, such as hypokalemia, and potential allergic reactions due to its sulfonamide component. Althiazide's efficacy and safety profile make it a widely prescribed medication in clinical practice, although it is essential for patients to be monitored for any adverse effects during treatment. As with all medications, it should be used under the guidance of a healthcare professional.

Formula: C₁₁H₁₄ClN₃O₄S₃

InChI: InChI=1S/C11H14ClN3O4S3/c1-2-3-20-6-11-14-8-4-7(12)9(21(13,16)17)5-10(8)22(18,19)15-11/h2,4-5,11,14-15H,1,3,6H2,(H2,13,16,17)

InChI key: InChIKey=VGLGVJVUHYTIIU-UHFFFAOYSA-N

SMILES: O=S1(=O)C=2C(NC(CSCC=C)N1)=CC(Cl)=C(S(N)(=O)=O)C2

Synonyms:

• 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-[(allylthio)methyl]-6-chloro-3,4-dihydro-, 1,1-dioxide
• 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-, 1,1-dioxide
• 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-[(2-propenylthio)methyl]-, 1,1-dioxide
• 3-[(Allylthio)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 6-chloro-3-[(prop-2-en-1-ylsulfanyl)methyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• Aldactazine
• Althizide
• Altizid
• Altizide
• P-1779
• Racemic althiazide

ALTIZIDE CRS

CAS: 5588-16-9

ALTIZIDE CRS

Formula: C₁₁H₁₄ClN₃O₄S₃

Molecular weight: 383.8946

Ref: 41-Y0000606

Altizide

CAS: 5588-16-9

Formula: C₁₁H₁₄ClN₃O₄S₃

Molecular weight: 383.88

Ref: 4Z-A-338001

Althiazide

CAS: 5588-16-9

Applications Diuretic and antihypertensive.
References Twagirumukiza, M., et al.: Trop. Med. Int. Health, 15, 350 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Peters, R., et al.: Anal. Bioanal. Chem., 396, 2583 (2010),

Formula: C₁₁H₁₄ClN₃O₄S₃

Color and Shape: Neat

Molecular weight: 383.89

Ref: TR-A575775

Altizide

CAS: 5588-16-9

Altizide is a thiazide diuretic. It is used to treat oedema and hypertension.

Formula: C₁₁H₁₄ClN₃O₄S₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 383.89

Ref: TM-T19646