CAS 55905-53-8

Clebopride

Description:

Clebopride is a synthetic compound classified as a benzamide derivative, primarily used for its antiemetic and prokinetic properties. It acts as a dopamine D2 receptor antagonist, which helps in the management of gastrointestinal disorders by enhancing gastric motility and reducing nausea and vomiting. Clebopride is often utilized in the treatment of conditions such as functional dyspepsia and gastroesophageal reflux disease (GERD). The substance is characterized by its ability to cross the blood-brain barrier, which can lead to central nervous system effects. Its pharmacological profile includes a relatively low incidence of extrapyramidal side effects compared to other dopamine antagonists. Clebopride is typically administered orally and is metabolized in the liver, with its excretion primarily occurring through urine. As with any medication, it is essential to consider potential side effects and contraindications, and its use should be guided by a healthcare professional.

Formula: C₂₀H₂₄ClN₃O₂

InChI: InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25)

InChI key: InChIKey=BVPWJMCABCPUQY-UHFFFAOYSA-N

SMILES: C(NC1CCN(CC2=CC=CC=C2)CC1)(=O)C3=C(OC)C=C(N)C(Cl)=C3

Synonyms:

• 259-885-9
• 4-Amino-5-chloro-2-methoxy-N-[1-(phenylmethyl)-4-piperidinyl]benzamide
• 4-Amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide
• 4-amino-N-(1-benzyl-4-piperidyl)-5-chloro-2-methoxy-benzamide
• 4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide (2Z)-but-2-enedioate
• Brl 20596
• Malonic Acid
• benzamide, 4-amino-5-chloro-2-methoxy-N-[1-(phenylmethyl)-4-piperidinyl]-
• Clebopride

Clebopride

CAS: 55905-53-8

Clebopride is antidopaminergic. Clebopride also has an effect of antiemetic.

Formula: C₂₀H₂₄ClN₃O₂

Color and Shape: Solid

Molecular weight: 373.88

Ref: TM-T7569L