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CAS 5593-20-4

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Betamethasone dipropionate

Description:
Betamethasone dipropionate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, primarily used in dermatological formulations to treat various skin conditions. It is characterized by its high potency and effectiveness in reducing inflammation and itching. The substance is a white to off-white crystalline powder, which is practically insoluble in water but soluble in organic solvents like ethanol and acetone. Its chemical structure features a steroid backbone with two propionate ester groups, enhancing its lipophilicity and skin penetration. Betamethasone dipropionate is often formulated in creams, ointments, and lotions for topical application, allowing for localized treatment with minimal systemic absorption. The compound is known for its relatively low risk of systemic side effects when used appropriately, although prolonged use can lead to skin atrophy and other local adverse effects. As with all corticosteroids, it is essential to use betamethasone dipropionate under medical supervision to mitigate potential risks and ensure effective treatment outcomes.
Formula:C28H37FO7
InChI:InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1
InChI key:InChIKey=CIWBQSYVNNPZIQ-XYWKZLDCSA-N
SMILES:C(COC(CC)=O)(=O)[C@]1(OC(CC)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]
Synonyms:
  • (11-beta,16-beta)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione-17,21-dipropionate
  • (11Beta,16Beta)-9-Fluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Diene-17,21-Diyl Dipropanoate
  • (11β,16β)-9-Fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione
  • (8Xi,9Xi,11Beta,14Xi,16Beta)-9-Fluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Diene-17,21-Diyl Dipropanoate
  • (9Ξ,11Β,16Β)-17-[(Chloroacetyl)Oxy]-9-Fluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Propanoate
  • 1,4-Pregnadien-9-Alpha-Fluoro-16-Beta-Methyl-11-Beta, 17,21-Triol-3,20-Dione 17,21-Dipropionate
  • 9--Fluoro-16--methyl-11,17,21-trihydroxy-1,4-pregnadiene-3,20-dione17,21-dipropionate
  • 9-Fluoro-11Beta,17,21-Trihydroxy-16Beta-Methylpregna-1,4-Diene-3,20-Dione 17,21-Di(Propionate)
  • 9A-Fluoro-16B-Methyl-11B,17A,21-Trihydroxy-1,4-Pregnadiene-3,20-Dione 17,21-Dipropionate
  • 9Alpha-Fluoro-16Beta-Methyl-11Beta,17Alpha,21-Trihydroxy-1,4-Pregnadiene-3,20-Dione 17,21-Dipropionate
  • See more synonyms
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  • Betamethasone 17,21-dipropionate
    Biosynth
    + Info

    Betamethasone 17,21-dipropionate

    Controlled Product
    CAS:
    <p>Betamethasone 17,21-dipropionate is a potent synthetic corticosteroid, which is derived from corticosteroids found naturally in the adrenal cortex. It functions primarily as an anti-inflammatory and immunosuppressive agent by modulating the expression of inflammatory mediators. Specifically, it binds to glucocorticoid receptors, altering gene transcription and inhibiting the migration of leukocytes to sites of inflammation. This results in reduced synthesis of inflammatory cytokines and decreased swelling, redness, and pain.</p>
    Formula:C28H37FO7
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:504.59 g/mol

    Ref: 3D-FB36997

    1g
    200.00€
    2g
    315.00€
    5g
    538.00€
    10g
    793.00€
    25g
    1,067.00€