CAS 5598-15-2

Chlorpyrifos oxon

Description:

Chlorpyrifos oxon, with the CAS number 5598-15-2, is an organophosphate compound that serves as a potent insecticide and is a metabolite of chlorpyrifos. It is characterized by its ability to inhibit acetylcholinesterase, an enzyme critical for the proper functioning of the nervous system in insects, leading to paralysis and death. This compound is typically a colorless to pale yellow liquid with a faint odor, and it is soluble in organic solvents but has limited solubility in water. Chlorpyrifos oxon is known for its high toxicity to a variety of non-target organisms, including humans, which has raised significant environmental and health concerns. Its persistence in the environment can lead to bioaccumulation in the food chain. Regulatory agencies in various countries have imposed restrictions or bans on its use due to its potential adverse effects on human health and ecosystems. Proper handling and application are crucial to mitigate risks associated with exposure to this chemical.

Formula: C₉H₁₁Cl₃NO₄P

InChI: InChI=1S/C9H11Cl3NO4P/c1-3-15-18(14,16-4-2)17-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3

InChI key: InChIKey=OTMOUPHCTWPNSL-UHFFFAOYSA-N

SMILES: P(OC1=C(Cl)C=C(Cl)C(Cl)=N1)(OCC)(OCC)=O

Synonyms:

• 2-Pyridinol, 3,5,6-trichloro-, diethyl phosphate (ester)
• 3,5,6-Trichloro-2-pyridyl diethyl phosphate
• Chloropyrifos oxon
• Chlorpyrifos oxon
• Chlorpyrifos-ethyl oxon
• Chlorpyrifoxon
• Chlorpyriphoxon
• Diethyl 3,5,6-trichloro-2-pyridinyl phosphate
• Diethyl 3,5,6-trichloro-2-pyridyl phosphate
• Diethyl-3,5,6-trichlor-2-pyridinylphosphat
• Dursban oxygen analog
• Dursbanoxon
• Fospirate-ethyl
• O,O-Diethyl O-3,5,6-trichloro-2-pyridyl phosphate
• O-(3,5,6-Trichloro-2-pyridinyl) O,O-diethyl phosphate
• Phosphate de diéthyle et de 3,5,6-trichloro-2-pyridinyle
• Phosphoric Acid, Diethyl 3,5,6-Trichloro-2-Pyridinyl Ester
• Phosphoric acid, diethyl 3,5,6-trichloro-2-pyridinyl ester (9CI)

Chlorpyrifos-oxon

Controlled Product

CAS: 5598-15-2

Formula: C₉H₁₁Cl₃NO₄P

Color and Shape: Neat

Molecular weight: 334.52

Ref: 04-C11603000

Chlorpyrifos Oxon

CAS: 5598-15-2

Formula: C₉H₁₁Cl₃NO₄P

Molecular weight: 334.51

Ref: 4Z-C-234

Chlorpyrifos Oxon

Controlled Product

CAS: 5598-15-2

Stability Moisture Sensitive
Applications Chlorpyrifos Oxon is a metabolite of Chlorpyrifos (C425300) in human.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Atterberry, T., et al.: Toxicol. Appl. Pharmacol., 147, 411 (1997), Karanth, S., et al.: Toxicol. Sci., 58, 282 (2000), Barter, Z., et al.: Drug Metab. Dispos., 36, 2405 (2008),

Formula: C₉H₁₁Cl₃NO₄P

Color and Shape: Off-White

Molecular weight: 334.52

Ref: TR-C425320

Chlorpyrifos-oxon

CAS: 5598-15-2

Chlorpyrifos-oxon, an active metabolite of Chlorpyrifos, is a potent phosphorylating agent that significantly inhibits AChE activity and induces cross-linking between tubulin subunits, thereby disrupting microtubule function [4].

Formula: C₉H₁₁Cl₃NO₄P

Color and Shape: Solid

Molecular weight: 334.52

Ref: TM-T40642

Chlorpyrifos oxon

CAS: 5598-15-2

Chlorpyrifos oxon is a site-specific acetylcholinesterase inhibitor that is used as a sample preparation chemical for the analysis of fatty acids, hydroxyl groups, and pharmacological agents. Chlorpyrifos oxon can be used to study the effects of sublethal doses on probiotic bacteria. It has been found that chlorpyrifos oxon inhibits the activity of human serum acetylcholinesterase by binding to its active site with high affinity. The inhibition of acetylcholinesterase by chlorpyrifos oxon prevents the hydrolysis of acetylcholine at cholinergic synapses in the brain and peripheral nervous system. This leads to accumulation of acetylcholine and an increase in stimulation of postsynaptic receptors, resulting in increased transmission across neuronal synapses. Chlorpyrifos oxon also is known to have immunomodulatory properties and has been shown to stimulate

Formula: C₉H₁₁Cl₃NO₄P

Purity: Min. 95%

Molecular weight: 334.52 g/mol

Ref: 3D-FC20412