CAS 55981-09-4: Nitazoxanide

Description: Nitazoxanide is an antiparasitic and antiviral compound primarily used in the treatment of various infections, including those caused by protozoa and certain viruses. It is classified as a thiazolide and exhibits a broad spectrum of activity against a range of pathogens. The chemical structure of nitazoxanide features a thiazole ring, which contributes to its pharmacological properties. It works by inhibiting the enzyme pyruvate:ferredoxin oxidoreductase, disrupting the energy metabolism of the target organisms. Nitazoxanide is typically administered orally and is known for its relatively low toxicity profile. It is often used in combination with other medications to enhance therapeutic efficacy. The compound is also being investigated for its potential use against various viral infections, including influenza and coronaviruses. Its solubility and stability in different pH environments make it suitable for formulation in various dosage forms. Overall, nitazoxanide represents a significant advancement in the treatment of infectious diseases, showcasing the importance of chemical compounds in modern medicine.

Formula: C₁₂H₉N₃O₅S

InChI: InChI=1S/C12H9N3O5S/c1-7(16)20-9-5-3-2-4-8(9)11(17)14-12-13-6-10(21-12)15(18)19/h2-6H,1H3,(H,13,14,17)

InChI key: InChIKey=YQNQNVDNTFHQSW-UHFFFAOYSA-N

SMILES: O=C(OC=1C=CC=CC1C(=O)NC2=NC=C(S2)N(=O)=O)C

Synonyms:

• 2-(Acetyloxy)-N-(5-nitro-2-thiazolyl)benzamide
• 2-[(5-Nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate
• Alinia
• Brn 1225475
• Cryptaz
• Daxon
• Dexidex
• Drg 0242
• Kidonax
• Mitafar
• N-(5-Nitro-2-thiazolyl)salicylamide acetate (ester)
• NTX
• NTZ
• Nitacure
• Nitacure 500
• Nitarid
• Nitazode
• Nitazox 500
• Nitazoxanida
• Nitazoxanide
• Nixide
• Nixoran
• Nizonide
• Nsc 697855
• Pacovanton
• ParaMix
• Ph 5776
• Xerovirin-C
• acetate de o-[N-(5-nitrothiazole-2-yl)carbamoyl]phenyle
• acetato de o-[N-(5-nitrotiazol-2-il)carbamoil]fenilo
• o-[N-(5-Nitrothiazol-2-yl)carbamoyl]phenylacetat
• o-[N-(5-nitrothiazol-2-yl)carbamoyl]phenyl acetate
• Benzamide, 2-(acetyloxy)-N-(5-nitro-2-thiazolyl)-

Nitazoxanide

CAS: 55981-09-4

Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure

• Formula: C₁₂H₉N₃O₅S
• Color and Shape: Light Yellow Yellow Powder
• Molecular weight: 307.02629

Nitazoxanide

CAS: 55981-09-4

Nitazoxanide (NSC-697855) is a synthetic benzamide antiprotozoal; it disrupts pyruvate electron transfer reactions.

• Formula: C₁₂H₉N₃O₅S
• Purity: 97.20% - 99.53%
• Color and Shape: Solid
• Molecular weight: 307.28

Benzamide, 2-(acetyloxy)-N-(5-nitro-2-thiazolyl)-

CAS: 55981-09-4

• Formula: C₁₂H₉N₃O₅S
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 307.28196

Nitazoxanide

CAS: 55981-09-4

• Purity: 99%
• Molecular weight: 307.28g/mol

Nitazoxanide

CAS: 55981-09-4

• Purity: 99%
• Molecular weight: 307.28g/mol

Nitazoxanide

CAS: 55981-09-4

• Formula: C₁₂H₉N₃O₅S
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Orange to Green powder to crystal
• Molecular weight: 307.28

Nitazoxanide

CAS: 55981-09-4

• Formula: C₁₂H₉N₃O₅S
• Color and Shape: Neat
• Molecular weight: 307.28

Nitrazoxanide

CAS: 55981-09-4

• Formula: C₁₂H₉N₃O₅S
• Color and Shape: Neat
• Molecular weight: 307.28

Nitazoxanide

CAS: 55981-09-4

• Formula: C₁₂H₉N₃O₅S
• Molecular weight: 307.28

Nitazoxanide

CAS: 55981-09-4

Applications An anthelmintic (cestodes), antiprotozoal (cryptosporidium). Kills Mycobacterium tuberculosis. References Cavier, R., et al.: Eur. …

• Formula: C₁₂H₉N₃O₅S
• Color and Shape: Light Yellow Crystalline
• Molecular weight: 307.28

Nitazoxanide

CAS: 55981-09-4

• Purity: 95.0%
• Color and Shape: Liquid, Crystalline Powder or Powder
• Molecular weight: 307.2799987792969

Nitazoxanide - Bio-X ™

CAS: 55981-09-4

Nitazoxanide acts as a noncompetitive inhibitor of the pyruvate: ferredoxin/flavodoxin oxidoreductases of various microorganism with …

• Formula: C₁₂H₉N₃O₅S
• Purity: Min. 90 Area-%
• Color and Shape: Powder
• Molecular weight: 307.28 g/mol

Nitazoxanide

CAS: 55981-09-4

Inhibitor of pyruvate oxidoreductases; inhibitor of viral replication.

• Formula: C₁₂H₉N₃O₅S
• Purity: Min. 98 Area-%
• Color and Shape: White Slightly Yellow Powder
• Molecular weight: 307.28 g/mol