CAS 56-09-7

2-Amino-6-hydroxy-4(3H)-pyrimidinone

Description:

2-Amino-6-hydroxy-4(3H)-pyrimidinone, also known as allopurinol, is a heterocyclic organic compound characterized by its pyrimidine ring structure, which contains both amino and hydroxy functional groups. This compound is primarily recognized for its role as a xanthine oxidase inhibitor, making it significant in the treatment of gout and certain types of kidney stones by reducing uric acid production. It is typically a white to off-white crystalline powder, soluble in water and alcohol, and exhibits a melting point that varies depending on purity. The presence of the amino and hydroxy groups contributes to its reactivity and biological activity. In terms of safety, it is essential to handle this compound with care, as it can cause side effects in some individuals, including allergic reactions. Overall, 2-Amino-6-hydroxy-4(3H)-pyrimidinone is an important pharmaceutical agent with specific therapeutic applications, particularly in managing hyperuricemia.

Formula: C₄H₅N₃O₂

InChI: InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)

InChI key: InChIKey=AUFJTVGCSJNQIF-UHFFFAOYSA-N

SMILES: O=C1C=C(O)N=C(N)N1

Synonyms:

• 2-Amino-4,6-dihydroxypyridimine
• 2-Amino-4,6-dioxypyrimidine
• 2-Amino-4,6-pyrimidinediol
• 2-Amino-4,6-pyrimidinedione
• 2-Amino-4-hydroxy-1H-pyrimidin-6-one
• 2-Amino-6-hydroxy-1,4-dihydropyrimidin-4-one
• 2-Amino-6-hydroxy-1H-pyrimidin-4-one
• 2-Amino-6-hydroxy-3H-pyrimidin-4-one
• 2-Amino-6-hydroxy-4(3H)-pyrimidinone
• 4(1H)-Pyrimidinone, 2-amino-6-hydroxy-
• 4(3H)-Pyrimidinone, 2-amino-6-hydroxy-
• 4,6-Dihydroxy-2-aminopyrimidine
• 4,6-Pyrimidinediol, 2-amino-
• NSC 15920
• NSC 18692

2-Amino-4,6-dihydroxypyrimidine, 98%

CAS: 56-09-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄H₅N₃O₂

Purity: 98%

Color and Shape: White to cream or pale yellow to pale pink, Powder

Molecular weight: 127.10

Ref: 02-A11813

2-Amino-4,6-dihydroxypyrimidine

CAS: 56-09-7

Formula: C₄H₅N₃O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 127.1014

Ref: IN-DA003GEO

2-Amino-4,6-dihydroxypyrimidine

CAS: 56-09-7

Formula: C₄H₅N₃O₂

Molecular weight: 127.10

Ref: 7W-GK3757

2-Amino-4,6-dihydroxypyrimidine

CAS: 56-09-7

Formula: C₄H₅N₃O₂

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow to Dark green powder to crystal

Molecular weight: 127.10

Ref: 3B-A1099

2-Amino-4,6-dihydroxypyrimidine

CAS: 56-09-7

2-Amino-4,6-dihydroxypyrimidine

Formula: C₄H₅N₃O₂

Purity: 98%

Color and Shape: yellow solid

Molecular weight: 127.1014g/mol

Ref: 54-OR11291

2-Amino-4,6-dihydroxypyrimidine-13C2

Controlled Product

CAS: 56-09-7

Applications 2-Amino-4,6-dihydroxypyrimidine-13C2 is an intermediate in the production of antimicrobial guanylsulfonamides.
References Barrett, O., et al.: ChemBioChem., 7, 1882 (2006), Patel, P., et al.: Bioorg. Med. Chem. Lett., 17, 6610 (2007), Gasser, L., et al.: Environ. Sci. Technol., 41, 2445 (2007)

Formula: C₂C₂H₅N₃O₂

Color and Shape: Neat

Molecular weight: 129.087

Ref: TR-A604932

2-Amino-4,6-dihydroxypyrimidine

CAS: 56-09-7

Formula: C₄H₅N₃O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 127.103

Ref: 10-F036340

2-Amino-4,6-dihydroxypyrimidine

CAS: 56-09-7

2-Amino-4,6-dihydroxypyrimidine is a chemical compound that is used in the synthesis of pemetrexed. It has been shown to inhibit the growth of cancer cells in cell culture by cross-coupling with nitrogen atoms in DNA and thereby inhibiting replication. 2-Amino-4,6-dihydroxypyrimidine also reacts with halides to form reaction intermediates that are capable of reacting with hydrogen bonds and other functional groups. This chemical compound has been shown to have radical scavenging activities in acidic environments and vibrational properties.

Formula: C₄H₅N₃O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 127.1 g/mol

Ref: 3D-FA17555