CAS 56-25-7

cantharidin

Description:

Cantharidin is a naturally occurring chemical compound classified as a terpenoid, primarily derived from the blister beetle species, particularly those in the genus Lytta. It is a colorless, odorless, and viscous liquid at room temperature, with a high boiling point and low solubility in water, but it is soluble in organic solvents. Cantharidin is known for its potent vesicant properties, meaning it can cause blistering of the skin upon contact. This compound has been historically used in traditional medicine for its purported therapeutic effects, including as a treatment for warts and other skin conditions. However, it is also recognized for its toxicity, which can lead to serious health issues if ingested or improperly handled. The mechanism of action involves the inhibition of protein phosphatases, which disrupts cellular processes. Due to its toxic nature, cantharidin is regulated in many jurisdictions, and its use is limited to specific medical applications under professional supervision.

Formula: C₁₀H₁₂O₄

InChI: InChI=1/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5?,6?,9-,10+

InChI key: InChIKey=DHZBEENLJMYSHQ-XCVPVQRUNA-N

SMILES: C[C@@]12[C@@](C)([C@@]3(O[C@]1(CC3)[H])[H])C(=O)OC2=O

Synonyms:

• (1R,2S,3R,6S)-1,2-Dimethyl-3,6-epoxycyclohexane-1,2-dicarboxylic anhydride
• (3aR,4R,7S,7aR)-3a,7a-dimethylhexahydro-4,7-epoxy-2-benzofuran-1,3-dione
• (3aR,4S,7R,7aS)-3a,7a-dimethylhexahydro-4,7-epoxy-2-benzofuran-1,3-dione
• (3aR,7aS)-3a,7a-dimethylhexahydro-4,7-epoxy-2-benzofuran-1,3-dione
• 1,2-Dimethyl-3,6-epoxyperhydrophthalic anhydride
• 3A,7A-Dimethylhexahydro-4,7-Epoxy-2-Benzofuran-1,3-Dione
• 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aR,4S,7R,7aS)-rel-
• 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aα,4β,7β,7aα)-
• 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride, 2,3-dimethyl-
• Canthacur
• Cantharides camphor
• Cantharidine
• Cantharone
• Dimethyl-3,6-epoxyperhydrophthalic anhydride
• Kantaridin
• NSC 61805
• exo-1,2-cis-Dimethyl-3,6-epoxyhexahydrophthalic anhydride
• rel-(3aR,4S,7R,7aS)-Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione
• Cantharidin
• (3A-ALPHA,4B,7B,7A-ALPHA)-HEXAHYDRO-3A,7A-DIMETHYL-4,7-EPOXYISOBENZOFURAN-1,3-DIONE
• 2,3-Dimethyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylicacidanhydride
• 2,3-Dimethyl-7-oxabicyclo(2.2.1)heptane-2,3-dicarboxylic anhydride
• 4,7-EPOXYISOBENZOFURAN-1,3-DIONE,HEXAHYDRO-3A,7A-DIMETHYL-, (3A,4,7,7A)-
• 1,2-dimethyl-3,6-epoxyperhydrophthalicanhydride
• (3AA,4B,7B,7AA)-HEXAHYDRO-3A,7A-DIMETHYL-4,7-EPOXYISOBENZOFURAN-1,3-DIONE
• 2,3-dimethyl-7-oxabicyclo(2.2.1)heptane-3-dicarboxylicanhydride
• 4,7-epoxyisobenzofuran-1,3-dione,hexahydro-3a,7a-dimethyl-,(3a-alpha,4-beta
• 4,7-epoxyisobenzofuran-1,3-dione,hexahydro-3a,7a-dimethyl-,(3aalpha,4beta,7be
• 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-
• 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aalpha,4beta,7beta,7aalpha)-
• HEXAHYDRO-3A,7A-DIMETHYL-4,7-EPOXYISOBENZO-FURAN-1,3-DIONE
• 7aalpha)-bet
• 2,3-dimethyl-7-oxabicyclo(2.2.1)heptane-2,3-dicarboxylicanhydride
• ,7-beta,7a-alpha)

Cantharidin

CAS: 56-25-7

Formula: C₁₀H₁₂O₄

Molecular weight: 196.20

Ref: 4Z-C-408001

Cantharidin

CAS: 56-25-7

Cantharidin

Purity: ≥98%

Molecular weight: 196.2g/mol

Ref: 54-BUP21429

Cantharidin

CAS: 56-25-7

Cantharidin, a natural toxin found in beetles in the families Meloidae and Oedemeridae, has been reported to be toxic to some pests, including the diamondback moth.

Formula: C₁₀H₁₂O₄

Purity: 99.41%

Color and Shape: Solid

Molecular weight: 196.20

Ref: TM-T2903

Cantharidin

CAS: 56-25-7

Formula: C₁₀H₁₂O₄

Purity: ≥ 98.0%

Color and Shape: Colourless crystals

Molecular weight: 196.20

Ref: 7W-GP7535

Cantharidin

CAS: 56-25-7

Cantharidin, a natural toxicant of blister beetles, is a strong inhibitor of protein phosphatases types 1 (PP1) and 2A (PP2A), and is a novel and potent multidrug resistance (MDR) reversal agent. Cantharidin has anti-tumor activity, it causes oxidative stress that provokes DNA damage and p53-dependent apoptosis, it impairs cell migration and invasion by suppressing MMP-2 and -9 through PI3K/NF-κB signaling pathways.

Formula: C₁₀H₁₂O₄

Purity: 95%~99%

Molecular weight: 196.202

Ref: BP-BP0309

Cantharidin

Controlled Product

CAS: 56-25-7

Formula: C₁₀H₁₂O₄

Color and Shape: Neat

Molecular weight: 196.20

Ref: 86-MM2534.00

Cantharidin

Controlled Product

CAS: 56-25-7

Formula: C₁₀H₁₂O₄

Color and Shape: Neat

Molecular weight: 196.20

Ref: 04-C10946750

Cantharidin

CAS: 56-25-7

Lactone

Formula: C₁₀H₁₂O₄

Purity: ≥ 98.0 % (GC)

Color and Shape: Powder

Molecular weight: 196.2

Ref: 5G-89594

Cantharidin

CAS: 56-25-7

Stability Hygroscopic
Applications Cantharidin is a well known natural compound produced by beetles of the Meloidae and Oedemeridae families. Insecticidal toxin. Apoptosis inducer in human H460 human lung cancer cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Khan, R. et al.: GMR. Gen. Mol. Res., 12, 4393 (2013); Hsia, T. et al.: Int. J. Onc., 45, 245 (2014);

Formula: C₁₀H₁₂O₄

Color and Shape: Neat

Molecular weight: 196.20

Ref: TR-C175630

Cantharidin

CAS: 56-25-7

Natural toxin; protein phosphatase inhibitor

Formula: C₁₀H₁₂O₄

Purity: Min. 98 Area-%

Color and Shape: White/Off-White Solid

Molecular weight: 196.2 g/mol

Ref: 3D-FC29633

Cantharidin

CAS: 56-25-7

Formula: C₁₀H₁₂O₄

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 196.20

Ref: 3B-C0019

Cantharidin, 98%

CAS: 56-25-7

Inhibitor of protein phosphatase 2A

Formula: C₁₀H₁₂O₄

Purity: 98%

Color and Shape: Powder

Molecular weight: 196.20

Ref: 02-J61801