CAS 56-47-3

Deoxycorticosterone acetate

Description:

Deoxycorticosterone acetate (DOCA) is a synthetic steroid hormone derived from the adrenal cortex, primarily functioning as a mineralocorticoid. It is characterized by its role in regulating electrolyte and water balance in the body, influencing sodium retention and potassium excretion. DOCA is typically administered in acetate form, which enhances its solubility and bioavailability. The compound has a molecular formula that reflects its steroid structure, featuring multiple rings and functional groups that contribute to its biological activity. It is often used in research and clinical settings to study adrenal function and hypertension. In terms of physical properties, DOCA is a white to off-white crystalline powder, relatively stable under standard conditions, and is soluble in organic solvents but less so in water. Its pharmacological effects can include increased blood pressure and fluid retention, making it significant in studies related to cardiovascular health and endocrine disorders. However, like other steroids, it may have side effects and requires careful dosage management.

Formula: C₂₃H₃₂O₄

InChI: InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1

InChI key: InChIKey=VPGRYOFKCNULNK-ACXQXYJUSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)(CC1)[H])[H])(CC[C@@H]2C(COC(C)=O)=O)[H]

Synonyms:

• (8Xi,9Xi,14Xi)-3,20-Dioxopregn-4-En-21-Yl Acetate
• 11-Deoxycorticosterone 21-acetate
• 11-Deoxycorticosterone, acetate
• 11-Desoxycorticosterone acetate
• 21-(Acetyloxy)pregn-4-ene-3,20-dione
• 21-Acetoxy-3,20-diketopregn-4-ene
• 21-Acetoxypregn-4-en-3,20-dione
• 21-Acetoxypregn-4-ene-3,20-dione
• 21-Acetyloxypregn-4-ene-3,20-dione
• 21-Hydroxypregn-4-ene-3,20-dione 21-acetate
• 21-Hydroxypregn-4-ene-3,20-dione acetate
• 3,20-Dioxopregn-4-En-21-Yl Acetate
• 4-Pregnene-3,20-dione 21-acetate
• 4-Pregnene-3,20-dione-21-ol acetate
• Acetate
• Acetate De Desoxycortone
• Acetato De Desoxicortona
• Arcort
• Bio-Corten
• Cortacet
• Cortate
• Cortenil
• Cortesan
• Cortexone acetate
• Cortifar
• Cortigen
• Cortinaq
• Cortiron
• Cortivis
• Cortixyl
• DCA
• DOC acetate
• Decorten
• Decortin
• Decosteron
• Decosterone
• Decostrate
• Deoxycorticosterone 21-acetate
• Deoxycorticosterone Acetate
• Deoxycortone acetate
• Descorterone
• Descotone
• Desoxycorticosterone Acetate
• Desoxycortonacetat
• Desoxycortone Acetate
• Doca
• Dorcostrin
• Doxo
• Doxycamon
• Krinocorts
• Nsc 9567
• Ocriten
• Ocritena
• Percorten
• Percotol
• Pregn-4-ene-3,20-dione, 21-(acetyloxy)-
• Pregn-4-ene-3,20-dione, 21-hydroxy-, acetate
• Primocort
• Primocortan
• Sincortex
• Steraq
• Syncort
• Syncorta
• Syncortyl

Deoxycorticosterone Acetate

CAS: 56-47-3

Formula: C₂₃H₃₂O₄

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 372.51

Ref: 3B-D0047

DESOXYCORTONE ACETATE CRS

CAS: 56-47-3

DESOXYCORTONE ACETATE CRS

Formula: C₂₃H₃₂O₄

Color and Shape: Added Modified

Molecular weight: 372.4978

Ref: 41-D0400000

Desoxycorticosterone Acetate

CAS: 56-47-3

Adrenal cortical hormones and their derivatives nesoi

Formula: C₂₃H₃₂O₄

Color and Shape: White Powder

Molecular weight: 372.23006

Ref: 45-1174001

Deoxycorticosterone Acetate

CAS: 56-47-3

Deoxycorticosterone Acetate

Purity: 99%

Molecular weight: 372.5g/mol

Ref: 54-OR1028220

Deoxycorticosterone acetate

CAS: 56-47-3

Deoxycorticosterone acetate

Purity: ≥98%

Molecular weight: 372.5g/mol

Ref: 54-BUP14773

Desoxycortone Acetate

Controlled Product

CAS: 56-47-3

Formula: C₂₃H₃₂O₄

Color and Shape: Neat

Molecular weight: 372.50

Ref: 86-MM1685.00

Deoxycorticosterone acetate

CAS: 56-47-3

Deoxycorticosterone acetate (Cortexone acetate) is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection.

Formula: C₂₃H₃₂O₄

Purity: 99% - >99.99%

Color and Shape: White Solid

Molecular weight: 372.50

Ref: TM-T3033

11-Deoxy Corticosterone Acetate

CAS: 56-47-3

Formula: C₂₃H₃₂O₄

Molecular weight: 372.51

Ref: 4Z-C-10417

Desoxycorticosterone Acetate

CAS: 56-47-3

Formula: C₂₃H₃₂O₄

Molecular weight: 372.5

Ref: ST-EA-CP-D124000

Deoxy corticosterone acetate

Controlled Product

CAS: 56-47-3

Deoxy corticosterone acetate is a synthetic analogue of the natural compound corticosterone. It has been shown to cause liver lesions, cardiac effects, and hypertension in laboratory animals. Deoxy corticosterone acetate binds to dinucleotide phosphate and prevents its conversion into cytosolic calcium. This interaction inhibits the phosphorylation of myocardial proteins and reduces the production of ATP in heart muscle cells. The binding of deoxycorticosterone acetate to DNA is also an important factor in its toxicity.

Formula: C₂₃H₃₂O₄

Purity: Min. 97 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 372.5 g/mol

Ref: 3D-FD21044

Deoxy Corticosterone Acetate

Controlled Product

CAS: 56-47-3

Applications Adrenocortical/mineralocorticoid Steroid.
References Quigley, J., et al.: Clin. Exper. Pharmacol. Physiol., 36, 724 (2009),

Formula: C₂₃H₃₂O₄

Color and Shape: Off-White

Molecular weight: 372.50

Ref: TR-D232595