CAS 56001-37-7

Guanosine 5′-(tetrahydrogen triphosphate), sodium salt (1:2)

Description:

Guanosine 5′-(tetrahydrogen triphosphate), sodium salt (1:2), commonly referred to as GTP, is a nucleotide that plays a crucial role in cellular metabolism and signaling. It consists of a guanine base, a ribose sugar, and a triphosphate group. The sodium salt form indicates that sodium ions are associated with the triphosphate moiety, which can influence its solubility and stability in aqueous solutions. GTP is essential for protein synthesis, serving as a substrate for RNA polymerases during transcription and as a source of energy in various biochemical reactions. It also acts as a signaling molecule in cellular processes, particularly in the activation of G-proteins. The compound is typically found in a crystalline form and is soluble in water, making it readily available for biological functions. Its structure allows for the transfer of phosphate groups, which is vital in energy transfer and signal transduction pathways. Overall, GTP is integral to numerous physiological processes, highlighting its importance in biochemistry and molecular biology.

Formula: C₁₀H₁₆N₅O₁₄P₃·2Na

InChI: InChI=1S/C10H16N5O14P3.2Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;/t3-,5-,6-,9-;;/m1../s1

InChI key: InChIKey=DHIFWVZWUDFHNP-LGVAUZIVSA-N

SMILES: O[C@H]1[C@H](N2C3=C(N=C2)C(=O)N=C(N)N3)O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]1O.[Na]

Synonyms:

• 2-amino-9-[5-O-(hydroxy{[hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl)-beta-D-glycero-pentofuranosyl]-3,9-dihydro-6H-purin-6-one
• 5'-O-({[(phosphonatooxy)phosphinato]oxy}phosphinato)guanosine
• 5′-GTP di-Na salt
• Disodium 5′-GTP
• Disodium guanosine triphosphate
• GTP disodium salt
• Gtp, Na2H2
• Guanosine 5′-(tetrahydrogen triphosphate), disodium salt
• Guanosine 5′-(tetrahydrogen triphosphate), sodium salt (1:2)
• Guanosine-5'-Triphosphoric Acid Disodium Salt
• Guanosine-5'-Triphosphoric Aicd Disodium Salt
• Guanosine-5'-triphosphate disodium salt

Guanosine-5'-triphosphate disodium salt

CAS: 56001-37-7

Guanosine 5?-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF). Guanosine 5?-Triphosphate, Disodium Salt is a

Formula: C₁₀H₁₄N₅Na₂O₁₄P₃

Color and Shape: White to off-white, Powder

Molecular weight: 567.14

Ref: 02-J61414

Guanosine 5'-(tetrahydrogen triphosphate), disodium salt

CAS: 56001-37-7

Formula: C₁₀H₁₄N₅Na₂O₁₄P₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 567.1441

Ref: IN-DA00I9ZX

Guanosine-5'-triphosphate disodium salt

CAS: 56001-37-7

Guanosine-5'-triphosphate disodium salt

Formula: C₁₀H₁₄N₅O₁₄P₃·2Na

Purity: ≥ 90%

Color and Shape: white powder

Molecular weight: 567.14408g/mol

Ref: 54-BIG4005

Guanosine-5'-triphosphate disodium salt

CAS: 56001-37-7

Guanosine-5'-triphosphate disodium salt

Purity: ≥95%

Molecular weight: 567.14g/mol

Ref: 54-BUP18545

Guanosine-5''-triphosphate disodium salt

CAS: 56001-37-7

Formula: C₁₀H₁₄N₅Na₂O₁₄P₃

Purity: ≥ 85.0%

Color and Shape: White to off-white powder

Molecular weight: 567.15

Ref: 7W-GE2026

Guanosine 5'-triphosphate disodium salt

CAS: 56001-37-7

Guanosine 5'-triphosphate disodium salt is a nucleotide that is involved in energy metabolism and intracellular Ca2+ levels. It also has been shown to be an important regulator of guanine nucleotide-binding, enzyme activities, and receptor activity. This compound is a substrate for the polymerase chain reaction, which can be used to amplify DNA sequences. Guanosine 5'-triphosphate disodium salt has been shown to inhibit the growth of bacterial cells by binding to the antibiotic thiostrepton. The inhibition of bacterial growth is due to the prevention of antibiotic binding to bacterial ribosomes.

Formula: C₁₀H₁₄N₅O₁₄P₃Na₂

Purity: Min. 85 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 567.14 g/mol

Ref: 3D-NG01208

Guanosine-5′-triphosphate (disodium salt)

CAS: 56001-37-7

Purity: 98%

Molecular weight: 567.144

Ref: 10-F987756

Guanosine-5-Triphosphate Disodium Salt (5-GTP-Na2) extrapure, 90%

CAS: 56001-37-7

Formula: C₁₀H₁₄N₅O₁₄P₃Na₂

Purity: min. 90%

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 567.15

Ref: SR-70564

Guanosine-5-triphosphoric aicd disodium salt

CAS: 56001-37-7

Formula: C₁₀H₁₄N₅Na₂O₁₄P₃

Purity: 89.0%

Color and Shape: Solid

Molecular weight: 567.144

Ref: 10-F544631

Guanosine-5'-triphosphate disodium salt

CAS: 56001-37-7

5'-GTP disodium salt boosts myogenic differentiation and fuels cellular processes.

Formula: C₁₀H₁₄N₅Na₂O₁₄P₃

Purity: 95.69% - 99.96%

Color and Shape: Odorless White Solid

Molecular weight: 567.14

Ref: TM-T11511

Guanosine-5'-triphosphate Disodium Salt (~85%)

Controlled Product

CAS: 56001-37-7

Applications Guanosine-5'-triphosphate disodium salt (CAS# 56001-37-7) is a nucleotide used in the preparation of photoreactive GTP affinity probes, and in inhibitors of eukaryotic initiation factor eIF-4E.
References George Cisar, E. A.; J. Am. Chem. Soc., 135, 4676 (2013); Ghosh, P.; et al.: Bioorg. Med. Chem. Lett., 16, 750 (2006).

Formula: C₁₀H₁₄N₅O₁₄P₃Na₂

Purity: ~85%

Color and Shape: Neat

Molecular weight: 567.14

Ref: TR-G838608