CAS 56092-81-0: Ionomycin

Description:Ionomycin is a calcium ionophore, a type of chemical compound that facilitates the transport of calcium ions across cellular membranes. It is derived from the bacterium *Streptomyces conglobatus* and is known for its ability to increase intracellular calcium levels, which can influence various cellular processes, including signal transduction and muscle contraction. Ionomycin is a lipophilic compound, allowing it to easily penetrate lipid membranes. It exhibits a high affinity for calcium ions, making it useful in research settings to study calcium signaling pathways. Additionally, Ionomycin has been employed in various biological assays and experiments, particularly in immunology and cell biology, to activate T-cells and other immune responses. Its mechanism of action involves the formation of complexes with calcium ions, which then diffuse across membranes, leading to an increase in cytosolic calcium concentration. While it has valuable applications in research, caution is advised due to its potent effects on cellular calcium homeostasis, which can lead to cytotoxicity at high concentrations.

Formula:C₄₁H₇₂O₉

InChI:InChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42/h11,13,24-33,36-37,39,42-43,45,48H,12,14-23H2,1-10H3,(H,46,47)/b13-11+,34-24-/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+/m1/s1

InChI key:InChIKey=PGHMRUGBZOYCAA-ADZNBVRBSA-N

SMILES:O=C(O)CCC(C)CC(C)CC(C(=O)C=C(O)C(C)CC(C)CC=CC(C)C(O)C(C)C(O)CC1OC(C)(CC1)C2OC(C)(CC2)C(O)C)C

Synonyms:
(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2′R,5S,5′S)-octahydro-5′-[(1R)-1-hydroxyethyl]-2,5′-dimethyl[2,2′-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid
(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-22-[(2S,5S)-5-[(2R,5S)-5-[(1R)-1-hydroxyethyl]-5-methyl-tetrahydrofuran-2-yl]-5-methyl-tetrahydrofuran-2-yl]-4,6,8,12,14,18,20-heptamethyl-9-oxo-docosa-10,16-dienoic acid
10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2′R,5S,5′S)-octahydro-5′-[(1R)-1-hydroxyethyl]-2,5′-dimethyl[2,2′-bifuran]-5-yl]-9-oxo-, (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-
10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[octahydro-5′-(1-hydroxyethyl)-2,5′-dimethyl[2,2′-bifuran]-5-yl]-9-oxo-, [2S-[2α[2′S*,5′R*(S*)],5β(4S*,6R*,8R*,10Z,12S*,14S*,16E,18S*,19S*,20R*,21R*)]]-
Ionomycin
Ionomycin free acid
Ionomycin calcium salt Streptomyces conglobatus
Ionomycin, Free Acid, Streptomyces conglobatus
Sq 23377
[2S-[2α[2′S*,5′R*(S*)],5β(4S*,6R*,8R*,10Z,12S*,14S*,16E,18S*,19S*,20R*,21R*)]]-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[octahydro-5′-(1-hydroxyethyl)-2,5′-dimethyl[2,2′-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid
See more synonyms

Found 6 products.

Product data	Purity	Price range	Estimated delivery
Ionomycin REF: 7W-GA7872CAS: 56092-81-0	≥ 97.0%	145.00 €~486.00 €	Mon 21 Apr 25
Ionomycin free acid REF: 54-BII0421CAS: 56092-81-0	By hplc: 98.13% (Typical Value in Batch COA)	233.00 €~5,459.00 €	Mon 21 Apr 25
Ionomycin REF: TM-T7285CAS: 56092-81-0	99.54%	187.00 €	Tue 22 Apr 25
Ionomycin Free Acid (85%) REF: TR-I731243CAS: 56092-81-0	85%	318.00 €~2,037.00 €	Wed 28 May 25
Ionomycin REF: 3D-FL162671CAS: 56092-81-0	Min. 98 Area-%	275.00 €~944.00 €	Thu 29 May 25
Ionomycin, Free Acid, Streptomyces conglobatus REF: 10-M01898CAS: 56092-81-0	>98%	- - -	Discontinued product