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CAS 56092-81-0

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Ionomycin

Description:
Ionomycin is a calcium ionophore, a type of chemical compound that facilitates the transport of calcium ions across cellular membranes. It is derived from the bacterium *Streptomyces conglobatus* and is known for its ability to increase intracellular calcium levels, which can influence various cellular processes, including signal transduction and muscle contraction. Ionomycin is a lipophilic compound, allowing it to easily penetrate lipid membranes. It exhibits a high affinity for calcium ions, making it useful in research settings to study calcium signaling pathways. Additionally, Ionomycin has been employed in various biological assays and experiments, particularly in immunology and cell biology, to activate T-cells and other immune responses. Its mechanism of action involves the formation of complexes with calcium ions, which then diffuse across membranes, leading to an increase in cytosolic calcium concentration. While it has valuable applications in research, caution is advised due to its potent effects on cellular calcium homeostasis, which can lead to cytotoxicity at high concentrations.
Formula:C41H72O9
InChI:InChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42/h11,13,24-33,36-37,39,42-43,45,48H,12,14-23H2,1-10H3,(H,46,47)/b13-11+,34-24-/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+/m1/s1
InChI key:InChIKey=PGHMRUGBZOYCAA-ADZNBVRBSA-N
SMILES:C[C@@]1(O[C@H](C[C@@H]([C@@H]([C@@H]([C@@H](/C=C/C[C@H](C[C@H](/C(=C/C([C@H](C[C@H](C[C@@H](CCC(O)=O)C)C)C)=O)/O)C)C)C)O)C)O)CC1)[C@@]2(O[C@@]([C@@H](C)O)(C)CC2)[H]
Synonyms:
  • (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2′R,5S,5′S)-octahydro-5′-[(1R)-1-hydroxyethyl]-2,5′-dimethyl[2,2′-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid
  • (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-22-[(2S,5S)-5-[(2R,5S)-5-[(1R)-1-hydroxyethyl]-5-methyl-tetrahydrofuran-2-yl]-5-methyl-tetrahydrofuran-2-yl]-4,6,8,12,14,18,20-heptamethyl-9-oxo-docosa-10,16-dienoic acid
  • 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2′R,5S,5′S)-octahydro-5′-[(1R)-1-hydroxyethyl]-2,5′-dimethyl[2,2′-bifuran]-5-yl]-9-oxo-, (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-
  • 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[octahydro-5′-(1-hydroxyethyl)-2,5′-dimethyl[2,2′-bifuran]-5-yl]-9-oxo-, [2S-[2α[2′S*,5′R*(S*)],5β(4S*,6R*,8R*,10Z,12S*,14S*,16E,18S*,19S*,20R*,21R*)]]-
  • Ionomycin
  • Ionomycin free acid
  • Ionomycin calcium salt Streptomyces conglobatus
  • Ionomycin, Free Acid, Streptomyces conglobatus
  • Sq 23377
  • [2S-[2α[2′S*,5′R*(S*)],5β(4S*,6R*,8R*,10Z,12S*,14S*,16E,18S*,19S*,20R*,21R*)]]-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[octahydro-5′-(1-hydroxyethyl)-2,5′-dimethyl[2,2′-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid
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Found 5 products.
  • Ionomycin
    Glentham
    + Info

    Ionomycin

    CAS:
    Formula:C41H72O9
    Purity:≥ 97.0%
    Color and Shape:Off-white to yellow oil or wax-like material
    Molecular weight:709.02

    Ref: 7W-GA7872

    1mg
    145.00€
    5mg
    367.00€
    10mg
    486.00€
  • Ionomycin free acid
    Apollo Scientific
    + Info

    Ionomycin free acid

    CAS:
    <p>Ionomycin free acid</p>
    Formula:C41H72O9
    Purity:By hplc: 98.13% (Typical Value in Batch COA)
    Color and Shape: waxy solid
    Molecular weight:709.00498g/mol

    Ref: 54-BII0421

    5mg
    222.00€
    10mg
    379.00€
    25mg
    814.00€
    50mg
    1,327.00€
    100mg
    2,386.00€
    250mg
    5,216.00€
  • Ionomycin
    Targetmol
    + Info

    Ionomycin

    CAS:
    <p>Ionomycin is a calcium ionophore and a Ca2+ -binding antibiotic, increases intracellular Ca 2 + to induce cellular responses. High-Quality, Low-Cost!</p>
    Formula:C41H72O9
    Purity:99.54%
    Color and Shape:Pale Yellow Oil
    Molecular weight:709.01

    Ref: TM-T7285

  • Ionomycin Free Acid (85%)
    TRC
    + Info

    Ionomycin Free Acid (85%)

    Controlled Product
    CAS:
    <p>Stability Light Sensitive<br>Applications Ionomycin free acid is a potent and selective calcium ionophore.<br></p>
    Formula:C41H72O9
    Purity:85%
    Color and Shape:Neat
    Molecular weight:709.005

    Ref: TR-I731243

    1mg
    282.00€
    5mg
    1,153.00€
    10mg
    1,807.00€
  • Ionomycin
    Biosynth
    + Info

    Ionomycin

    CAS:
    <p>Ionomycin is an ionophore compound with a mode of action that facilitates calcium ion transport across cell membranes. It is used in research to study calcium signaling and T-cell activation.</p>
    Formula:C41H72O9
    Purity:Min. 98 Area-%
    Color and Shape:Powder
    Molecular weight:709.01 g/mol

    Ref: 3D-FL162671

    1mg
    252.00€
    2mg
    394.00€
    5mg
    561.00€
    10mg
    864.00€