CAS 561-63-7

19-hydroxycholesterol

Description:

19-Hydroxycholesterol, with the CAS number 561-63-7, is a steroid compound that is a derivative of cholesterol. It is characterized by the presence of a hydroxyl (-OH) group at the 19th carbon position of the steroid nucleus. This modification alters its biochemical properties and biological activity compared to cholesterol. 19-Hydroxycholesterol is typically a white to off-white solid and is soluble in organic solvents, reflecting its lipophilic nature. It plays a role in various biological processes, including cholesterol metabolism and steroidogenesis. The compound is of interest in research related to cardiovascular health and metabolic disorders, as it may influence lipid profiles and cellular signaling pathways. Additionally, its structural similarity to other sterols allows it to interact with various enzymes and receptors in the body. As with many steroid derivatives, it is important to handle 19-hydroxycholesterol with care in laboratory settings, considering its potential biological effects and the need for proper safety protocols.

Formula: C₂₇H₄₆O₂

InChI: InChI=1/C27H46O2/c1-18(2)6-5-7-19(3)23-10-11-24-22-9-8-20-16-21(29)12-15-27(20,17-28)25(22)13-14-26(23,24)4/h8,18-19,21-25,28-29H,5-7,9-17H2,1-4H3/t19-,21+,22+,23-,24+,25+,26-,27-/m1/s1

Synonyms:

• Cholest-5-ene-3,19-diol, (3beta)-
• (3Beta)-Cholest-5-Ene-3,19-Diol

19-Hydroxycholesterol

CAS: 561-63-7

Formula: C₂₇H₄₆O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 402.6529

Ref: IN-DA00DABO

19-hydroxy Cholesterol

CAS: 561-63-7

19-hydroxy Cholesterol is an oxysterol that promotes atherosclerosis.

Formula: C₂₇H₄₆O₂

Color and Shape: Solid

Molecular weight: 402.65

Ref: TM-T36217

19-Hydroxy Cholesterol

CAS: 561-63-7

Formula: C27H46O2

Purity: >98%

Color and Shape: Solid

Molecular weight: 402.65

Ref: 48-64-0060

19-Hydroxy Cholesterol

CAS: 561-63-7

Applications A metabolite of Cholesterol. Cholesterol oxidation product having cytotoxicity effects.
References Higley, N., et al.: Food Chem. Toxicol., 22, 983 (1984), Emanuel, H., et al.: J. Food Sci., 56, 843 (1991), Kilsdonk, E., et al.: J. Lipid Res., 36, 505 (1995), Cantwell, H., et al.: Cell Biol. Toxicol., 14, 401 (1998),

Formula: C₂₇H₄₆O₂

Color and Shape: Neat

Molecular weight: 402.65

Ref: TR-H918005

19-Hydroxy cholesterol

Controlled Product

CAS: 561-63-7

19-Hydroxy cholesterol is a sterol that is one of the primary products of cholesterol synthesis. It is a secondary bile acid and an oxysterol, which are produced in the liver during cholesterol metabolism. 19-Hydoxycholesterol has been shown to induce apoptosis in leukemia cells, as well as inhibit tumor cell growth. This compound can also inhibit the production of fatty acids by inhibiting β-unsaturated ketones, which are intermediates in the biosynthesis of fatty acids. The inhibition of these ketones leads to an increase in the production of n-3 fatty acids, which have been shown to have beneficial effects on human health. 19-Hydroxycholesterol can be detected using a chemical ionization method with gas chromatography and mass spectroscopy detection.

Formula: C₂₇H₄₆O₂

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 402.65 g/mol

Ref: 3D-FH23940

19-Hydroxycholesterol

CAS: 561-63-7

Formula: C₂₇H₄₆O₂

Molecular weight: 402.66

Ref: ST-EA-CP-C71035