CAS 561-78-4

4-Piperidinol, 1,3-dimethyl-4-phenyl-, 4-propanoate, hydrochloride (1:1), (3R,4S)-rel-

Description:

4-Piperidinol, 1,3-dimethyl-4-phenyl-, 4-propanoate, hydrochloride (1:1), (3R,4S)-rel- is a chemical compound characterized by its piperidine ring structure, which is a six-membered ring containing one nitrogen atom. This compound features a dimethyl group and a phenyl group attached to the piperidine, contributing to its lipophilicity and potential biological activity. The presence of the propanoate moiety indicates that it is an ester, which can influence its solubility and reactivity. As a hydrochloride salt, it is typically more stable and soluble in water compared to its free base form. The (3R,4S)-rel- designation indicates specific stereochemistry, which can significantly affect the compound's pharmacological properties and interactions with biological targets. This compound may be of interest in medicinal chemistry and pharmacology due to its structural features, which could be linked to various therapeutic effects. However, detailed studies would be necessary to fully understand its biological activity and potential applications.

Formula: C₁₆H₂₃NO₂·ClH

InChI: InChI=1/C16H23NO2.ClH/c1-4-15(18)19-16(14-8-6-5-7-9-14)10-11-17(3)12-13(16)2;/h5-9,13H,4,10-12H2,1-3H3;1H/t13-,16+;/s2

InChI key: InChIKey=LFLUADVCIBEPQJ-UVQAMBSMNA-N

SMILES: O(C(CC)=O)[C@]1([C@@H](C)CN(C)CC1)C2=CC=CC=C2.Cl

Synonyms:

• (+-)-1,3-Dimethyl-4-phenyl-4-piperidinol propionate (ester) hydrochloride
• (+-)-alpha-1,3-Dimethyl-4-phenyl-4-propionoxypiperidine hydrochloride
• (3S,4R)-1,3-dimethyl-4-phenylpiperidin-4-yl propanoate hydrochloride (1:1)
• (±)-α-1,3-Dimethyl-4-phenyl-4-propionoxypiperidine hydrochloride
• 1,3-Dimethyl-4-phenyl-4-piperidyl propionate hydrochloride
• 4-Piperidinol, 1,3-dimethyl-4-phenyl-, 4-propanoate, hydrochloride (1:1), (3R,4S)-rel-
• 4-Piperidinol, 1,3-dimethyl-4-phenyl-, propanoate (ester), hydrochloride, (3R,4S)-rel-
• 4-Piperidinol, 1,3-dimethyl-4-phenyl-, propanoate (ester), hydrochloride, cis-(+-)-
• 4-Piperidinol, 1,3-dimethyl-4-phenyl-, propionate (ester), hydrochloride, (±)-
• 4-Piperidinol, 1,3-dimethyl-4-phenyl-, propionate, hydrochloride
• Alphaprodine Hydrochloride [USAN]
• Alphaprodine hydrochloride
• Alphaprodine, dl- hydrochloride
• Nisentil
• Nisentil hydrochloride
• Nisintel
• Nu-1196
• Prisilidene
• Prisilidene hydrochloride
• Propionic acid, 1,3-dimethyl-4-phenyl-4-piperidyl ester, hydrochloride, (+-)-
• Unii-Co51Q2Ei5Z
• alpha-Prodine hydrochloride
• dl-1,3-Dimethyl-4-phenyl-4-piperidinol propionate hydrochloride
• dl-Alphaprodine hydrochloride

Alphaprodine Hydrochloride

Controlled Product

CAS: 561-78-4

Stability Hygroscopic
Applications Analgesic (narcotic). Controlled substance (opiates).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gruber, G.M., et al.: J. Pharmacol. Exp. Ther., 99, 312 (1950), Abdel-Monem, M.M., et al.: J. Med. Chem., 15, 494 (1972),

Formula: C₁₆H₂₃NO₂·ClH

Color and Shape: Off-White

Molecular weight: 297.82

Ref: TR-P755300

Alphaprodine Hydrochloride (1 mg/mL in Methanol)

Controlled Product

CAS: 561-78-4

Formula: C₁₆H₂₃NO₂·ClH

Color and Shape: Single Solution

Molecular weight: 297.82

Ref: TR-KIT8965

a-Prodine hydrochloride

Controlled Product

CAS: 561-78-4

a-Prodine hydrochloride (AP) is an opioid analgesic. It is a synthetic drug that belongs to the piperidine class of drugs. AP has been shown to have a rapid onset of action and is used in the treatment of moderate to severe pain, as well as in sedation prior to surgery. AP is also used for the management of postoperative pain following oral or maxillofacial surgery, and for the relief of pain in patients with cancer. AP may be given intravenously, intramuscularly, or orally. Oral administration should be avoided in patients with depression or those who are receiving monoamine oxidase inhibitors (MAOIs). The salt form of this drug is hydrochloride, which is soluble in water.

Formula: C₁₆H₂₄ClNO₂

Purity: Min. 95%

Molecular weight: 297.82 g/mol

Ref: 3D-FP27171