CAS 5610-40-2: (-)-Securinine

Description: (-)-Securinine is a naturally occurring alkaloid derived from the plant Securinega suffruticosa, which belongs to the family Euphorbiaceae. It is characterized by its complex bicyclic structure, featuring a pyridine and a piperidine ring. This compound exhibits a range of biological activities, including neuroprotective effects, and has been studied for its potential therapeutic applications in neurological disorders. (-)-Securinine is known to interact with various neurotransmitter systems, particularly influencing GABAergic and glutamatergic pathways, which may contribute to its effects on the central nervous system. The substance is typically found in a crystalline form and is soluble in organic solvents. Its stereochemistry is significant, as the (-) enantiomer is the biologically active form. Due to its pharmacological properties, (-)-Securinine has garnered interest in medicinal chemistry and pharmacology, although further research is needed to fully elucidate its mechanisms of action and potential clinical applications.

Formula: C₁₃H₁₅NO₂

InChI: InChI=1S/C13H15NO2/c15-12-7-9-4-5-10-8-13(9,16-12)11-3-1-2-6-14(10)11/h4-5,7,10-11H,1-3,6,8H2/t10-,11-,13+/m1/s1

InChI key: InChIKey=SWZMSZQQJRKFBP-WZRBSPASSA-N

SMILES: O=C1OC23C(C=CC(N4CCCCC42)C3)=C1

Synonyms:

• (11aR,11bS)-9,10,11,11a-tetrahydro-8H-6,11b-methanofuro[2,3-c]pyrido[1,2-a]azepin-2(6H)-one
• (6R,11aS,11bR)-9,10,11,11a-tetrahydro-8H-6,11b-methanofuro[2,3-c]pyrido[1,2-a]azepin-2(6H)-one
• (6S,11aR)-9,10,11,11a-tetrahydro-8H-6,11b-methanofuro[2,3-c]pyrido[1,2-a]azepin-2(6H)-one
• (6S,11aR,11bS)-9,10,11,11a-tetrahydro-8H-6,11b-methanofuro[2,3-c]pyrido[1,2-a]azepin-2(6H)-one
• 6,10-Methanopyrido[1,2-a]azepine-Δ⁹⁽⁶^H^),α-acetic acid, 1,2,3,4,10,10a-hexahydro-10-hydroxy-, γ-lactone
• 8H-6,11b-Methanofuro[2,3-c]pyrido[1,2-a]azepin-2(6H)-one, 9,10,11,11a-tetrahydro-, (6S,11aR,11bS)-
• 9,10,11,11a-tetrahydro-8H-6,11b-methanofuro[2,3-c]pyrido[1,2-a]azepin-2(6H)-one
• NSC 107413
• Securinan-11-one
• Securinin
• l-Securinine
• 6,10-Methanopyrido[1,2-a]azepine-Δ9(6H),α-acetic acid, 1,2,3,4,10,10a-hexahydro-10-hydroxy-, γ-lactone
• Securinine, (-)-
• Securinine

SECURININE

CAS: 5610-40-2

• Formula: C₁₃H₁₅NO₂
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 217.2637

(6S,11Ar,11Bs)-9,10,11,11A-Tetrahydro-8H-6,11B-Methanofuro[2,3-C]Pyrido[1,2-A]Azepin-2(6H)-One

CAS: 5610-40-2

• Purity: 95%
• Molecular weight: 217.26g/mol

(-)-Securinine

CAS: 5610-40-2

• Purity: 99.87%
• Molecular weight: 217.26g/mol

Securinine

CAS: 5610-40-2

• Formula: C₁₃H₁₅NO₂
• Molecular weight: 217.26

Securinine

CAS: 5610-40-2

Securinine, a GABAA receptor antagonist, enhances macrophage clearance of phase II C. burnetii: comparison with …

• Formula: C₁₃H₁₅NO₂
• Purity: 95%~99%
• Molecular weight: 217.268

Securinine

CAS: 5610-40-2

• Formula: C₁₃H₁₅NO₂
• Molecular weight: 217.27

(-)-Securinine

CAS: 5610-40-2

(-)-Securinine (Securinine) is plant-derived alkaloid and also a GABAA receptor antagonist.

• Formula: C₁₃H₁₅NO₂
• Purity: 99.58% - 99.87%
• Color and Shape: Solid
• Molecular weight: 217.26

Securinine

CAS: 5610-40-2

Natural alkaloid

• Formula: C₁₃H₁₅NO₂
• Purity: ≥ 90.0 % (HPLC)
• Molecular weight: 217.26

Securinine

CAS: 5610-40-2

Please enquire for more information about Securinine including the price, delivery time and more detailed …

• Formula: C₁₃H₁₅NO₂
• Purity: Min. 95%
• Molecular weight: 217.26 g/mol

Securinine

CAS: 5610-40-2

Applications Extracted from leaves and roots of Securinega suffruticosa Rehder. The most widely studied of …

• Formula: C₁₃H₁₅NO₂
• Color and Shape: Neat
• Molecular weight: 217.26