CAS 56105-81-8

(2R)-2-(3-benzoylphenyl)propanoic acid

Description:

(2R)-2-(3-benzoylphenyl)propanoic acid, commonly known as a non-steroidal anti-inflammatory drug (NSAID), exhibits several notable characteristics. It features a propanoic acid backbone with a chiral center at the second carbon, contributing to its specific stereochemistry. The presence of the benzoylphenyl group enhances its lipophilicity, which can influence its absorption and distribution in biological systems. This compound typically exhibits anti-inflammatory, analgesic, and antipyretic properties, making it useful in the treatment of various inflammatory conditions. Its mechanism of action generally involves the inhibition of cyclooxygenase enzymes, leading to a decrease in prostaglandin synthesis. The compound is usually administered in oral form and may have side effects related to gastrointestinal irritation or cardiovascular risks, common to many NSAIDs. Additionally, its solubility and stability can be affected by pH and temperature, which are important considerations in formulation and storage. Overall, (2R)-2-(3-benzoylphenyl)propanoic acid is a significant compound in pharmacology, particularly in pain management and inflammation control.

Formula: C₁₆H₁₄O₃

InChI: InChI=1/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)/t11-/m1/s1

SMILES: C[C@H](c1cccc(c1)C(=O)c1ccccc1)C(=O)O

Synonyms:

• benzeneacetic acid, 3-benzoyl-alpha-methyl-, (alphaR)-

(R)-Ketoprofen

CAS: 56105-81-8

Formula: C₁₆H₁₄O₃

Color and Shape: White To Off-White Solid

Molecular weight: 254.29

Ref: 4Z-K-0223

(R)-(-)-Ketoprofen

Controlled Product

CAS: 56105-81-8

Applications Anti-inflammatory; analgesic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),

Formula: C₁₆H₁₄O₃

Color and Shape: Neat

Molecular weight: 254.28

Ref: TR-K200806

(R)-(-)-Ketoprofen

CAS: 56105-81-8

COX1/2 inhibitor; nonsteroidal anti-inflammatory drug

Formula: C₁₆H₁₄O₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 254.28 g/mol

Ref: 3D-FK24802

Ketoprofen R-Isomer

CAS: 56105-81-8

Formula: C₁₆H₁₄O₃

Molecular weight: 254.3

Ref: ST-EA-CP-K3022

(R)-Ketoprofen

CAS: 56105-81-8

(R)-Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that exhibits oral activity and analgesic properties. Unlike its counterpart, (R)-Ketoprofen does not significantly enhance the increase of inflammatory cytokines (such as Tumor Necrosis Factor (TNF) and Interleukin-1 (IL-1)) induced by LPS. However, it can inhibit the anti-inflammatory activity of (S)-Ketoprofen.

Formula: C₁₆H₁₄O₃

Color and Shape: Solid

Molecular weight: 254.28

Ref: TM-T200162