CAS 5623-18-7

Metfol-B

Description:

Metfol-B, with the CAS number 5623-18-7, is a chemical compound primarily recognized as a form of folate, specifically a derivative of vitamin B9. It is characterized by its role in biological systems as a coenzyme involved in various metabolic processes, including the synthesis of nucleic acids and amino acids. Metfol-B is particularly important for cellular division and growth, making it essential for processes such as DNA replication and repair. This compound is often utilized in dietary supplements and fortified foods to prevent folate deficiency, which can lead to health issues such as anemia and neural tube defects during pregnancy. In terms of its physical properties, Metfol-B is typically a stable, water-soluble compound, which enhances its bioavailability in the human body. Its safety profile is generally favorable when consumed within recommended dietary allowances, although excessive intake may lead to adverse effects. Overall, Metfol-B plays a crucial role in maintaining overall health and supporting metabolic functions.

Formula: C₁₅H₁₄N₆O₃

InChI: InChI=1S/C15H14N6O3/c1-21(10-4-2-8(3-5-10)14(23)24)7-9-6-17-12-11(18-9)13(22)20-15(16)19-12/h2-6H,7H2,1H3,(H,23,24)(H3,16,17,19,20,22)

InChI key: InChIKey=QHNLFEQJGRZKTK-UHFFFAOYSA-N

SMILES: O=C1C=2C(=NC(N)=N1)NC=C(CN(C)C3=CC=C(C(O)=O)C=C3)N2

Synonyms:

• 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]benzoic acid
• Benzoic Acid, 4-[[(2-Amino-1,4-Dihydro-4-Oxo-6-Pteridinyl)Methyl]Methylamino]-
• Benzoic acid, 4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]-
• Benzoic acid, p-[[(2-amino-4-hydroxy-6-pteridinyl)methyl]methylamino]-
• Metfol-B
• NSC 408937

N10-Methylpteroic Acid

CAS: 5623-18-7

Color and Shape: Neat

Ref: 86-MM0040.04

Methotrexate EP Impurity D

CAS: 5623-18-7

Formula: C₁₅H₁₄N₆O₃

Molecular weight: 326.32

Ref: 4Z-M-705

N10-Methyl Pteroic Acid

CAS: 5623-18-7

Impurity Methotrexate EP Impurity D
Applications N10-Methyl Pteroic Acid (Methotrexate EP Impurity D) is a Methotrexate (M260675) impurity D.
References Cramer, S., et al.: Cancer Res. 1984, 44, 1843 (1984), Hendel, J., et al.: Eur. J. Clin. Pharmacol., 26, 103 (1984),

Formula: C₁₅H₁₄N₆O₃

Color and Shape: Orange To Dark Red

Molecular weight: 326.31

Ref: TR-M326265

N10-Methyl pteroic acid

CAS: 5623-18-7

N10-Methyl pteroic acid is a novel immunosuppressant that inhibits T-cell proliferation and promotes regression of inflammatory bowel disease. It has been shown to be effective in treating cancer patients, with the terminal half-life being approximately 20 hours. N10-Methyl pteroic acid is a potent inhibitor of human acute lymphoblastic leukemia cells. It can also be used as an immunosuppressant for organ transplantation, with desorption from gels using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI TOF MS) and bioanalytical methods such as high performance liquid chromatography (HPLC).

Formula: C₁₅H₁₄N₆O₃

Purity: Min. 95%

Molecular weight: 326.31 g/mol

Ref: 3D-FM25554

Methotrexate EP Impurity D

CAS: 5623-18-7

Formula: C₁₅H₁₄N₆O₃

Molecular weight: 326.3

Ref: ST-EA-CP-M12004