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1,4-Piperazinediethanesulfonic acid

CAS 5625-37-6: 1,4-Piperazinediethanesulfonic acid

Description:1,4-Piperazinediethanesulfonic acid, commonly referred to as PIPES, is a buffering agent widely used in biological and biochemical research. It is a zwitterionic compound, meaning it contains both positive and negative charges, which allows it to maintain a stable pH in solution. PIPES has a pKa value that makes it effective in the physiological pH range, typically around 6.1 to 7.5, making it suitable for various biological applications. The compound is soluble in water, and its stability is generally good under physiological conditions, although it can be sensitive to extreme pH levels and high temperatures. PIPES is often utilized in cell culture, protein purification, and electrophoresis, as it does not interfere with most biochemical reactions. Additionally, it is non-toxic to cells, which is a crucial characteristic for its use in biological systems. Overall, PIPES is valued for its buffering capacity, low absorbance in the UV range, and minimal reactivity with biomolecules, making it a versatile tool in laboratory settings.

Formula:C8H18N2O6S2

InChI:InChI=1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)

InChI key:InChIKey=IHPYMWDTONKSCO-UHFFFAOYSA-N

SMILES:O=S(=O)(O)CCN1CCN(CC1)CCS(=O)(=O)O

  • Synonyms:
  • 1,4-Piperazinebis(ethanesulfonic acid)
  • 1,4-Piperazinediethanesulfonic Acid
  • 2,2-(Piperazine-1,4-Diyl)Bis(Ethanesulphonic) Acid
  • 2,2′-Piperazine-1,4-diyl-bis-ethanesulfonic acid
  • 2-[4-(2-Sulfoethyl)piperazin-1-yl]ethanesulfonic acid
  • Labotest-Bb Lt00138111
  • NSC 157117
  • PIPES Piperazine-N,N-bis(2-ethanesulfonic acid)
  • PIPES, Free Acid, MB Grade (1.12030)
  • PIPES, Free Acid, ULTROL Grade
  • See more synonyms
  • PIPES, Molecular Biology Grade Piperazine-N,N-bis(2-ethanesulfonic acid), Molecular Biology Grade
  • Piperazine-1,4-bis(2-ethanesulfonic acid)
  • Piperazine-1,4-bisethanesulfonic acid
  • Piperazine-N,N'-bis(2-ethanesulfonic acid)
  • Piperazine-Nn'-Bis-2-Ethanesulphonic Acid
  • Pipes
  • Timtec-Bb Sbb008973
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BrandProduct dataPurityPrice rangeEstimated delivery
Alfa Aesar By Thermo Fisher Scientific logo
PIPES, 1.0M buffer soln., pH 6.8
REF: 02-J60300
CAS: 5625-37-6
- - -133.00 €~214.00 €Mon 28 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
PIPES, 98%
REF: 02-A16090
CAS: 5625-37-6
98%37.00 €~400.00 €Mon 28 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
PIPES, 0.5M buffer soln., pH 8.0
REF: 02-J61406
CAS: 5625-37-6
- - -82.00 €~127.00 €Mon 28 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
PIPES, 0.5M buffer soln., pH 7.5
REF: 02-J63617
CAS: 5625-37-6
- - -84.00 €~128.00 €Mon 28 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
PIPES, 1.0M buffer soln., pH 6.5
REF: 02-J60659
CAS: 5625-37-6
- - -127.00 €~204.00 €Mon 28 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
PIPES, 0.5M buffer soln., pH 6.5
REF: 02-J61224
CAS: 5625-37-6
- - -To inquireMon 28 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
PIPES, 1.0M buffer soln., pH 8.0
REF: 02-J60618
CAS: 5625-37-6
- - -To inquireMon 28 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
PIPES, 1.0M buffer soln., pH 7.0
REF: 02-J62195
CAS: 5625-37-6
- - -141.00 €~227.00 €Mon 28 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
PIPES, 1.0M buffer soln., pH 7.5
REF: 02-J62494
CAS: 5625-37-6
- - -To inquireMon 28 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
PIPES, 0.5M buffer soln., pH 6.8
REF: 02-J61786
CAS: 5625-37-6
- - -86.00 €~134.00 €Mon 28 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
PIPES, 0.5M buffer soln., pH 7.0
REF: 02-J63234
CAS: 5625-37-6
- - -76.00 €~117.00 €Mon 28 Apr 25
Indagoo logo
2,2'-(Piperazine-1,4-diyl)diethanesulfonic acid
REF: IN-DA003DPK
CAS: 5625-37-6
98%25.00 €~130.00 €Fri 02 May 25
Apollo Scientific logo
PIPES
REF: 54-BUP19815
CAS: 5625-37-6
≥98%50.00 €Mon 05 May 25
Glentham logo
PIPES
REF: 7W-GB1808
CAS: 5625-37-6
(Titration) ≥ 99.0% (dried basis)33.00 €~243.00 €Mon 05 May 25
Targetmol logo
PIPES
REF: TM-T40645
CAS: 5625-37-6
99.02%34.00 €Mon 05 May 25
Apollo Scientific logo
Piperazine-N,N'-bis-(2-ethanesulphonic acid) Ultrapure
REF: 54-BIB2004
CAS: 5625-37-6
>99.5%52.00 €~245.00 €Mon 05 May 25
Acros logo
PIPES, 98.5+%, for biochemistry
REF: AC-17261
CAS: 5625-37-6
98.5+%To inquireMon 05 May 25
Fluorochem logo
Piperazine-N,N-bis(2-ethanesulfonic acid)
REF: 10-F045145
CAS: 5625-37-6
99.0%17.00 €~94.00 €Mon 05 May 25
Sisco Research Laboratories logo
PIPES Buffer for tissue culture, 99%
REF: SR-48112
CAS: 5625-37-6
min. 99%27.00 €~59.00 €Fri 30 May 25
Sisco Research Laboratories logo
PIPES Buffer extrapure, 99%
REF: SR-70375
CAS: 5625-37-6
min. 99%27.00 €~149.00 €Fri 30 May 25
discount label

PIPES, 1.0M buffer soln., pH 6.8

CAS:5625-37-6

Ref: 02-J60300

250ml133.00 €
500ml214.00 €
Estimated delivery in United States, on Monday 28 Apr 2025
discount label

PIPES, 98%

CAS:5625-37-6

Ref: 02-A16090

25g37.00 €
100g101.00 €
500g400.00 €
Estimated delivery in United States, on Monday 28 Apr 2025
discount label

PIPES, 0.5M buffer soln., pH 8.0

CAS:5625-37-6

Ref: 02-J61406

100ml82.00 €
250ml127.00 €
Estimated delivery in United States, on Monday 28 Apr 2025
discount label

PIPES, 0.5M buffer soln., pH 7.5

CAS:5625-37-6

Ref: 02-J63617

100ml84.00 €
250ml128.00 €
Estimated delivery in United States, on Monday 28 Apr 2025
discount label

PIPES, 1.0M buffer soln., pH 6.5

CAS:5625-37-6

Ref: 02-J60659

250ml127.00 €
500ml204.00 €
Estimated delivery in United States, on Monday 28 Apr 2025
discount label

PIPES, 0.5M buffer soln., pH 6.5

CAS:5625-37-6

Ref: 02-J61224

100mlTo inquire
250mlTo inquire
Estimated delivery in United States, on Monday 28 Apr 2025
discount label

PIPES, 1.0M buffer soln., pH 8.0

CAS:5625-37-6

Ref: 02-J60618

250ml145.00 €
500mlTo inquire
Estimated delivery in United States, on Monday 28 Apr 2025
discount label

PIPES, 1.0M buffer soln., pH 7.0

CAS:5625-37-6

Ref: 02-J62195

250ml141.00 €
500ml227.00 €
Estimated delivery in United States, on Monday 28 Apr 2025
discount label

PIPES, 1.0M buffer soln., pH 7.5

CAS:5625-37-6

Ref: 02-J62494

250ml128.00 €
500mlTo inquire
Estimated delivery in United States, on Monday 28 Apr 2025
discount label

PIPES, 0.5M buffer soln., pH 6.8

CAS:5625-37-6

Ref: 02-J61786

100ml86.00 €
250ml134.00 €
Estimated delivery in United States, on Monday 28 Apr 2025
discount label

PIPES, 0.5M buffer soln., pH 7.0

CAS:5625-37-6

Ref: 02-J63234

100ml76.00 €
250ml117.00 €
Estimated delivery in United States, on Monday 28 Apr 2025
discount label

2,2'-(Piperazine-1,4-diyl)diethanesulfonic acid

CAS:5625-37-6

Ref: IN-DA003DPK

25g25.00 €
100g33.00 €
500g77.00 €
Estimated delivery in United States, on Friday 2 May 2025
discount label

PIPES

CAS:5625-37-6

Ref: 54-BUP19815

5g50.00 €
Estimated delivery in United States, on Monday 5 May 2025
discount label

PIPES

CAS:5625-37-6

Ref: 7W-GB1808

25g33.00 €
100g74.00 €
250g148.00 €
500g243.00 €
Estimated delivery in United States, on Monday 5 May 2025
discount label

PIPES

CAS:5625-37-6

Ref: TM-T40645

5g34.00 €
Estimated delivery in United States, on Monday 5 May 2025
discount label

Piperazine-N,N'-bis-(2-ethanesulphonic acid) Ultrapure

CAS:5625-37-6

Ref: 54-BIB2004

1kg245.00 €
100g52.00 €
250g104.00 €
Estimated delivery in United States, on Monday 5 May 2025
discount label

PIPES, 98.5+%, for biochemistry

CAS:5625-37-6

Ref: AC-17261

25g42.00 €
100g111.00 €
500g371.00 €
2500gTo inquire
Estimated delivery in United States, on Monday 5 May 2025
discount label

Piperazine-N,N-bis(2-ethanesulfonic acid)

CAS:5625-37-6

Ref: 10-F045145

1kg94.00 €
25g17.00 €
100g17.00 €
500g49.00 €
Estimated delivery in United States, on Monday 5 May 2025
discount label

PIPES Buffer for tissue culture, 99%

CAS:5625-37-6

Ref: SR-48112

25g27.00 €
100g59.00 €
Estimated delivery in United States, on Friday 30 May 2025
discount label

PIPES Buffer extrapure, 99%

CAS:5625-37-6

Ref: SR-70375

25g27.00 €
100g48.00 €
500g149.00 €
Estimated delivery in United States, on Friday 30 May 2025
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