CAS 5625-37-6

1,4-Piperazinediethanesulfonic acid

Description:

1,4-Piperazinediethanesulfonic acid, commonly referred to as PIPES, is a buffering agent widely used in biological and biochemical research. It is a zwitterionic compound, meaning it contains both positive and negative charges, which allows it to maintain a stable pH in solution. PIPES has a pKa value that makes it effective in the physiological pH range, typically around 6.1 to 7.5, making it suitable for various biological applications. The compound is soluble in water, and its stability is generally good under physiological conditions, although it can be sensitive to extreme pH levels and high temperatures. PIPES is often utilized in cell culture, protein purification, and electrophoresis, as it does not interfere with most biochemical reactions. Additionally, it is non-toxic to cells, which is a crucial characteristic for its use in biological systems. Overall, PIPES is valued for its buffering capacity, low absorbance in the UV range, and minimal reactivity with biomolecules, making it a versatile tool in laboratory settings.

Formula: C₈H₁₈N₂O₆S₂

InChI: InChI=1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)

InChI key: InChIKey=IHPYMWDTONKSCO-UHFFFAOYSA-N

SMILES: C(CS(=O)(=O)O)N1CCN(CCS(=O)(=O)O)CC1

Synonyms:

• 1,4-Piperazinebis(ethanesulfonic acid)
• 1,4-Piperazinediethanesulfonic Acid
• 2,2-(Piperazine-1,4-Diyl)Bis(Ethanesulphonic) Acid
• 2,2′-Piperazine-1,4-diyl-bis-ethanesulfonic acid
• 2-[4-(2-Sulfoethyl)piperazin-1-yl]ethanesulfonic acid
• Labotest-Bb Lt00138111
• NSC 157117
• PIPES Piperazine-N,N-bis(2-ethanesulfonic acid)
• PIPES, Free Acid, MB Grade (1.12030)
• PIPES, Free Acid, ULTROL Grade
• PIPES, Molecular Biology Grade Piperazine-N,N-bis(2-ethanesulfonic acid), Molecular Biology Grade
• Piperazine-1,4-bis(2-ethanesulfonic acid)
• Piperazine-1,4-bisethanesulfonic acid
• Piperazine-N,N'-bis(2-ethanesulfonic acid)
• Piperazine-Nn'-Bis-2-Ethanesulphonic Acid
• Pipes

PIPES Buffer PrimeDx, 99%

CAS: 5625-37-6

Formula: C₈H₁₈N₂O₆S₂

Purity: min. 99.0%

Color and Shape: White, Powder, Clear, Colourless

Molecular weight: 302.36

Ref: SR-86180

PIPES

CAS: 5625-37-6

PIPES, also known as, Piperazine-N,N-bis(2-ethanesulfonic acid) is a piperazinic buffer with an optimal pH range of 6.1-7.5 and a pKa of 6.76. This buffering agent can be used in culture media, crystallization, electrophoresis, and chromatography and is non-coordinating.

Formula: C₈H₁₈N₂O₆S₂

Color and Shape: White Off-White Powder

Molecular weight: 302.37 g/mol

Ref: 3D-FP11594