CAS 56253-90-8

L-Phenyl-d5-alanine

Description:

L-Phenyl-d5-alanine, with the CAS number 56253-90-8, is a deuterated form of the amino acid L-phenylalanine, where five hydrogen atoms are replaced by deuterium, a stable isotope of hydrogen. This modification enhances its utility in various scientific applications, particularly in NMR spectroscopy, where deuteration improves spectral resolution and reduces background noise. L-Phenyl-d5-alanine retains the fundamental characteristics of L-phenylalanine, including its role as a building block for proteins and its involvement in metabolic pathways. It is an essential amino acid, meaning it must be obtained through diet, and is known for its role in synthesizing neurotransmitters such as dopamine. The presence of deuterium can also influence the compound's physical and chemical properties, such as solubility and stability. L-Phenyl-d5-alanine is typically used in research settings, particularly in studies involving protein structure and dynamics, as well as in metabolic labeling experiments. Its unique isotopic composition makes it a valuable tool in biochemical and pharmaceutical research.

Formula: C₉H₆D₅NO₂

InChI: InChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1/i1D,2D,3D,4D,5D

InChI key: InChIKey=COLNVLDHVKWLRT-HRVDQBBZSA-N

SMILES: C([C@@H](C(O)=O)N)C1=C(C(=C(C(=C1[2H])[2H])[2H])[2H])[2H]

Synonyms:

• L-Phenylalanine-2,3,4,5,6-d5
• L-Phenylalanine-d5
• L-Phenyl-d5-alanine
• [2H5]Phenylalanine
• L-(2,3,4,5,6-2H5)Phenylalanine

L-Phenylalanine-D5

CAS: 56253-90-8

L-Phenylalanine-D5

Purity: 98%

Molecular weight: 170.22g/mol

Ref: 54-DE2115

L-Phenyl-d5-alanine

CAS: 56253-90-8

Formula: C₆D₅CH₂CH(NH₂)COOH

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 170.11036

Ref: 3U-D1589

L-Phenylalanine-d5

CAS: 56253-90-8

Formula: C₉H₆D₅NO₂

Molecular weight: 170.22

Ref: 4Z-P-217031

L-Phenylalanine-d5

Controlled Product

CAS: 56253-90-8

Applications Labeled L-Phenylalanine is an essential amino acid. L-Phenylalanine is biologically converted into L-tyrosine, another one of the DNA-encoded amino acids, which in turn is converted to L-DOPA and further converted into dopamine, norepinephrine, and epinephrine. L-Phenylalanine is produced for medical, feed, and nutritional applications such as in the preparation of Aspartame.
References Hollunger, G. et al.: Acta Pharmacol. Toxicol., 34, 391 (1974); Bagchi, S.P. et al.: Biochem. Pharmacol., 26, 900 (1977);

Formula: C₉₂H₅H₆NO₂

Color and Shape: White To Off-White

Molecular weight: 170.22

Ref: TR-P319418

L-Phenylalanine-d5

CAS: 56253-90-8

L-Phenylalanine-d5 is a stable isotope of phenylalanine that can be used to study the metabolic effects of this amino acid. L-Phenylalanine-d5 has been shown to increase fatty acid oxidation and mitochondrial biogenesis in Sprague-Dawley rats, which may be due to its ability to activate the receptor α. L-Phenylalanine-d5 also has an effect on insulin resistance, as it increases the expression of hydroxylase in liver tissue. The analytical methods for determining concentrations of L-phenylalanine-d5 are based on NMR spectra or fatty acids content.

Formula: C₉H₁₁NO₂

Purity: Min. 95%

Molecular weight: 170.22 g/mol

Ref: 3D-GCA25390

L-PHENYL-D5-ALANINE

CAS: 56253-90-8

Formula: C₉H₆D₅NO₂

Purity: %

Color and Shape: Solid

Molecular weight: 170.2199

Ref: IN-DA00DALW