CAS 5626-34-6

Prednisolone 21-diethylaminoacetate

Description:

Prednisolone 21-diethylaminoacetate is a synthetic corticosteroid derivative of prednisolone, primarily used for its anti-inflammatory and immunosuppressive properties. It is characterized by its ability to modulate various physiological processes, including the immune response and inflammation. The compound features a steroid backbone typical of corticosteroids, which contributes to its biological activity. Prednisolone 21-diethylaminoacetate is often administered in clinical settings to treat conditions such as allergies, autoimmune disorders, and certain types of cancer. Its pharmacological effects are mediated through the binding to glucocorticoid receptors, leading to alterations in gene expression. The substance is typically formulated for parenteral administration, allowing for rapid onset of action. As with other corticosteroids, potential side effects may include weight gain, increased susceptibility to infections, and alterations in glucose metabolism. Proper dosage and monitoring are essential to minimize adverse effects while maximizing therapeutic benefits. Overall, this compound exemplifies the utility of synthetic modifications in enhancing the efficacy and specificity of corticosteroid therapies.

Formula: C₂₇H₃₉NO₆

InChI: InChI=1/C27H39NO6/c1-5-28(6-2)15-23(32)34-16-22(31)27(33)12-10-20-19-8-7-17-13-18(29)9-11-25(17,3)24(19)21(30)14-26(20,27)4/h9,11,13,19-21,24,30,33H,5-8,10,12,14-16H2,1-4H3

InChI key: InChIKey=ILZSJEITWDWIRX-FOMYWIRZSA-N

SMILES: C[C@@]12[C@]([C@]3([C@]([C@@H](O)C1)([C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H])(CC[C@@]2(C(COC(CN(CC)CC)=O)=O)O)[H]

Synonyms:

• 11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl N,N-diethylglycinate
• 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-N,N-diethylglycine ester
• Glycine, N,N-diethyl-, (11β)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl ester
• Glycine, N,N-diethyl-, 21-ester with 11β,17,21-trihydroxypregna-1,4-diene-3,20-dione
• Prednisolone 21-Diethylaminoacetate
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-, 21-ester with N,N-diethylglycine
• Prednisolamate
• ILZSJEITWDWIRX-FOMYWIRZSA-N
• N,N-Diethylglycine 11β,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl ester

Prednisolamate-D10

Controlled Product

CAS: 5626-34-6

Applications Prednisolamate-D10 is a labelled analogue of Prednisolamate (P703715).

Formula: C₂₇D₁₀H₂₉NO₆

Color and Shape: Neat

Molecular weight: 483.663

Ref: TR-P703717