CAS 5626-99-3

5,6-dihydrodeoxyuridine

Description:

5,6-Dihydrodeoxyuridine, with the CAS number 5626-99-3, is a nucleoside analog that is structurally related to deoxyuridine. It features a pyrimidine base, specifically uracil, which is modified by the reduction of the double bond between the 5 and 6 positions of the ring, resulting in a saturated structure. This modification can influence its biological activity, particularly in the context of DNA synthesis and repair. The compound is of interest in medicinal chemistry and virology, as it may exhibit antiviral properties and can serve as a substrate for DNA polymerases. Its solubility and stability in biological systems can vary, affecting its pharmacokinetics and potential therapeutic applications. Additionally, 5,6-dihydrodeoxyuridine can be utilized in research to study nucleic acid metabolism and the mechanisms of action of other nucleoside analogs. Overall, its unique structural characteristics make it a valuable compound for further investigation in biochemical and pharmaceutical contexts.

Formula: C₉H₁₄N₂O₅

InChI: InChI=1/C18H13N3O4/c22-18-16(12-19-14-6-2-1-3-7-14)20-17(25-18)10-9-13-5-4-8-15(11-13)21(23)24/h1-12,19H

SMILES: c1ccc(cc1)NC=C1C(=O)OC(=N1)C=Cc1cccc(c1)N(=O)=O

Synonyms:

• 2-[2-(3-nitrophenyl)ethenyl]-4-[(phenylamino)methylidene]-1,3-oxazol-5(4H)-one
• Dihydrodeoxyuridine
• Uridine, 2'-deoxy-5,6-dihydro-
• 5,6-DIHYDRODEOXYURIDINE
• 5,6-DIHYDRO-2'-DEOXYURIDINE
• 2'-Deoxy-5,6-dihydrouridine

2'-Deoxy-5,6-dihydrouridine

CAS: 5626-99-3

2'-Deoxy-5,6-dihydrouridine

Purity: ≥98%

Molecular weight: 230.22g/mol

Ref: 54-BUP20183

5,6-Dihydro-2''-deoxyuridine

CAS: 5626-99-3

Formula: C₉H₁₄N₂O₅

Molecular weight: 230.22

Ref: 7W-GN1663

2'-Deoxy-5,6-dihydrouridine

CAS: 5626-99-3

2'-Deoxy-5,6-dihydrouridine is a nucleoside analog that contains a dihydro group in its molecular structure，commonly used in base excision related studies.

Formula: C₉H₁₄N₂O₅

Purity: 99.75%

Color and Shape: Solid

Molecular weight: 230.22

Ref: TM-TNU1089

5,6-Dihydro-2'-deoxyuridine

CAS: 5626-99-3

5,6-Dihydro-2'-deoxyuridine (dUrd) is a pyrimidine nucleoside that is an important component of DNA. It is phosphorylated by deoxyribonucleoside kinase to form dUrd monophosphate. This compound has been shown to inhibit the activity of catalase and other enzymes that hydrolyze hydrogen peroxide, indicating it may have antiviral properties. The enzyme activities of 5,6-dihydro-2'-deoxyuridine on simplex virus type 1 have been studied in vitro using lymphoblastoid cells. In these studies, the compounds was found to inhibit viral growth and terminate replication. 5,6-Dihydro-2'-deoxyuridine also inhibits the synthesis of DNA by inhibiting oxidative deamination reactions and termini formation in herpes simplex virus type 1. This drug has also been shown to inhibit amine oxidases in hep

Formula: C₉H₁₄N₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 230.22 g/mol

Ref: 3D-ND07999