CAS 5627-00-9

5,6-Dihydrothymidine

Description:

5,6-Dihydrothymidine is a pyrimidine nucleoside derivative, structurally related to thymidine, which is a component of DNA. This compound features a reduced double bond in the pyrimidine ring, specifically at the 5 and 6 positions, which distinguishes it from thymidine. It is characterized by its ability to participate in biochemical processes, particularly in nucleic acid metabolism. The presence of the dihydro group can influence its biological activity and stability compared to its fully unsaturated counterparts. 5,6-Dihydrothymidine is of interest in research related to nucleoside analogs, which can have implications in antiviral and anticancer therapies. Its CAS number, 5627-00-9, is a unique identifier that facilitates the identification and study of this compound in scientific literature and databases. As with many nucleoside derivatives, its solubility, reactivity, and interaction with enzymes can vary, making it a subject of interest in medicinal chemistry and pharmacology.

Formula: C₁₀H₁₆N₂O₅

InChI: InChI=1S/C10H16N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h5-8,13-14H,2-4H2,1H3,(H,11,15,16)/t5?,6-,7+,8+/m0/s1

InChI key: InChIKey=FEYHMSUYKIMUAL-UNYLCCJPSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)CC(C)C(=O)N1

Synonyms:

• 1-[4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3,5,6-tetrahydropyrimidine-2,4-dione
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)dihydro-5-methyl-
• Dihydrothymidine
• Hydrouracil, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-5-methyl-
• Hydrouracil, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-5-methyl-
• Thymidine, 5,6-dihydro-
• 5,6-Dihydrothymidine
• Hydrouracil, 1-(2-deoxy-β-D-ribofuranosyl)-5-methyl-
• Hydrouracil, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-5-methyl-
• 5,6-Dihydro-2'-deoxy-5-methyluridine
• 1-[4-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-5-methyl-1,3-diazinane-2,4-dione
• 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,3-diazinane-2,4-dione
• 5,6-Dihydro thymidine,5,6-Dihydro-2’-deoxy-5-methyl uridine
• (5S)-5,6-Dihydrothymidine
• 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyldihydropyrimidine-2,4(1H,3H)-dione

5,6-Dihydrothymidine

CAS: 5627-00-9

5,6-Dihydrothymidine

Purity: ≥98%

Molecular weight: 244.24g/mol

Ref: 54-BUP21090

5,6-Dihydrothymidine

CAS: 5627-00-9

2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.

Formula: C₁₀H₁₆N₂O₅

Purity: 99.90%

Color and Shape: Solid

Molecular weight: 244.24

Ref: TM-TNU1090

5,6-Dihydrothymidine

CAS: 5627-00-9

5,6-Dihydrothymidine is a hydroxylated thymidine analogue. It binds to the leukocyte antigen, which is found on many different types of cells. 5,6-Dihydrothymidine inhibits the replication of herpes simplex virus and can be used for diagnostic purposes. 5,6-Dihydrothymidine has been shown to have conformational properties that are similar to those of thymine, which allows it to bind to the template strand in DNA. This binding prevents the synthesis of messenger RNA from DNA. 5,6-Dihydrothymidine is also able to inhibit cell growth in culture and can be used as a cell culture medium supplement.

Formula: C₁₀H₁₆N₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 244.24 g/mol

Ref: 3D-ND144870