CAS 5627-05-4

Dihydrouridine

Description:

Dihydrouridine is a modified nucleoside that plays a significant role in RNA structure and function. It is characterized by the presence of a reduced double bond in the uridine base, specifically at the 5,6 position of the pyrimidine ring. This modification can influence the stability and folding of RNA molecules, contributing to their biological activity. Dihydrouridine is commonly found in tRNA, where it helps maintain the proper three-dimensional structure necessary for protein synthesis. The presence of this modification can enhance the thermal stability of tRNA and affect its interaction with ribosomes and aminoacyl-tRNA synthetases. In addition to its structural roles, dihydrouridine may also participate in various biochemical processes, including the regulation of gene expression. Its CAS number, 5627-05-4, is used for identification in chemical databases. Overall, dihydrouridine is an essential component of the RNA world, reflecting the complexity and versatility of nucleic acid modifications in biological systems.

Formula: C₉H₁₄N₂O₆

InChI: InChI=1S/C9H14N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4,6-8,12,14-15H,1-3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1

InChI key: InChIKey=ZPTBLXKRQACLCR-XVFCMESISA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)CC2

Synonyms:

• 1-β-L-ribofuranosyldihydropyrimidine-2,4(1H,3H)-dione
• 2,4(1H,3H)-Pyrimidinedione, dihydro-1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 5,6-Dihydrouridine
• 5627-05-4
• Dihydrouridine
• Hydrouracil, 1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• Uridine, 5,6-dihydro-
• 2,4(1H,3H)-Pyrimidinedione, dihydro-1-β-D-ribofuranosyl-
• Hydrouracil, 1-β-D-ribofuranosyl-

1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one

CAS: 5627-05-4

Formula: C₉H₁₄N₂O₆

Purity: 99%

Color and Shape: Solid

Molecular weight: 246.2173

Ref: IN-DA00DIGY

5,6-Dihydrouridine

CAS: 5627-05-4

5,6-Dihydrouridine

Purity: ≥98%

Molecular weight: 246.22g/mol

Ref: 54-BUP00329

5,6-Dihydrouridine

CAS: 5627-05-4

5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Eukaryota, Bacteria, and some Archaea.

Formula: C₉H₁₄N₂O₆

Purity: 99.57%

Color and Shape: Solid

Molecular weight: 246.22

Ref: TM-T19146

5,6-Dihydrouridine

CAS: 5627-05-4

5,6-Dihydrouridine

Formula: C₉H₁₄N₂O₆

Purity: 95%

Color and Shape: light orange/yellow powder

Molecular weight: 246.22g/mol

Ref: 54-OR17694

5,6-Dihydrouridine

Controlled Product

CAS: 5627-05-4

Formula: C₉H₁₄N₂O₆

Color and Shape: Neat

Molecular weight: 246.22

Ref: TR-D449668

5,6-Dihydrouridine

CAS: 5627-05-4

Purity: 98%

Molecular weight: 246.2189941

Ref: 10-F603086