CAS 5636-83-9

(±)-Dimethindene

Description:

(±)-Dimethindene is an antihistamine belonging to the class of compounds known as diphenylmethanes. It is primarily used for its antiallergic properties, particularly in the treatment of allergic conditions such as hay fever and urticaria. The substance exhibits a strong affinity for histamine H1 receptors, effectively blocking the action of histamine, which is responsible for allergic symptoms. (±)-Dimethindene is characterized by its ability to cross the blood-brain barrier, which can lead to sedative effects, a common side effect of many first-generation antihistamines. The compound is typically administered in the form of its maleate salt, enhancing its solubility and bioavailability. In terms of physical properties, (±)-Dimethindene is a colorless to pale yellow liquid or crystalline solid, with a relatively low molecular weight. Its chemical structure includes a dimethylamino group and a phenyl ring, contributing to its pharmacological activity. As with many medications, it is important to consider potential side effects and contraindications when using (±)-Dimethindene.

Formula: C₂₀H₂₄N₂

InChI: InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3

InChI key: InChIKey=MVMQESMQSYOVGV-UHFFFAOYSA-N

SMILES: C(C)(C=1C=2C(CC1CCN(C)C)=CC=CC2)C3=CC=CC=N3

Synonyms:

• (±)-Dimethindene
• 1H-Indene-2-ethanamine, N,N-dimethyl-3-[1-(2-pyridinyl)ethyl]-
• 2-(1-[2-(2-Dimethylaminoethyl)inden-3-yl]ethyl)pyridine
• 3-[α-(2′-Pyridyl)ethyl]-2-(β-dimethylaminoethyl)indene
• Dimethindene (base and/or unspecified salts)
• Dimethpyrindene
• Dimethyl(2-(3-(1-(2-Pyridyl)Ethyl)Inden-2-Yl)Ethyl)Amine
• Feniallerg
• Forhistal
• N,N-Dimethyl-3-[1-(2-pyridinyl)ethyl]-1H-indene-2-ethanamine
• N,N-dimethyl-2-{3-[1-(pyridin-2-yl)ethyl]-1H-inden-2-yl}ethanamine

Dimethindene

CAS: 5636-83-9

Dimethindene

Purity: ≥98%

Molecular weight: 292.42g/mol

Ref: 54-BUP01042

Dimetindene

CAS: 5636-83-9

Formula: C₂₀H₂₄N₂

Color and Shape: Pale Brown Solid

Molecular weight: 292.43

Ref: 4Z-D-096002

Dimethindene

CAS: 5636-83-9

Dimethindene is a maleate that has been used to treat allergic reactions and other conditions. Dimethindene exhibits anti-inflammatory activity, which may be due to its inhibition of histamine release. The mechanism of action of dimethindene is not fully understood, but it has been hypothesized that the drug inhibits the H1 receptor on mast cells and basophils by competitively blocking the binding of histamine. Dimethindene also blocks the release of prostaglandins from platelets and leukocytes. It is used in experimental models for allergic rhinitis, where it inhibits histamine-induced nasal obstruction and edema.

Formula: C₂₀H₂₄N₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 292.42 g/mol

Ref: 3D-FD66783

Dimethindene

Controlled Product

CAS: 5636-83-9

Applications Dimethindene (cas# 5636-83-9) is a useful research chemical.

Formula: C₂₀H₂₄N₂

Color and Shape: Light Brown

Molecular weight: 292.42

Ref: TR-D460803

Dimethindene

CAS: 5636-83-9

Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.

Formula: C₂₀H₂₄N₂

Purity: 98.3% - 98.99%

Color and Shape: Solid

Molecular weight: 292.42

Ref: TM-T31488