CAS 56377-79-8
:Nosiheptide
Description:
Nosiheptide is a cyclic peptide antibiotic that belongs to the class of thiopeptides, which are known for their unique structural features and potent biological activities. It is produced by certain strains of the bacterium *Nocardia*, and its structure includes a series of amino acids linked by peptide bonds, often featuring unusual amino acids and a thiazole or oxazole ring. Nosiheptide exhibits strong antibacterial properties, particularly against Gram-positive bacteria, making it of interest in the field of medicinal chemistry and antibiotic development. Its mechanism of action typically involves the inhibition of protein synthesis by binding to the ribosomal RNA, disrupting the translation process. Additionally, due to its complex structure, nosiheptide has been studied for its potential applications in treating infections caused by antibiotic-resistant strains. Research into its pharmacological properties, biosynthesis, and potential therapeutic uses continues to be an area of active investigation, highlighting the importance of natural products in drug discovery.
Formula:C51H43N13O12S6
InChI:InChI=1S/C51H43N13O12S6/c1-5-23-46-60-28(14-79-46)41(70)56-25-10-33(67)50(74)76-11-21-7-6-8-24-34(21)18(2)35(54-24)51(75)82-17-31(57-42(71)29-15-80-47(25)61-29)48-58-26(12-78-48)37-22(45-59-30(13-77-45)43(72)64-36(20(4)65)44(73)55-23)9-32(66)38(63-37)49-62-27(16-81-49)40(69)53-19(3)39(52)68/h5-9,12-16,20,25,31,33,36,54,65-67H,3,10-11,17H2,1-2,4H3,(H2,52,68)(H,53,69)(H,55,73)(H,56,70)(H,57,71)(H,64,72)
InChI key:InChIKey=OQAOHXRUMXWDLQ-UHFFFAOYSA-N
SMILES:OC=1C=C2C(C=3N=C(SC3)C4NC(=O)C=5N=C(SC5)C(NC(=O)C=6N=C(C(=CC)NC(=O)C(C(C)O)NC(=O)C=7N=C2SC7)SC6)CC(O)C(=O)OCC8=C9C(C)=C(C(=O)SC4)NC9=CC=C8)=NC1C%10=NC(C(NC(C(N)=O)=C)=O)=CS%10
Synonyms:- Multhiomycin
- 30,32-Imino-8,5:18,15:40,37-trinitrilo-21,36-([2,4]-endo-thiazolomethanimino)-5H,15H,37H-pyrido[3,2-w][2,11,21,27,31,7,14,17]benzoxatetrathiatriazacyclohexatriacontine, nosiheptide deriv.
- Nosiheptide
- N-[1-(Aminocarbonyl)ethenyl]-2-[(11S,14Z,21S,23S,29S)-14-ethylidene-9,10,11,12,13,14,19,20,21,22,23,24,26,33,35,36-hexadecahydro-3,23-dihydroxy-11-[(1R)-1-hydroxyethyl]-31-methyl-9,12,19,24,33,43-hexaoxo-30,32-imino-8,5:18,15:40,37-trinitrilo-21,36-([2,4]-endo-thiazolomethanimino)-5H,15H,37H-pyrido[3,2-w][2,11,21,27,31,7,14,17]benzoxatetrathiatriazacyclohexatriacontin-2-yl]-4-thiazolecarboxamide
- 4-Thiazolecarboxamide, N-[1-(aminocarbonyl)ethenyl]-2-[(11S,14Z,21S,23S,29S)-14-ethylidene-9,10,11,12,13,14,19,20,21,22,23,24,26,33,35,36-hexadecahydro-3,23-dihydroxy-11-[(1R)-1-hydroxyethyl]-31-methyl-9,12,19,24,33,43-hexaoxo-30,32-imino-8,5:18,15:40,37-trinitrilo-21,36-([2,4]-endo-thiazolomethanimino)-5H,15H,37H-pyrido[3,2-w][2,11,21,27,31,7,14,17]benzoxatetrathiatriazacyclohexatriacontin-2-yl]-
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Found 9 products.
4-Thiazolecarboxamide,N-[1-(aminocarbonyl)ethenyl]-2-[(11S,14Z,21S,23S,29S)-14-ethylidene-9,10,11,12,13,14,19,20,21,22,23,24,26,33,35,36-hexadecahydro-3,23-dihydroxy-11-[(1R)-1-hydroxyethyl]-31-methyl-9,12,19,24,33,43-hexaoxo-30,32-imino-8,5:18,15:40,37-trinitrilo-21,36-([2,4]-endo-thiazolomethanimino)-5H,15H,37H-pyrido[3,2-w][2
CAS:Formula:C51H43N13O12S6Purity:96%Color and Shape:SolidMolecular weight:1222.3570Nosiheptide
CAS:Nosiheptide, a thiopeptide antibiotic from Streptomyces actuosus, boosts animal growth; it blocks protein synthesis in bacteria.Formula:C51H43N13O12S6Purity:95.37%Color and Shape:SolidMolecular weight:1222.36N-(3-Amino-3-Oxoprop-1-En-2-Yl)-2-((11S,14Z,21S,23S,29S)-14-Ethylidene-3,23-Dihydroxy-11-((1R)-(1-Hydroxyethyl))-31-Methyl-9,12,19,24,33,43-Hexaoxo-9,10,11,12,13,14,19,20,21,22,23,24,26,33,35,36-Hexad
CAS:N-(3-Amino-3-Oxoprop-1-En-2-Yl)-2-((11S,14Z,21S,23S,29S)-14-Ethylidene-3,23-Dihydroxy-11-((1R)-(1-Hydroxyethyl))-31-Methyl-9,12,19,24,33,43-Hexaoxo-9,10,11,12,13,14,19,20,21,22,23,24,26,33,35,36-HexadPurity:90%Molecular weight:1222.36g/molNosiheptide 100 µg/mL in Acetonitrile:Dimethylsulfoxide
CAS:Formula:C51H43N13O12S6Color and Shape:Single SolutionMolecular weight:1222.36Nosiheptide (Standard)
CAS:Nosiheptide (Standard) is the standard substance of Nosiheptide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nosiheptide (Multhiomycin), a thiopeptide antibiotic synthesized by Streptomyces actuosus, serves as a potent feed additive to promote animal growth. It functions by hindering bacterial protein synthesis and is distinguished by an indole side ring system and regiospecific hydroxyl groups on its macrocyclic core.Formula:C51H43N13O12S6Molecular weight:1222.36Nosiheptide
CAS:<p>A thiopeptide antibiotic produced by the bacterium Streptomyces actuosus. In addition, nosiheptide inhibits bacterial protein biosynthesis by acting during the elongation of the protein.</p>Formula:C51H43N13O12S6Purity:Min. 95%Color and Shape:PowderMolecular weight:1,222.36 g/molNosiheptide (>85%)
CAS:<p>Applications Nosiheptide is an antibacterial item used in feedstock and feed additives for chickens.<br>References Wang, H. et al.: J. Sci. Food. Agri., 93, 284 (2013); Kobayashi, I. et al.: Res. Dev. Rev., 2, 53 (1988);<br></p>Formula:C51H43N13O12S6Color and Shape:NeatMolecular weight:1222.36
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